STRINGSTRING
grb2 grb2 mapk1 mapk1 Bcr.L Bcr.L Mapk1.L Mapk1.L src src ptpn11b ptpn11b Ptpn11.S Ptpn11.S c-Jun c-Jun bcr bcr Cd247.L Cd247.L Jun.L Jun.L rag1-2 rag1-2 rag1 rag1 cd3e-2 cd3e-2 thy1 thy1 cd3e cd3e Shc1.L Shc1.L shc1 shc1 grb2-2 grb2-2 cd40 cd40
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
grb2Uncharacterized protein. (229 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
Bcr.LUncharacterized protein. (1180 aa)
Mapk1.LMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
srcTyrosine-protein kinase. (532 aa)
ptpn11bTyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
Ptpn11.STyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
c-JunC-Jun protein; Belongs to the bZIP family. (312 aa)
bcrUncharacterized protein. (1160 aa)
Cd247.LUncharacterized protein. (217 aa)
Jun.LBZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
rag1-2V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1045 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1045 aa)
cd3e-2Uncharacterized protein. (179 aa)
thy1Ig-like domain-containing protein. (165 aa)
cd3eIGc2 domain-containing protein. (182 aa)
Shc1.LUncharacterized protein. (601 aa)
shc1Uncharacterized protein. (605 aa)
grb2-2Uncharacterized protein. (229 aa)
cd40TNFR-Cys domain-containing protein. (280 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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