(14 nodes) Phosphotyrosine-binding domain (IRS1-like) network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8H929	Uncharacterized protein. (1008 aa)
	Irs4.S	Uncharacterized protein. (1088 aa)
	irs4	Uncharacterized protein. (1077 aa)
	A0A1L8G4J8	Uncharacterized protein. (1123 aa)
	Irs1.S	Uncharacterized protein. (1227 aa)
	Dok2.S	Uncharacterized protein. (428 aa)
	Frs2.S	IRS-type PTB domain-containing protein. (509 aa)
	frs2	IRS-type PTB domain-containing protein. (518 aa)
	dok2	Uncharacterized protein. (414 aa)
	A0A1L8H482	Uncharacterized protein. (814 aa)
	Bfar.L	Uncharacterized protein. (598 aa)
	A0A1L8HH28	Uncharacterized protein. (1011 aa)
	A0A1L8HK23	IRS-type PTB domain-containing protein. (526 aa)
	frs3	Frs3 protein. (517 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8G4J8	A0A1L8H482	A0A1L8G4J8	A0A1L8H482	Uncharacterized protein.	Uncharacterized protein.	0.908
A0A1L8G4J8	Irs1.S	A0A1L8G4J8	A0A1L8GB03	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8H482	A0A1L8G4J8	A0A1L8H482	A0A1L8G4J8	Uncharacterized protein.	Uncharacterized protein.	0.908
A0A1L8H482	Irs1.S	A0A1L8H482	A0A1L8GB03	Uncharacterized protein.	Uncharacterized protein.	0.908
Frs2.S	Irs4.S	A0A1L8GUK0	A0A1L8F2Q2	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.424
Frs2.S	frs3	A0A1L8GUK0	Q6IR73	IRS-type PTB domain-containing protein.	Frs3 protein.	0.513
Frs2.S	irs4	A0A1L8GUK0	A0A1L8F7C7	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.424
Irs1.S	A0A1L8G4J8	A0A1L8GB03	A0A1L8G4J8	Uncharacterized protein.	Uncharacterized protein.	0.900
Irs1.S	A0A1L8H482	A0A1L8GB03	A0A1L8H482	Uncharacterized protein.	Uncharacterized protein.	0.908
Irs1.S	frs2	A0A1L8GB03	A0A1L8GYJ1	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.467
Irs4.S	Frs2.S	A0A1L8F2Q2	A0A1L8GUK0	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.424
Irs4.S	frs2	A0A1L8F2Q2	A0A1L8GYJ1	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.471
frs2	Irs1.S	A0A1L8GYJ1	A0A1L8GB03	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.467
frs2	Irs4.S	A0A1L8GYJ1	A0A1L8F2Q2	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.471
frs2	frs3	A0A1L8GYJ1	Q6IR73	IRS-type PTB domain-containing protein.	Frs3 protein.	0.541
frs2	irs4	A0A1L8GYJ1	A0A1L8F7C7	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.471
frs3	Frs2.S	Q6IR73	A0A1L8GUK0	Frs3 protein.	IRS-type PTB domain-containing protein.	0.513
frs3	frs2	Q6IR73	A0A1L8GYJ1	Frs3 protein.	IRS-type PTB domain-containing protein.	0.541
irs4	Frs2.S	A0A1L8F7C7	A0A1L8GUK0	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.424
irs4	frs2	A0A1L8F7C7	A0A1L8GYJ1	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.471