(189 nodes) Calcium-binding EGF-like domain network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gas6-2	Gas6-prov protein. (669 aa)
	dner-2	Dnera protein. (678 aa)
	X-Delta-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa)
	Bmp1	Metalloendopeptidase. (977 aa)
	3a	Mannose-binding lectin-associated serine protease-3a; Belongs to the peptidase S1 family. (717 aa)
	MASP3b	Mannose-binding lectin-associated serine protease-3b; Belongs to the peptidase S1 family. (717 aa)
	LOC403365	DEL-1. (481 aa)
	A0A310UBS1	Uncharacterized protein. (1473 aa)
	A0A310UAN4	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (804 aa)
	A0A310U497	EGF-like domain-containing protein. (166 aa)
	A0A310U448	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (791 aa)
	Ldlr.L	Uncharacterized protein. (910 aa)
	A0A1L8I2L1	EGF-like domain-containing protein. (323 aa)
	A0A1L8I239	Uncharacterized protein. (4042 aa)
	A0A1L8I1D3	Uncharacterized protein. (2898 aa)
	vldlr	Uncharacterized protein. (894 aa)
	svep1	Uncharacterized protein. (3694 aa)
	A0A1L8HXJ8	Uncharacterized protein. (1611 aa)
	A0A1L8HXJ3	Uncharacterized protein. (963 aa)
	A0A1L8HX78	Uncharacterized protein. (710 aa)
	fbn3	Uncharacterized protein. (2864 aa)
	A0A1L8HUX9	Uncharacterized protein. (711 aa)
	Egf.L	Uncharacterized protein. (1031 aa)
	A0A1L8HTQ2	Uncharacterized protein. (1521 aa)
	A0A1L8HRU1	EGF-like domain-containing protein. (394 aa)
	Thbs4.S	Uncharacterized protein. (955 aa)
	A0A1L8HRB5	Uncharacterized protein. (3459 aa)
	A0A1L8HR91	Uncharacterized protein. (483 aa)
	A0A1L8HQY3	Uncharacterized protein. (2765 aa)
	A0A1L8HMV5	Uncharacterized protein. (2852 aa)
	A0A1L8HM48	Uncharacterized protein. (668 aa)
	A0A1L8HLW2	Uncharacterized protein. (5037 aa)
	Tll1.S	Metalloendopeptidase. (1007 aa)
	A0A1L8HLB9	Uncharacterized protein. (4670 aa)
	Slit2.S	Uncharacterized protein. (1530 aa)
	A0A1L8HI17	Uncharacterized protein. (4543 aa)
	gas6	Uncharacterized protein. (668 aa)
	A0A1L8HGJ6	Uncharacterized protein. (574 aa)
	celsr2	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (2911 aa)
	pros1-2	Uncharacterized protein. (669 aa)
	A0A1L8HCH5	Uncharacterized protein. (600 aa)
	A0A1L8HC95	Uncharacterized protein. (623 aa)
	A0A1L8HC93	Uncharacterized protein. (923 aa)
	A0A1L8HC63	Uncharacterized protein. (1788 aa)
	Fat3.S	Uncharacterized protein. (3417 aa)
	Lrp1.S	Uncharacterized protein. (4544 aa)
	A0A1L8H8W2	Uncharacterized protein. (452 aa)
	Egfl6.S	Uncharacterized protein. (542 aa)
	A0A1L8H5E4	Uncharacterized protein. (303 aa)
	pros1	Uncharacterized protein. (673 aa)
	A0A1L8H2W5	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (762 aa)
	A0A1L8H2P0	EGF-like domain-containing protein. (85 aa)
	A0A1L8H2M7	Uncharacterized protein. (732 aa)
	A0A1L8H2M4	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1254 aa)
	A0A1L8H2M3	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (719 aa)
	A0A1L8H2M0	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1377 aa)
	A0A1L8H2E9	Uncharacterized protein. (2404 aa)
	bmp1	Metalloendopeptidase. (976 aa)
	A0A1L8H0J8	Uncharacterized protein. (2883 aa)
	creld2	Uncharacterized protein. (361 aa)
	Nell2.L	Uncharacterized protein. (814 aa)
	A0A1L8GXF4	Uncharacterized protein. (1273 aa)
	A0A1L8GW56	Uncharacterized protein. (978 aa)
	Fbln1.L	Uncharacterized protein. (534 aa)
	A0A1L8GVD2	Uncharacterized protein. (1266 aa)
	nell2	Uncharacterized protein. (814 aa)
	A0A1L8GTZ5	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (2981 aa)
	Creld2.S	Uncharacterized protein. (361 aa)
	A0A1L8GSW8	Uncharacterized protein. (2869 aa)
	A0A1L8GSI8	Uncharacterized protein. (1675 aa)
	A0A1L8GRM4	Uncharacterized protein. (2165 aa)
	A0A1L8GQK0	Uncharacterized protein. (1478 aa)
	A0A1L8GPD6	Uncharacterized protein. (1104 aa)
	Hmcn1.L	Uncharacterized protein. (5466 aa)
	A0A1L8GNN6	Uncharacterized protein. (2572 aa)
	A0A1L8GN74	Uncharacterized protein. (1390 aa)
	lrp8-2	Uncharacterized protein. (941 aa)
	Adgrl4.L	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (733 aa)
	A0A1L8GLE8	Sushi domain-containing protein. (379 aa)
	ltbp3-2	Uncharacterized protein. (1146 aa)
	cd248-2	Uncharacterized protein. (777 aa)
	efemp2	Uncharacterized protein. (442 aa)
	A0A1L8GJ80	Uncharacterized protein. (1316 aa)
	lrp4-2	Uncharacterized protein. (1908 aa)
	A0A1L8GIG1	EGF-like domain-containing protein. (506 aa)
	heg1	Uncharacterized protein. (1184 aa)
	A0A1L8ENW1	Uncharacterized protein. (4101 aa)
	A0A1L8EQK3	Uncharacterized protein. (583 aa)
	heg1-2	Uncharacterized protein. (1186 aa)
	A0A1L8EVT7	Uncharacterized protein. (4493 aa)
	Lrp2.L	Uncharacterized protein. (4658 aa)
	A0A1L8EXQ3	Uncharacterized protein. (2763 aa)
	A0A1L8EY21	Uncharacterized protein. (940 aa)
	A0A1L8EY31	Uncharacterized protein. (853 aa)
	A0A1L8EY39	Uncharacterized protein. (562 aa)
	A0A1L8EY45	Uncharacterized protein. (703 aa)
	A0A1L8EY46	Uncharacterized protein. (865 aa)
	A0A1L8EY51	Uncharacterized protein. (832 aa)
	A0A1L8EY58	Uncharacterized protein. (923 aa)
	A0A1L8EY65	Uncharacterized protein. (889 aa)
	mgc89178	Uncharacterized protein. (558 aa)
	A0A1L8EY79	Uncharacterized protein. (947 aa)
	A0A1L8EY97	Uncharacterized protein. (651 aa)
	jag2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1223 aa)
	nid2	Uncharacterized protein. (1531 aa)
	Dlk1.S	Uncharacterized protein. (372 aa)
	Fbln5.S	Uncharacterized protein. (409 aa)
	A0A1L8F0V0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (650 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	crb2	Uncharacterized protein. (1472 aa)
	F9.S	Uncharacterized protein. (461 aa)
	A0A1L8F3L0	Uncharacterized protein. (2377 aa)
	A0A1L8F3M2	Uncharacterized protein. (280 aa)
	thbs3	Uncharacterized protein. (956 aa)
	notch1	Uncharacterized protein. (2521 aa)
	Crb2.L	Uncharacterized protein. (1120 aa)
	f9	Uncharacterized protein. (463 aa)
	egfl8	Uncharacterized protein. (297 aa)
	A0A1L8F8S4	Uncharacterized protein. (840 aa)
	A0A1L8F8T3	Uncharacterized protein. (383 aa)
	A0A1L8F9J0	Uncharacterized protein. (433 aa)
	Dlk1.L	Uncharacterized protein. (382 aa)
	Nid2.L	Uncharacterized protein. (1530 aa)
	jag2-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1227 aa)
	dll4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (675 aa)
	Thbs3.L	Uncharacterized protein. (964 aa)
	Slit1.S	Uncharacterized protein. (1529 aa)
	A0A1L8FEZ0	Uncharacterized protein. (697 aa)
	oit3	Uncharacterized protein. (551 aa)
	masp2	Uncharacterized protein; Belongs to the peptidase S1 family. (689 aa)
	megf6	Uncharacterized protein. (1617 aa)
	megf8	Uncharacterized protein. (2730 aa)
	A0A1L8FIF2	Uncharacterized protein; Belongs to the peptidase S1 family. (708 aa)
	C1s.L	Uncharacterized protein; Belongs to the peptidase S1 family. (687 aa)
	A0A1L8FJF5	Uncharacterized protein. (1320 aa)
	Tll2.L	Metalloendopeptidase. (1019 aa)
	Oit3.L	Uncharacterized protein. (550 aa)
	masp2-2	CUB domain-containing protein. (183 aa)
	megf6-2	Uncharacterized protein. (1613 aa)
	megf8-2	Uncharacterized protein. (2730 aa)
	Matn2.S	Uncharacterized protein. (840 aa)
	A0A1L8FVN0	Uncharacterized protein. (3628 aa)
	vwde	Uncharacterized protein. (1789 aa)
	Matn2.L	Uncharacterized protein. (886 aa)
	A0A1L8G0G4	Uncharacterized protein. (1011 aa)
	jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1206 aa)
	dlk2	Uncharacterized protein. (418 aa)
	thbd	Uncharacterized protein. (543 aa)
	Cd93.S	Uncharacterized protein. (599 aa)
	efemp1	Uncharacterized protein. (460 aa)
	Fbln7.S	Uncharacterized protein. (426 aa)
	Ltbp1.S	Uncharacterized protein. (1690 aa)
	dll1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
	nid1	Uncharacterized protein. (1228 aa)
	A0A1L8G3Z6	Uncharacterized protein. (8403 aa)
	dner	Uncharacterized protein. (678 aa)
	Tpo.S	Uncharacterized protein. (764 aa)
	cd93	Uncharacterized protein. (590 aa)
	thbd-2	Uncharacterized protein. (540 aa)
	A0A1L8G695	Uncharacterized protein. (1085 aa)
	dlk2-2	Uncharacterized protein. (413 aa)
	fbln7	Uncharacterized protein. (439 aa)
	Jag1.L	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
	A0A1L8G729	Uncharacterized protein. (1442 aa)
	efemp1-2	Uncharacterized protein. (458 aa)
	nid1-2	Uncharacterized protein. (1228 aa)
	ltbp1	Uncharacterized protein. (1691 aa)
	A0A1L8G9Q2	Uncharacterized protein. (1914 aa)
	A0A1L8G9T8	Uncharacterized protein. (2545 aa)
	A0A1L8G9W4	Uncharacterized protein. (1044 aa)
	A0A1L8GA52	Uncharacterized protein. (729 aa)
	A0A1L8GA69	Uncharacterized protein. (1919 aa)
	A0A1L8GA85	Uncharacterized protein. (1171 aa)
	sned1	Uncharacterized protein. (1697 aa)
	cd248	Uncharacterized protein. (741 aa)
	ltbp3	Uncharacterized protein. (1146 aa)
	lrp4	Uncharacterized protein. (1906 aa)
	nell1	Uncharacterized protein. (808 aa)
	scube2	Uncharacterized protein. (1003 aa)
	adgrl4	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (733 aa)
	A0A1L8GFE3	Sushi domain-containing protein. (427 aa)
	lrp8	Uncharacterized protein. (933 aa)
	A0A1L8GGU0	Uncharacterized protein. (2447 aa)
	A0A1L8GHH6	Uncharacterized protein. (989 aa)
	A0A1L8GHU3	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (3232 aa)
	scube2-2	Uncharacterized protein. (946 aa)
	dll1-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
	egfl7	Egfl7 protein. (280 aa)
	f10	MGC68454 protein. (462 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
3a	C1s.L	B7ZRP7	A0A1L8FIG6	Mannose-binding lectin-associated serine protease-3a; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.619
3a	masp2	B7ZRP7	A0A1L8FF99	Mannose-binding lectin-associated serine protease-3a; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.847
3a	masp2-2	B7ZRP7	A0A1L8FKW9	Mannose-binding lectin-associated serine protease-3a; Belongs to the peptidase S1 family.	CUB domain-containing protein.	0.830
A0A1L8EY39	A0A1L8H5E4	A0A1L8EY39	A0A1L8H5E4	Uncharacterized protein.	Uncharacterized protein.	0.403
A0A1L8F0V0	A0A1L8F3L0	A0A1L8F0V0	A0A1L8F3L0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.927
A0A1L8F0V0	A0A1L8GGU0	A0A1L8F0V0	A0A1L8GGU0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.877
A0A1L8F0V0	A0A1L8GNN6	A0A1L8F0V0	A0A1L8GNN6	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.665
A0A1L8F0V0	A0A1L8GRM4	A0A1L8F0V0	A0A1L8GRM4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.901
A0A1L8F0V0	A0A1L8H2E9	A0A1L8F0V0	A0A1L8H2E9	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.901
A0A1L8F0V0	Notch1.S	A0A1L8F0V0	A0A1L8F124	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.927
A0A1L8F0V0	dll4	A0A1L8F0V0	A0A1L8FB19	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.411
A0A1L8F0V0	notch1	A0A1L8F0V0	A0A1L8F627	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.927
A0A1L8F3L0	A0A1L8F0V0	A0A1L8F3L0	A0A1L8F0V0	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.927
A0A1L8F3L0	A0A1L8GRM4	A0A1L8F3L0	A0A1L8GRM4	Uncharacterized protein.	Uncharacterized protein.	0.410
A0A1L8F3L0	A0A1L8H2E9	A0A1L8F3L0	A0A1L8H2E9	Uncharacterized protein.	Uncharacterized protein.	0.410
A0A1L8F3L0	Dlk1.L	A0A1L8F3L0	A0A1L8F9X2	Uncharacterized protein.	Uncharacterized protein.	0.485
A0A1L8F3L0	Dlk1.S	A0A1L8F3L0	A0A1L8F063	Uncharacterized protein.	Uncharacterized protein.	0.485
A0A1L8F3L0	Jag1.L	A0A1L8F3L0	A0A1L8G723	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.988
A0A1L8F3L0	Tpo.S	A0A1L8F3L0	A0A1L8G5D6	Uncharacterized protein.	Uncharacterized protein.	0.466
A0A1L8F3L0	X-Delta-2	A0A1L8F3L0	P79941	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.927