(54 nodes) ABC transporters network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8EKD4	Uncharacterized protein. (1640 aa)
	A0A1L8EM17	Uncharacterized protein. (1610 aa)
	Abcc3.S	Uncharacterized protein. (1531 aa)
	abcb11	Uncharacterized protein. (1349 aa)
	A0A1L8EPJ7	Uncharacterized protein. (2016 aa)
	abca3	Uncharacterized protein. (1700 aa)
	A0A1L8ERP1	Uncharacterized protein. (1640 aa)
	A0A1L8ETB2	Uncharacterized protein. (1616 aa)
	abcc3	Uncharacterized protein. (1531 aa)
	abcb6	Uncharacterized protein. (849 aa)
	A0A1L8EW33	Uncharacterized protein. (1297 aa)
	A0A1L8EWN5	Uncharacterized protein. (2332 aa)
	abcc1	Uncharacterized protein. (1507 aa)
	abcc6	Uncharacterized protein. (1498 aa)
	abca3-2	Uncharacterized protein. (1700 aa)
	abcd1	Uncharacterized protein. (743 aa)
	abca2	Uncharacterized protein. (2537 aa)
	A0A1L8F7A7	Uncharacterized protein. (838 aa)
	Tap1.L	ABC transmembrane type-1 domain-containing protein. (493 aa)
	abcd4	Uncharacterized protein. (643 aa)
	abcc2	Uncharacterized protein. (1554 aa)
	A0A1L8FJP3	Uncharacterized protein. (1315 aa)
	A0A1L8FR94	Uncharacterized protein. (1265 aa)
	Abcb1.L	Uncharacterized protein. (1286 aa)
	A0A1L8FVY8	Uncharacterized protein. (1265 aa)
	A0A1L8FW23	Uncharacterized protein. (1261 aa)
	A0A1L8FW29	Uncharacterized protein. (1217 aa)
	Abcg5.S	ABC transporter domain-containing protein. (657 aa)
	A0A1L8G1H7	ABC transporter domain-containing protein. (604 aa)
	A0A1L8G3J8	Uncharacterized protein. (1406 aa)
	A0A1L8G6K1	Uncharacterized protein. (1282 aa)
	abcc10	Uncharacterized protein. (1500 aa)
	abcc5	Uncharacterized protein. (1437 aa)
	A0A1L8GI80	Uncharacterized protein. (1175 aa)
	Abca4.L	Uncharacterized protein. (1776 aa)
	abcd2	Uncharacterized protein. (731 aa)
	cftr	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
	A0A1L8GVV0	Uncharacterized protein. (924 aa)
	cftr-2	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
	abcd2-2	Uncharacterized protein. (731 aa)
	A0A1L8H5E7	ABC transporter domain-containing protein. (664 aa)
	A0A1L8H950	Uncharacterized protein. (1281 aa)
	abcg1	ABC transporter domain-containing protein. (663 aa)
	A0A1L8HCT7	Uncharacterized protein. (1289 aa)
	A0A1L8HGV6	Uncharacterized protein. (1428 aa)
	abcc4	Uncharacterized protein. (1324 aa)
	abcg2	ABC transporter domain-containing protein. (661 aa)
	abca1	Uncharacterized protein. (2265 aa)
	Abca1.L	Uncharacterized protein. (2171 aa)
	abcb9	Uncharacterized protein. (777 aa)
	A0A310U8H2	Uncharacterized protein. (742 aa)
	abcg2-2	LOC100036892 protein. (661 aa)
	abcd3	70 kDa peroxisomal membrane protein. (657 aa)
	tap2	Transporter associated with antigen processing 2. (714 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKD4	A0A1L8ERP1	A0A1L8EKD4	A0A1L8ERP1	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8EM17	A0A1L8ETB2	A0A1L8EM17	A0A1L8ETB2	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8EPJ7	A0A1L8EWN5	A0A1L8EPJ7	A0A1L8EWN5	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8EPJ7	abcd4	A0A1L8EPJ7	A0A1L8F990	Uncharacterized protein.	Uncharacterized protein.	0.461
A0A1L8ERP1	A0A1L8EKD4	A0A1L8ERP1	A0A1L8EKD4	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8ETB2	A0A1L8EM17	A0A1L8ETB2	A0A1L8EM17	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8EW33	abcb11	A0A1L8EW33	A0A1L8EP62	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8EWN5	A0A1L8EPJ7	A0A1L8EWN5	A0A1L8EPJ7	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8EWN5	abcd4	A0A1L8EWN5	A0A1L8F990	Uncharacterized protein.	Uncharacterized protein.	0.461
A0A1L8F7A7	Tap1.L	A0A1L8F7A7	A0A1L8F8D4	Uncharacterized protein.	ABC transmembrane type-1 domain-containing protein.	0.563
A0A1L8F7A7	abcb9	A0A1L8F7A7	A0A1L8I117	Uncharacterized protein.	Uncharacterized protein.	0.563
A0A1L8F7A7	tap2	A0A1L8F7A7	Q6XXY8	Uncharacterized protein.	Transporter associated with antigen processing 2.	0.596
A0A1L8FJP3	A0A1L8FW29	A0A1L8FJP3	A0A1L8FW29	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8FJP3	Abcb1.L	A0A1L8FJP3	A0A1L8FVP2	Uncharacterized protein.	Uncharacterized protein.	0.902
A0A1L8FW29	A0A1L8FJP3	A0A1L8FW29	A0A1L8FJP3	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8FW29	Abcb1.L	A0A1L8FW29	A0A1L8FVP2	Uncharacterized protein.	Uncharacterized protein.	0.902
A0A1L8G1H7	Abcg5.S	A0A1L8G1H7	A0A1L8G1F9	ABC transporter domain-containing protein.	ABC transporter domain-containing protein.	0.999
A0A1L8G1H7	abcc2	A0A1L8G1H7	A0A1L8FJH9	ABC transporter domain-containing protein.	Uncharacterized protein.	0.529
A0A1L8G3J8	A0A1L8HGV6	A0A1L8G3J8	A0A1L8HGV6	Uncharacterized protein.	Uncharacterized protein.	0.902
A0A1L8G3J8	abcc5	A0A1L8G3J8	A0A1L8GA45	Uncharacterized protein.	Uncharacterized protein.	0.900