28 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F2r.L	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (419 aa)
	Tjp2.L	Uncharacterized protein. (430 aa)
	tjp3	Uncharacterized protein; Belongs to the MAGUK family. (1025 aa)
	f2r	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (418 aa)
	Slc2a4.L	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	Tjp1.S	Uncharacterized protein; Belongs to the MAGUK family. (1705 aa)
	Pawr.L	Uncharacterized protein. (346 aa)
	pawr	Uncharacterized protein. (349 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Prkch.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (691 aa)
	cgn-2	Myosin_tail_1 domain-containing protein. (1368 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	Mark1.S	Non-specific serine/threonine protein kinase. (792 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	rbl2	Uncharacterized protein. (1087 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	nup62	Nuclear pore complex glycoprotein p62. (547 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	tjp3-2	MGC52795 protein; Belongs to the MAGUK family. (1010 aa)
	rab3b	MGC84786 protein. (217 aa)
	pard6b	Uncharacterized protein. (377 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	sympk	Uncharacterized protein. (1202 aa)
	ins-2	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	cgn	Myosin_tail_1 domain-containing protein. (1368 aa)
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FND1	Cdh3.S	A0A1L8FND1	A0A1L8GET9	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.590
A0A1L8FND1	Slc2a4.L	A0A1L8FND1	A0A1L8H4N2	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.924
A0A1L8FND1	actl6a	A0A1L8FND1	Q7ZYI5	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Baf53a-pending-prov protein; Belongs to the actin family.	0.733
A0A1L8FND1	cdh1	A0A1L8FND1	A0A1L8GKV4	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.590
A0A1L8FND1	cdh3	A0A1L8FND1	A0A1L8GKW6	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.588
A0A1L8FND1	ins	A0A1L8FND1	A0A1L8GD41	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.907
A0A1L8FND1	ins-2	A0A1L8FND1	B7ZQP1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.905
Cdh3.S	A0A1L8FND1	A0A1L8GET9	A0A1L8FND1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.590
Cdh3.S	Prkci.L	A0A1L8GET9	A0A1L8GAK2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.694
Cdh3.S	Tjp1.S	A0A1L8GET9	A0A1L8H090	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Belongs to the MAGUK family.	0.949
Cdh3.S	Tjp2.L	A0A1L8GET9	A0A1L8HYU8	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.642
Cdh3.S	actl6a	A0A1L8GET9	Q7ZYI5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Baf53a-pending-prov protein; Belongs to the actin family.	0.931
Cdh3.S	cdh1	A0A1L8GET9	A0A1L8GKV4	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.903
Cdh3.S	cdh3	A0A1L8GET9	A0A1L8GKW6	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
Cdh3.S	cgn	A0A1L8GET9	A0A1L8F572	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Myosin_tail_1 domain-containing protein.	0.485
Cdh3.S	cgn-2	A0A1L8GET9	A0A1L8FDB5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Myosin_tail_1 domain-containing protein.	0.485
Cdh3.S	ins	A0A1L8GET9	A0A1L8GD41	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.600
Cdh3.S	ins-2	A0A1L8GET9	B7ZQP1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.600
Cdh3.S	pard6b	A0A1L8GET9	A0A1L8ELH2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.573
Cdh3.S	pard6b-2	A0A1L8GET9	A0A1L8ESP6	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.573