STRINGSTRING
abcd2 abcd2 ldhb-2 ldhb-2 abcd2-2 abcd2-2 Timm17a.S Timm17a.S slc25a5 slc25a5 arf1 arf1 rab10 rab10 mfn2-2 mfn2-2 abcd3 abcd3 nme3 nme3 atad1-2 atad1-2 pex19-2 pex19-2 ehd1 ehd1 acox1 acox1 pex19 pex19 ins-2 ins-2 Asah1.L Asah1.L acox3 acox3 Acsl1.S Acsl1.S Tmem135 Tmem135 trim37-2 trim37-2 trim37 trim37 Vapb.L Vapb.L sumo2 sumo2 Agps.S Agps.S Agps.L Agps.L Uba1.S Uba1.S chmp1b chmp1b A0A1L8F4W5 A0A1L8F4W5 Pex11b.S Pex11b.S Pex11b.L Pex11b.L pex5 pex5 atad1 atad1 Pax-2 Pax-2 mfn2 mfn2 pex10 pex10 gstk1 gstk1 pax2 pax2 pex10-2 pex10-2 vps13d vps13d A0A1L8FND1 A0A1L8FND1 Arf5.L Arf5.L Acaa1.L Acaa1.L Acbd5.L Acbd5.L eci2 eci2 sirt5 sirt5 Vapa.L Vapa.L gdap1 gdap1 Pax1.S Pax1.S SPAST SPAST Gnpat.S Gnpat.S ELOVL4 ELOVL4 mff mff hadhb hadhb pex13 pex13 spast spast mff-2 mff-2 ins ins Pex16.S Pex16.S kifc3 kifc3 far1 far1 lonp2 lonp2 kifc3-2 kifc3-2 ldhb ldhb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
abcd2Uncharacterized protein. (731 aa)
ldhb-2L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
abcd2-2Uncharacterized protein. (731 aa)
Timm17a.SUncharacterized protein. (200 aa)
slc25a5Adenine nucleotide translocase; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
arf1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
rab10MGC68629 protein. (200 aa)
mfn2-2MGC81251 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (756 aa)
abcd370 kDa peroxisomal membrane protein. (657 aa)
nme3MGC85572 protein; Belongs to the NDK family. (169 aa)
atad1-2LOC495930 protein; Belongs to the AAA ATPase family. (360 aa)
pex19-2LOC496096 protein. (283 aa)
ehd1LOC495040 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (534 aa)
acox1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
pex19LOC733180 protein. (286 aa)
ins-2Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
Asah1.LUncharacterized protein. (479 aa)
acox3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (706 aa)
Acsl1.SUncharacterized protein. (728 aa)
Tmem135Uncharacterized protein. (198 aa)
trim37-2Uncharacterized protein. (1014 aa)
trim37Uncharacterized protein. (1014 aa)
Vapb.LMSP domain-containing protein. (289 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
Agps.SAlkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (646 aa)
Agps.LAlkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (606 aa)
Uba1.SUBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1044 aa)
chmp1bUncharacterized protein. (199 aa)
A0A1L8F4W5PlsC domain-containing protein; Belongs to the GPAT/DAPAT family. (660 aa)
Pex11b.SUncharacterized protein. (246 aa)
Pex11b.LUncharacterized protein. (245 aa)
pex5TPR_REGION domain-containing protein. (619 aa)
atad1AAA domain-containing protein; Belongs to the AAA ATPase family. (360 aa)
Pax-2Paired domain-containing protein. (495 aa)
mfn2Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (756 aa)
pex10RING-type domain-containing protein. (326 aa)
gstk1Glutathione S-transferase kappa. (223 aa)
pax2Paired domain-containing protein. (497 aa)
pex10-2RING-type domain-containing protein. (326 aa)
vps13dUncharacterized protein. (4359 aa)
A0A1L8FND1IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
Arf5.LUncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (232 aa)
Acaa1.LUncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (419 aa)
Acbd5.LAcyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters. (464 aa)
eci2ACB domain-containing protein. (397 aa)
sirt5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (309 aa)
Vapa.LMSP domain-containing protein. (236 aa)
gdap1Uncharacterized protein; Belongs to the GST superfamily. (347 aa)
Pax1.SPaired domain-containing protein. (449 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (600 aa)
Gnpat.SDihydroxyacetone phosphate acyltransferase. (664 aa)
ELOVL4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (335 aa)
mffMiff domain-containing protein. (304 aa)
hadhbUncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (470 aa)
pex13SH3 domain-containing protein. (398 aa)
spastSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (595 aa)
mff-2Miff domain-containing protein. (304 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
Pex16.SPeroxisomal membrane protein PEX16. (340 aa)
kifc3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (850 aa)
far1Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
lonp2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (856 aa)
kifc3-2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (856 aa)
ldhbL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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