33 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (579 aa)
	A0A1L8G9J6	BRCT domain-containing protein. (154 aa)
	Ect2.S	Uncharacterized protein. (987 aa)
	A0A1L8G3L5	BRCT domain-containing protein. (453 aa)
	Fcp1	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (979 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Paxip1.L	Uncharacterized protein. (1320 aa)
	Ctdp1.S	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (977 aa)
	ect2	Uncharacterized protein. (986 aa)
	A0A1L8GS64	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (604 aa)
	A0A1L8GSW6	Uncharacterized protein. (2175 aa)
	tp53bp1	Uncharacterized protein. (2179 aa)
	lig4	DNA ligase. (911 aa)
	rev1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1230 aa)
	A0A1L8HAQ9	Poly [ADP-ribose] polymerase. (1260 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
	Xrcc1.S	Uncharacterized protein. (591 aa)
	slf1	ANK_REP_REGION domain-containing protein. (904 aa)
	PES1-2	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (638 aa)
	rev1-2	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1237 aa)
	A0A1L8HJ48	Poly [ADP-ribose] polymerase. (1455 aa)
	A0A1L8EPM6	ANK_REP_REGION domain-containing protein. (400 aa)
	Lig3.L	DNA ligase. (988 aa)
	Brca1.L	Uncharacterized protein. (1582 aa)
	bard1	Uncharacterized protein. (839 aa)
	mdc1	Uncharacterized protein. (2103 aa)
	dntt	DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (507 aa)
	poll	BRCT domain-containing protein; Belongs to the DNA polymerase type-X family. (577 aa)
	Xrcc1.L	Uncharacterized protein. (651 aa)
	paxip1	Uncharacterized protein. (1334 aa)
	parp4.1	Poly [ADP-ribose] polymerase. (1459 aa)
	A0A1L8HJA6	Poly [ADP-ribose] polymerase. (1471 aa)
	rfc1	Replication factor C subunit 1. (1147 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EPM6	A0A1L8GSW6	A0A1L8EPM6	A0A1L8GSW6	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.823
A0A1L8EPM6	Brca1.L	A0A1L8EPM6	A0A1L8ETS4	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.994
A0A1L8EPM6	PES1	A0A1L8EPM6	A0A1L8HPX4	ANK_REP_REGION domain-containing protein.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.423
A0A1L8EPM6	PES1-2	A0A1L8EPM6	A0A1L8HZU0	ANK_REP_REGION domain-containing protein.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.423
A0A1L8EPM6	Paxip1.L	A0A1L8EPM6	A0A1L8FV59	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.782
A0A1L8EPM6	bard1	A0A1L8EPM6	A0A1L8EWU9	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.505
A0A1L8EPM6	lig4	A0A1L8EPM6	Q6GLS1	ANK_REP_REGION domain-containing protein.	DNA ligase.	0.446
A0A1L8EPM6	mdc1	A0A1L8EPM6	A0A1L8F8K7	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.782
A0A1L8EPM6	parp1	A0A1L8EPM6	Q2NLA7	ANK_REP_REGION domain-containing protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.438
A0A1L8EPM6	paxip1	A0A1L8EPM6	A0A1L8FQI7	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.782
A0A1L8EPM6	rev1	A0A1L8EPM6	A0A1L8H8Q0	ANK_REP_REGION domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.404
A0A1L8EPM6	rev1-2	A0A1L8EPM6	A0A1L8HGZ7	ANK_REP_REGION domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.404
A0A1L8EPM6	rfc1	A0A1L8EPM6	A0A1L8HTJ6	ANK_REP_REGION domain-containing protein.	Replication factor C subunit 1.	0.598
A0A1L8EPM6	slf1	A0A1L8EPM6	A0A1L8I1R9	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.984
A0A1L8EPM6	topbp1	A0A1L8EPM6	A0A1L8FWJ6	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.981
A0A1L8EPM6	tp53bp1	A0A1L8EPM6	A0A1L8H0P7	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.823
A0A1L8G3L5	A0A1L8GSW6	A0A1L8G3L5	A0A1L8GSW6	BRCT domain-containing protein.	Uncharacterized protein.	0.659
A0A1L8G3L5	Paxip1.L	A0A1L8G3L5	A0A1L8FV59	BRCT domain-containing protein.	Uncharacterized protein.	0.564
A0A1L8G3L5	mdc1	A0A1L8G3L5	A0A1L8F8K7	BRCT domain-containing protein.	Uncharacterized protein.	0.564
A0A1L8G3L5	paxip1	A0A1L8G3L5	A0A1L8FQI7	BRCT domain-containing protein.	Uncharacterized protein.	0.564