(68 nodes) Amino sugar and nucleotide sugar metabolism network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Gmppa.S	NTP_transferase domain-containing protein. (421 aa)
	Galk1.L	Uncharacterized protein. (388 aa)
	gmppa	NTP_transferase domain-containing protein. (426 aa)
	amdhd2	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (408 aa)
	uap1l1	Uncharacterized protein. (508 aa)
	A0A1L8FER1	Uncharacterized protein. (915 aa)
	A0A1L8FJQ1	Uncharacterized protein. (919 aa)
	A0A1L8FLB0	Uncharacterized protein. (620 aa)
	Cmahp.L	Rieske domain-containing protein. (591 aa)
	A0A1L8G0R6	UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
	A0A1L8G2D2	Uncharacterized protein. (1243 aa)
	cyb5r4	Uncharacterized protein. (522 aa)
	ugp2	UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
	Pgm3.L	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. (542 aa)
	Cyb5r2.S	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (296 aa)
	Pgm1.L	Uncharacterized protein; Belongs to the phosphohexose mutase family. (562 aa)
	npl	Uncharacterized protein; Belongs to the DapA family. (305 aa)
	uap1	Uncharacterized protein. (527 aa)
	Pmm2.S	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (260 aa)
	gmppb	NTP_transferase domain-containing protein. (366 aa)
	fpgt	Fucokinase domain-containing protein. (574 aa)
	Cyb5r2.L	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (322 aa)
	gpi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	Fuk.L	Uncharacterized protein. (1086 aa)
	A0A1L8GLW9	Uncharacterized protein. (638 aa)
	A0A1L8GNA7	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (369 aa)
	gmppb-2	NTP_transferase domain-containing protein. (379 aa)
	cyb5r3	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (301 aa)
	A0A1L8GRU3	Phosphotransferase. (465 aa)
	Gfpt1.S	Uncharacterized protein. (711 aa)
	hkdc1	Uncharacterized protein. (916 aa)
	mpi	Mannose-6-phosphate isomerase. (424 aa)
	A0A1L8GUZ3	Uncharacterized protein. (915 aa)
	gnpda1	Glucosamine-6-phosphate isomerase. (289 aa)
	cmas	Uncharacterized protein. (402 aa)
	A0A1L8GX33	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (495 aa)
	A0A1L8GXC3	Uncharacterized protein. (657 aa)
	gnpda1-2	Glucosamine-6-phosphate isomerase. (288 aa)
	Hk2.L	Uncharacterized protein. (915 aa)
	A0A1L8GXW5	Phosphotransferase. (610 aa)
	mpi-2	Mannose-6-phosphate isomerase. (418 aa)
	hkdc1-2	Uncharacterized protein. (916 aa)
	Gck.L	Phosphotransferase. (495 aa)
	Chia.S	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (482 aa)
	A0A1L8H746	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (485 aa)
	uxs1	Uncharacterized protein. (421 aa)
	uxs1-2	Uncharacterized protein. (421 aa)
	A0A1L8HRD1	Beta-hexosaminidase. (517 aa)
	Nagk.L	BcrAD_BadFG domain-containing protein. (298 aa)
	ugdh	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
	pgm2l1	Uncharacterized protein. (610 aa)
	gnpda2	Glucosamine-6-phosphate isomerase. (275 aa)
	gne	Epimerase_2 domain-containing protein. (796 aa)
	hexb	Beta-hexosaminidase. (553 aa)
	Galt.S	Galactose-1-phosphate uridylyltransferase. (359 aa)
	Gale.S	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
	uap1-2	LOC100037187 protein. (523 aa)
	renbp	MGC114748 protein. (403 aa)
	pmm1	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (246 aa)
	nans	MGC84329 protein. (359 aa)
	chit1	MGC80644 protein; Belongs to the glycosyl hydrolase 18 family. (489 aa)
	gmds	MGC82624 protein. (369 aa)
	hk1	Hk1-A protein. (916 aa)
	nanp	MGC81095 protein. (240 aa)
	gnpnat1	Glucosamine 6-phosphate N-acetyltransferase. (184 aa)
	cyb5r3-2	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (301 aa)
	gfpt2	Gfpt1-prov protein. (681 aa)
	gale	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FER1	A0A1L8FJQ1	A0A1L8FER1	A0A1L8FJQ1	Uncharacterized protein.	Uncharacterized protein.	0.604
A0A1L8FER1	A0A1L8GLW9	A0A1L8FER1	A0A1L8GLW9	Uncharacterized protein.	Uncharacterized protein.	0.860
A0A1L8FER1	A0A1L8GNA7	A0A1L8FER1	A0A1L8GNA7	Uncharacterized protein.	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	0.760
A0A1L8FER1	A0A1L8GUZ3	A0A1L8FER1	A0A1L8GUZ3	Uncharacterized protein.	Uncharacterized protein.	0.607
A0A1L8FER1	A0A1L8GXC3	A0A1L8FER1	A0A1L8GXC3	Uncharacterized protein.	Uncharacterized protein.	0.726
A0A1L8FER1	A0A1L8GXW5	A0A1L8FER1	A0A1L8GXW5	Uncharacterized protein.	Phosphotransferase.	0.620
A0A1L8FER1	Fuk.L	A0A1L8FER1	A0A1L8GLE3	Uncharacterized protein.	Uncharacterized protein.	0.800
A0A1L8FER1	Gfpt1.S	A0A1L8FER1	A0A1L8GS48	Uncharacterized protein.	Uncharacterized protein.	0.801
A0A1L8FER1	Hk2.L	A0A1L8FER1	A0A1L8GXW0	Uncharacterized protein.	Uncharacterized protein.	0.607
A0A1L8FER1	Pgm1.L	A0A1L8FER1	A0A1L8GFG5	Uncharacterized protein.	Uncharacterized protein; Belongs to the phosphohexose mutase family.	0.859
A0A1L8FER1	Pgm3.L	A0A1L8FER1	A0A1L8G9U3	Uncharacterized protein.	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	0.513
A0A1L8FER1	Pmm2.S	A0A1L8FER1	A0A1L8GGM9	Uncharacterized protein.	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	0.760
A0A1L8FER1	amdhd2	A0A1L8FER1	A0A1L8EYA2	Uncharacterized protein.	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family.	0.926
A0A1L8FER1	gfpt2	A0A1L8FER1	Q7ZYF4	Uncharacterized protein.	Gfpt1-prov protein.	0.768
A0A1L8FER1	gnpda1	A0A1L8FER1	A0A1L8GVA6	Uncharacterized protein.	Glucosamine-6-phosphate isomerase.	0.842
A0A1L8FER1	gnpda1-2	A0A1L8FER1	A0A1L8GXG6	Uncharacterized protein.	Glucosamine-6-phosphate isomerase.	0.710
A0A1L8FER1	gnpda2	A0A1L8FER1	A0A1L8HTM5	Uncharacterized protein.	Glucosamine-6-phosphate isomerase.	0.710
A0A1L8FER1	gnpnat1	A0A1L8FER1	Q7T0Z6	Uncharacterized protein.	Glucosamine 6-phosphate N-acetyltransferase.	0.961
A0A1L8FER1	gpi	A0A1L8FER1	A0A1L8GL32	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.976
A0A1L8FER1	hk1	A0A1L8FER1	Q6GQB4	Uncharacterized protein.	Hk1-A protein.	0.602