(13 nodes) Orange domain network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hes7.2	Uncharacterized protein. (245 aa)
	hes5.2	Enhancer of split related protein 3/7b. (159 aa)
	hes5.2-2	Enhancer of split related protein-7. (158 aa)
	hes4	Uncharacterized protein. (277 aa)
	hey1	Uncharacterized protein. (294 aa)
	hey1-2	Uncharacterized protein. (298 aa)
	hes1	Uncharacterized protein. (267 aa)
	hey2	Uncharacterized protein. (334 aa)
	hes1-2	Uncharacterized protein. (267 aa)
	A0A1L8GQD9	Uncharacterized protein. (421 aa)
	A0A1L8GVX4	Uncharacterized protein. (461 aa)
	Esr-5.L	Uncharacterized protein. (211 aa)
	Hes4.L	Orange domain-containing protein. (171 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Export your current network:

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file format is 'PNG': portable network graphic

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esr-5.L	Hes4.L	A0A1L8H3C3	A0A310TLD4	Uncharacterized protein.	Orange domain-containing protein.	0.477
Hes4.L	Esr-5.L	A0A310TLD4	A0A1L8H3C3	Orange domain-containing protein.	Uncharacterized protein.	0.477
hes1	hey1	A0A1L8G421	A0A1L8FTD9	Uncharacterized protein.	Uncharacterized protein.	0.491
hes1	hey1-2	A0A1L8G421	A0A1L8FZB3	Uncharacterized protein.	Uncharacterized protein.	0.496
hes1	hey2	A0A1L8G421	A0A1L8G8T5	Uncharacterized protein.	Uncharacterized protein.	0.465
hes1-2	hey1	A0A1L8G9X1	A0A1L8FTD9	Uncharacterized protein.	Uncharacterized protein.	0.494
hes1-2	hey1-2	A0A1L8G9X1	A0A1L8FZB3	Uncharacterized protein.	Uncharacterized protein.	0.500
hes1-2	hey2	A0A1L8G9X1	A0A1L8G8T5	Uncharacterized protein.	Uncharacterized protein.	0.469
hey1	hes1	A0A1L8FTD9	A0A1L8G421	Uncharacterized protein.	Uncharacterized protein.	0.491
hey1	hes1-2	A0A1L8FTD9	A0A1L8G9X1	Uncharacterized protein.	Uncharacterized protein.	0.494
hey1	hey1-2	A0A1L8FTD9	A0A1L8FZB3	Uncharacterized protein.	Uncharacterized protein.	0.900
hey1	hey2	A0A1L8FTD9	A0A1L8G8T5	Uncharacterized protein.	Uncharacterized protein.	0.905
hey1-2	hes1	A0A1L8FZB3	A0A1L8G421	Uncharacterized protein.	Uncharacterized protein.	0.496
hey1-2	hes1-2	A0A1L8FZB3	A0A1L8G9X1	Uncharacterized protein.	Uncharacterized protein.	0.500
hey1-2	hey1	A0A1L8FZB3	A0A1L8FTD9	Uncharacterized protein.	Uncharacterized protein.	0.900
hey1-2	hey2	A0A1L8FZB3	A0A1L8G8T5	Uncharacterized protein.	Uncharacterized protein.	0.906
hey2	hes1	A0A1L8G8T5	A0A1L8G421	Uncharacterized protein.	Uncharacterized protein.	0.465
hey2	hes1-2	A0A1L8G8T5	A0A1L8G9X1	Uncharacterized protein.	Uncharacterized protein.	0.469
hey2	hey1	A0A1L8G8T5	A0A1L8FTD9	Uncharacterized protein.	Uncharacterized protein.	0.905
hey2	hey1-2	A0A1L8G8T5	A0A1L8FZB3	Uncharacterized protein.	Uncharacterized protein.	0.906