STRINGSTRING
A0A1L8EKP1 A0A1L8EKP1 grb2 grb2 Map2k4.S Map2k4.S A0A1L8ENA1 A0A1L8ENA1 A0A1L8EPK3 A0A1L8EPK3 A0A1L8EQT4 A0A1L8EQT4 erbb2 erbb2 plcg1 plcg1 A0A1L8EYD3 A0A1L8EYD3 akt1 akt1 sos2 sos2 Elk1.S Elk1.S abl1 abl1 Pak3.L Pak3.L MGC78893 MGC78893 A0A1L8F415 A0A1L8F415 pak6 pak6 shc1 shc1 A0A1L8F5L4 A0A1L8F5L4 akt2 akt2 sos2-2 sos2-2 pak6-2 pak6-2 Shc1.L Shc1.L Camk2g.S Camk2g.S mapk10 mapk10 kras kras A0A1L8FHC4 A0A1L8FHC4 A0A1L8FJZ5 A0A1L8FJZ5 LOC733728.L LOC733728.L A0A1L8FK96 A0A1L8FK96 A0A1L8FKW5 A0A1L8FKW5 cbl cbl egfr egfr Myc.S Myc.S Ptk2.S Ptk2.S egfr-2 egfr-2 Ptk2.L Ptk2.L A0A1L8G061 A0A1L8G061 A0A1L8G1J0 A0A1L8G1J0 sos1 sos1 A0A1L8G3Z7 A0A1L8G3Z7 Pak2.S Pak2.S pik3cb pik3cb A0A1L8G610 A0A1L8G610 sos1-2 sos1-2 pik3cb-2 pik3cb-2 A0A1L8GBH3 A0A1L8GBH3 abl2 abl2 A0A1L8GJQ1 A0A1L8GJQ1 plcg2 plcg2 Jun.L Jun.L Abl2.L Abl2.L braf braf Cdkn1b.S Cdkn1b.S A0A1L8GRE9 A0A1L8GRE9 Tgfa.S Tgfa.S map2k1 map2k1 hbegf hbegf A0A1L8GWC5 A0A1L8GWC5 hbegf-2 hbegf-2 nrg4 nrg4 shc4 shc4 map2k1-2 map2k1-2 tgfa tgfa Map2k7.S Map2k7.S A0A1L8H5Q6 A0A1L8H5Q6 crk crk A0A1L8H6B5 A0A1L8H6B5 Rps6kb1.S Rps6kb1.S Cblb.S Cblb.S nck2 nck2 erbb3 erbb3 Crk.L Crk.L nras nras cdkn1a cdkn1a rps6kb1 rps6kb1 Cblb.L Cblb.L nck2-2 nck2-2 erbb3-2 erbb3-2 ereg ereg areg areg Btc.S Btc.S A0A1L8HNI8 A0A1L8HNI8 shc2 shc2 A0A1L8HPF0 A0A1L8HPF0 mapk1 mapk1 Egf.L Egf.L btc btc areg-2 areg-2 ereg-2 ereg-2 mapk10-2 mapk10-2 A0A1L8HW99 A0A1L8HW99 A0A1L8HWT4 A0A1L8HWT4 shc2-2 shc2-2 A0A1L8HZ53 A0A1L8HZ53 Mapk1.L Mapk1.L Gab1.L Gab1.L Cbl.S Cbl.S Plcg1.S Plcg1.S pak3 pak3 Stat5a Stat5a PIK3R1 PIK3R1 nck1 nck1 src src nck1-2 nck1-2 pak5 pak5 krasl krasl pik3r3 pik3r3 kras-2 kras-2 crkl crkl prkca prkca gab1 gab1 pik3r2 pik3r2 pik3r1 pik3r1 araf araf myc myc crkl-2 crkl-2 stat5b stat5b araf-2 araf-2 hras hras kras-3 kras-3 c-Jun c-Jun
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1L8EKP1Receptor protein-tyrosine kinase. (1290 aa)
grb2Uncharacterized protein. (229 aa)
Map2k4.SProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (439 aa)
A0A1L8ENA1Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)
A0A1L8EPK3Receptor protein-tyrosine kinase. (1256 aa)
A0A1L8EQT4Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
erbb2Receptor protein-tyrosine kinase. (1299 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1280 aa)
A0A1L8EYD3Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
sos2Uncharacterized protein. (1335 aa)
Elk1.SETS domain-containing protein. (469 aa)
abl1Tyrosine-protein kinase. (1122 aa)
Pak3.LNon-specific serine/threonine protein kinase. (564 aa)
MGC78893Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (485 aa)
A0A1L8F415Non-specific serine/threonine protein kinase. (660 aa)
pak6Non-specific serine/threonine protein kinase. (617 aa)
shc1Uncharacterized protein. (605 aa)
A0A1L8F5L4ETS domain-containing protein. (412 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa)
sos2-2Uncharacterized protein. (1332 aa)
pak6-2Non-specific serine/threonine protein kinase. (655 aa)
Shc1.LUncharacterized protein. (601 aa)
Camk2g.SProtein kinase domain-containing protein. (662 aa)
mapk10Mitogen-activated protein kinase. (426 aa)
krasUncharacterized protein. (186 aa)
A0A1L8FHC4Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
A0A1L8FJZ5Protein kinase domain-containing protein. (654 aa)
LOC733728.LEGF-like domain-containing protein. (142 aa)
A0A1L8FK96Uncharacterized protein. (358 aa)
A0A1L8FKW5Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2533 aa)
cblUncharacterized protein. (887 aa)
egfrReceptor protein-tyrosine kinase. (1208 aa)
Myc.SMyc_N domain-containing protein. (176 aa)
Ptk2.SUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1065 aa)
egfr-2Receptor protein-tyrosine kinase. (1210 aa)
Ptk2.LUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1097 aa)
A0A1L8G0611-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1305 aa)
A0A1L8G1J0Non-specific serine/threonine protein kinase. (717 aa)
sos1Uncharacterized protein. (1325 aa)
A0A1L8G3Z7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
Pak2.SNon-specific serine/threonine protein kinase. (517 aa)
pik3cbUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
A0A1L8G610Non-specific serine/threonine protein kinase. (717 aa)
sos1-2Uncharacterized protein. (1325 aa)
pik3cb-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
A0A1L8GBH3Non-specific serine/threonine protein kinase. (518 aa)
abl2Tyrosine-protein kinase. (1102 aa)
A0A1L8GJQ1Uncharacterized protein. (151 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1259 aa)
Jun.LBZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
Abl2.LTyrosine-protein kinase. (1102 aa)
brafUncharacterized protein. (802 aa)
Cdkn1b.SUncharacterized protein. (152 aa)
A0A1L8GRE9Protein kinase domain-containing protein. (455 aa)
Tgfa.SEGF-like domain-containing protein. (159 aa)
map2k1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
hbegfEGF-like domain-containing protein. (196 aa)
A0A1L8GWC5Uncharacterized protein. (149 aa)
hbegf-2EGF-like domain-containing protein. (196 aa)
nrg4EGF-like domain-containing protein. (99 aa)
shc4Uncharacterized protein. (568 aa)
map2k1-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
tgfaEGF-like domain-containing protein. (160 aa)
Map2k7.SProtein kinase domain-containing protein. (489 aa)
A0A1L8H5Q6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
crkUncharacterized protein. (297 aa)
A0A1L8H6B5Uncharacterized protein. (137 aa)
Rps6kb1.SRibosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
Cblb.SUncharacterized protein. (979 aa)
nck2Cytoplasmic protein. (381 aa)
erbb3Protein kinase domain-containing protein. (1331 aa)
Crk.LUncharacterized protein. (297 aa)
nrasUncharacterized protein. (189 aa)
cdkn1aUncharacterized protein. (261 aa)
rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (521 aa)
Cblb.LUncharacterized protein. (978 aa)
nck2-2Cytoplasmic protein. (381 aa)
erbb3-2Protein kinase domain-containing protein. (1347 aa)
eregUncharacterized protein. (156 aa)
aregEGF-like domain-containing protein. (226 aa)
Btc.SEGF-like domain-containing protein. (287 aa)
A0A1L8HNI8Uncharacterized protein. (721 aa)
shc2Uncharacterized protein. (624 aa)
A0A1L8HPF0Uncharacterized protein. (629 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
Egf.LUncharacterized protein. (1031 aa)
btcEGF-like domain-containing protein. (170 aa)
areg-2EGF-like domain-containing protein. (228 aa)
ereg-2Uncharacterized protein. (156 aa)
mapk10-2Mitogen-activated protein kinase. (444 aa)
A0A1L8HW99Uncharacterized protein. (576 aa)
A0A1L8HWT4Uncharacterized protein. (717 aa)
shc2-2Uncharacterized protein. (624 aa)
A0A1L8HZ53Uncharacterized protein. (628 aa)
Mapk1.LMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
Gab1.LPH domain-containing protein. (682 aa)
Cbl.SUncharacterized protein. (945 aa)
Plcg1.S1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1260 aa)
pak3Non-specific serine/threonine protein kinase. (549 aa)
Stat5aSignal transducer and activator of transcription. (781 aa)
PIK3R1Phosphoinositide-3-kinase. (722 aa)
nck1Cytoplasmic protein. (377 aa)
srcTyrosine-protein kinase. (532 aa)
nck1-2Cytoplasmic protein. (377 aa)
pak5Non-specific serine/threonine protein kinase. (650 aa)
kraslUncharacterized protein. (187 aa)
pik3r3MGC84470 protein. (461 aa)
kras-2Uncharacterized protein. (187 aa)
crklMGC84382 protein. (302 aa)
prkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
gab1MGC81548 protein. (691 aa)
pik3r2Pik3r2-prov protein. (457 aa)
pik3r1MGC80357 protein. (722 aa)
arafARAF protein. (595 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
crkl-2MGC81407 protein. (302 aa)
stat5bSignal transducer and activator of transcription. (781 aa)
araf-2MGC68526 protein. (643 aa)
hrasSmall G-protein H-Ras. (189 aa)
kras-3LOC397771 protein. (186 aa)
c-JunC-Jun protein; Belongs to the bZIP family. (312 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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