20 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ldlr.L	Uncharacterized protein. (910 aa)
	A0A1L8ENW1	Uncharacterized protein. (4101 aa)
	A0A1L8EVT7	Uncharacterized protein. (4493 aa)
	Lrp2.L	Uncharacterized protein. (4658 aa)
	nid2	Uncharacterized protein. (1531 aa)
	Nid2.L	Uncharacterized protein. (1530 aa)
	sorl1	Uncharacterized protein. (2199 aa)
	nid1	Uncharacterized protein. (1228 aa)
	nid1-2	Uncharacterized protein. (1228 aa)
	lrp4	Uncharacterized protein. (1906 aa)
	lrp8	Uncharacterized protein. (933 aa)
	lrp4-2	Uncharacterized protein. (1908 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	lrp8-2	Uncharacterized protein. (941 aa)
	A0A1L8GQT6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	Lrp1.S	Uncharacterized protein. (4544 aa)
	A0A1L8HI17	Uncharacterized protein. (4543 aa)
	Egf.L	Uncharacterized protein. (1031 aa)
	A0A1L8HXA8	Uncharacterized protein. (896 aa)
	vldlr	Uncharacterized protein. (894 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GQT6	Egf.L	A0A1L8GQT6	A0A1L8HUT3	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Uncharacterized protein.	0.432
A0A1L8GQT6	Lrp5.L	A0A1L8GQT6	A0A1L8GJX4	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Uncharacterized protein.	0.984
Egf.L	A0A1L8GQT6	A0A1L8HUT3	A0A1L8GQT6	Uncharacterized protein.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.432
Egf.L	Ldlr.L	A0A1L8HUT3	A0A310TPH7	Uncharacterized protein.	Uncharacterized protein.	0.410
Egf.L	Lrp2.L	A0A1L8HUT3	A0A1L8EWA8	Uncharacterized protein.	Uncharacterized protein.	0.595
Egf.L	Lrp5.L	A0A1L8HUT3	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.465
Egf.L	lrp4	A0A1L8HUT3	A0A1L8GDI9	Uncharacterized protein.	Uncharacterized protein.	0.600
Egf.L	lrp4-2	A0A1L8HUT3	A0A1L8GIP6	Uncharacterized protein.	Uncharacterized protein.	0.600
Ldlr.L	Egf.L	A0A310TPH7	A0A1L8HUT3	Uncharacterized protein.	Uncharacterized protein.	0.410
Lrp2.L	Egf.L	A0A1L8EWA8	A0A1L8HUT3	Uncharacterized protein.	Uncharacterized protein.	0.595
Lrp5.L	A0A1L8GQT6	A0A1L8GJX4	A0A1L8GQT6	Uncharacterized protein.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.984
Lrp5.L	Egf.L	A0A1L8GJX4	A0A1L8HUT3	Uncharacterized protein.	Uncharacterized protein.	0.465
lrp4	Egf.L	A0A1L8GDI9	A0A1L8HUT3	Uncharacterized protein.	Uncharacterized protein.	0.600
lrp4-2	Egf.L	A0A1L8GIP6	A0A1L8HUT3	Uncharacterized protein.	Uncharacterized protein.	0.600