6 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Dna2.S	Uncharacterized protein. (1053 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	rad50	Zinc-hook domain-containing protein. (1311 aa)
	rad50-2	Zinc-hook domain-containing protein. (1312 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dna2.S	Hus1	A0A1L8FF41	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.950
Dna2.S	rad50	A0A1L8FF41	A0A1L8GVF0	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.812
Dna2.S	rad50-2	A0A1L8FF41	A0A1L8GXM0	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.812
Dna2.S	rad9a	A0A1L8FF41	Q7ZZU5	Uncharacterized protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.969
Dna2.S	topbp1	A0A1L8FF41	A0A1L8FWJ6	Uncharacterized protein.	Uncharacterized protein.	0.971
Hus1	Dna2.S	Q8JHD8	A0A1L8FF41	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.950
Hus1	rad50	Q8JHD8	A0A1L8GVF0	Checkpoint protein; Belongs to the HUS1 family.	Zinc-hook domain-containing protein.	0.677
Hus1	rad50-2	Q8JHD8	A0A1L8GXM0	Checkpoint protein; Belongs to the HUS1 family.	Zinc-hook domain-containing protein.	0.674
Hus1	rad9a	Q8JHD8	Q7ZZU5	Checkpoint protein; Belongs to the HUS1 family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.999
Hus1	topbp1	Q8JHD8	A0A1L8FWJ6	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.998
rad50	Dna2.S	A0A1L8GVF0	A0A1L8FF41	Zinc-hook domain-containing protein.	Uncharacterized protein.	0.812
rad50	Hus1	A0A1L8GVF0	Q8JHD8	Zinc-hook domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.677
rad50	rad50-2	A0A1L8GVF0	A0A1L8GXM0	Zinc-hook domain-containing protein.	Zinc-hook domain-containing protein.	0.900
rad50	rad9a	A0A1L8GVF0	Q7ZZU5	Zinc-hook domain-containing protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.645
rad50	topbp1	A0A1L8GVF0	A0A1L8FWJ6	Zinc-hook domain-containing protein.	Uncharacterized protein.	0.810
rad50-2	Dna2.S	A0A1L8GXM0	A0A1L8FF41	Zinc-hook domain-containing protein.	Uncharacterized protein.	0.812
rad50-2	Hus1	A0A1L8GXM0	Q8JHD8	Zinc-hook domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.674
rad50-2	rad50	A0A1L8GXM0	A0A1L8GVF0	Zinc-hook domain-containing protein.	Zinc-hook domain-containing protein.	0.900
rad50-2	rad9a	A0A1L8GXM0	Q7ZZU5	Zinc-hook domain-containing protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.644
rad50-2	topbp1	A0A1L8GXM0	A0A1L8FWJ6	Zinc-hook domain-containing protein.	Uncharacterized protein.	0.810