30 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	srp68	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (600 aa)
	hspa5	Uncharacterized protein; Belongs to the heat shock protein 70 family. (658 aa)
	srp54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	srpra	SRP54 domain-containing protein. (651 aa)
	sec61g	Uncharacterized protein. (68 aa)
	srp9	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)
	srprb	Uncharacterized protein. (265 aa)
	Sec63.L	J domain-containing protein. (737 aa)
	immp1l	Mitochondrial inner membrane protease subunit. (165 aa)
	immp1l-2	Mitochondrial inner membrane protease subunit. (165 aa)
	sec61a1	Plug_translocon domain-containing protein. (476 aa)
	Spcs2.S	Uncharacterized protein. (194 aa)
	spcs3	Signal peptidase complex subunit 3. (180 aa)
	srp19	Uncharacterized protein. (142 aa)
	oxa1l	Uncharacterized protein. (428 aa)
	A0A1L8I2Z1	Signal peptidase complex catalytic subunit SEC11. (177 aa)
	Sec62.S	Uncharacterized protein. (404 aa)
	srp68-2	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (600 aa)
	srp14	MGC115450 protein. (110 aa)
	srp19-2	LOC495049 protein. (142 aa)
	MGC82823	Signal peptidase complex catalytic subunit SEC11. (179 aa)
	MGC82698	MGC82698 protein. (400 aa)
	srp9-2	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)
	sec63	MGC80164 protein. (755 aa)
	spcs3-2	Signal peptidase complex subunit 3. (180 aa)
	sec11a	Signal peptidase complex catalytic subunit SEC11. (179 aa)
	sec61a1-2	Sec61a1 protein. (476 aa)
	srp54-2	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	hspa5-2	Hspa5 protein; Belongs to the heat shock protein 70 family. (655 aa)
	sec61b	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8I2Z1	MGC82823	A0A1L8I2Z1	Q6AZG0	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex catalytic subunit SEC11.	0.900
A0A1L8I2Z1	Spcs2.S	A0A1L8I2Z1	A0A1L8HBA8	Signal peptidase complex catalytic subunit SEC11.	Uncharacterized protein.	0.908
A0A1L8I2Z1	sec11a	A0A1L8I2Z1	Q7SZ27	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex catalytic subunit SEC11.	0.900
A0A1L8I2Z1	spcs3	A0A1L8I2Z1	A0A1L8HLG3	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex subunit 3.	0.922
A0A1L8I2Z1	spcs3-2	A0A1L8I2Z1	Q6IP12	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex subunit 3.	0.922
A0A1L8I2Z1	srpra	A0A1L8I2Z1	A0A1L8FLC6	Signal peptidase complex catalytic subunit SEC11.	SRP54 domain-containing protein.	0.445
MGC82698	Sec62.S	Q6AZP2	A0A310U1L8	MGC82698 protein.	Uncharacterized protein.	0.902
MGC82698	Sec63.L	Q6AZP2	A0A1L8G8W1	MGC82698 protein.	J domain-containing protein.	0.996
MGC82698	Spcs2.S	Q6AZP2	A0A1L8HBA8	MGC82698 protein.	Uncharacterized protein.	0.572
MGC82698	hspa5	Q6AZP2	A0A1L8F6I3	MGC82698 protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.552
MGC82698	hspa5-2	Q6AZP2	Q8AVE3	MGC82698 protein.	Hspa5 protein; Belongs to the heat shock protein 70 family.	0.556
MGC82698	sec61a1	Q6AZP2	A0A1L8GPS0	MGC82698 protein.	Plug_translocon domain-containing protein.	0.947
MGC82698	sec61a1-2	Q6AZP2	Q7ZX87	MGC82698 protein.	Sec61a1 protein.	0.947
MGC82698	sec61b	Q6AZP2	Q8AVT7	MGC82698 protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.964
MGC82698	sec61g	Q6AZP2	A0A1L8FWK5	MGC82698 protein.	Uncharacterized protein.	0.979
MGC82698	sec63	Q6AZP2	Q6GQC5	MGC82698 protein.	MGC80164 protein.	0.996
MGC82698	srp19	Q6AZP2	A0A1L8HR28	MGC82698 protein.	Uncharacterized protein.	0.444
MGC82698	srp19-2	Q6AZP2	Q5XHA6	MGC82698 protein.	LOC495049 protein.	0.444
MGC82698	srp54	Q6AZP2	A0A1L8FAQ2	MGC82698 protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.429
MGC82698	srp54-2	Q6AZP2	Q7ZXH4	MGC82698 protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.429