93 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	calcoco2	C2H2-type domain-containing protein. (454 aa)
	csnk2a1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (402 aa)
	A0A1L8EM88	Uncharacterized protein. (445 aa)
	Nbr1.S	Uncharacterized protein. (965 aa)
	e2f1	E2F_TDP domain-containing protein. (427 aa)
	A0A1L8ENK9	Uncharacterized protein. (208 aa)
	Atg9a.S	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (832 aa)
	Rhot2.S	Uncharacterized protein. (605 aa)
	A0A1L8ES53	C2H2-type domain-containing protein. (476 aa)
	A0A1L8ETC2	BH4_2 domain-containing protein. (212 aa)
	A0A1L8ETF4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	A0A1L8ETL4	APG6 domain-containing protein. (271 aa)
	Nbr1.L	Uncharacterized protein. (969 aa)
	Atg9a.L	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (832 aa)
	rhot2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (617 aa)
	tfe3	BHLH domain-containing protein. (513 aa)
	Hif-1a	Uncharacterized protein. (800 aa)
	A0A1L8F1U3	Uncharacterized protein. (199 aa)
	Tfe3.L	BHLH domain-containing protein. (517 aa)
	csnk2b	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	gabarapl1	Uncharacterized protein. (117 aa)
	mapk10	Mitogen-activated protein kinase. (426 aa)
	mfn2	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (756 aa)
	A0A1L8FGY5	Uncharacterized protein. (242 aa)
	kras	Uncharacterized protein. (186 aa)
	A0A1L8FH43	Rab-GAP TBC domain-containing protein. (672 aa)
	bnip3	Uncharacterized protein. (196 aa)
	A0A1L8FNE8	Rab-GAP TBC domain-containing protein. (828 aa)
	tax1bp1	Uncharacterized protein. (838 aa)
	Tomm7.L	Uncharacterized protein. (100 aa)
	foxo3	Fork-head domain-containing protein. (656 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	cited2	Uncharacterized protein. (225 aa)
	Foxo3.L	Fork-head domain-containing protein. (661 aa)
	mfn1	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (738 aa)
	rela	RHD_dimer domain-containing protein. (309 aa)
	ambra1	WD_REPEATS_REGION domain-containing protein. (1304 aa)
	rras2	Uncharacterized protein. (198 aa)
	A0A1L8GF13	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (349 aa)
	A0A1L8GF62	Uncharacterized protein. (150 aa)
	Atf4.S	BZIP domain-containing protein. (342 aa)
	A0A1L8GID1	Uncharacterized protein. (229 aa)
	rela-2	RHD domain-containing protein. (527 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	Atf4.L	BZIP domain-containing protein. (343 aa)
	usp8	Uncharacterized protein; Belongs to the peptidase C19 family. (1060 aa)
	Tbc1d15.S	Rab-GAP TBC domain-containing protein. (587 aa)
	tbk1	Protein kinase domain-containing protein. (725 aa)
	tbc1d15	Rab-GAP TBC domain-containing protein. (667 aa)
	usp15-2	Ubiquitin carboxyl-terminal hydrolase. (983 aa)
	Optn.L	CCHC NOA-type domain-containing protein. (570 aa)
	usp8-2	Uncharacterized protein; Belongs to the peptidase C19 family. (1063 aa)
	Fis1.L	TPR_REGION domain-containing protein. (207 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	Fundc1.S	Uncharacterized protein. (177 aa)
	tfeb	BHLH domain-containing protein. (435 aa)
	rab7b	Uncharacterized protein. (201 aa)
	sp1	Uncharacterized protein. (732 aa)
	nras	Uncharacterized protein. (189 aa)
	Fundc1-b	Uncharacterized protein. (150 aa)
	sp1-2	Uncharacterized protein. (722 aa)
	eif2ak3	Protein kinase domain-containing protein. (1091 aa)
	Pgam5.S	Uncharacterized protein. (275 aa)
	Ulk1.S	Protein kinase domain-containing protein. (967 aa)
	ubc	Uncharacterized protein. (533 aa)
	A0A1L8HT45	Protein kinase domain-containing protein. (1127 aa)
	mapk10-2	Mitogen-activated protein kinase. (444 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	Usp30.L	USP domain-containing protein; Belongs to the peptidase C19 family. (454 aa)
	pgam5	Uncharacterized protein. (279 aa)
	ulk1	Protein kinase domain-containing protein. (1049 aa)
	e2f1-2	LOC100036852 protein. (426 aa)
	optn	LOC100036954 protein. (526 aa)
	tax1bp1-2	Tax1 binding protein 1. (840 aa)
	src	Tyrosine-protein kinase. (532 aa)
	bnip3l	Bnip3l protein. (196 aa)
	mfn1-2	LOC495314 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (738 aa)
	krasl	Uncharacterized protein. (187 aa)
	kras-2	Uncharacterized protein. (187 aa)
	rab7a	Rab7-prov protein. (207 aa)
	rps27a	MGC81889 protein. (156 aa)
	rab7b-2	MGC80651 protein. (201 aa)
	MGC80266	MGC80266 protein. (208 aa)
	csnk2a2	MGC83125 protein; Belongs to the protein kinase superfamily. (349 aa)
	mfn2-2	MGC81251 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (756 aa)
	rab7a-2	MGC68523 protein. (207 aa)
	bnip3-2	MGC68574 protein. (202 aa)
	sqstm1	MGC64432 protein. (454 aa)
	hif1a	Hif1a-prov protein. (802 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	hras	Small G-protein H-Ras. (189 aa)
	kras-3	LOC397771 protein. (186 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EM88	A0A1L8ETC2	A0A1L8EM88	A0A1L8ETC2	Uncharacterized protein.	BH4_2 domain-containing protein.	0.984
A0A1L8EM88	A0A1L8ETL4	A0A1L8EM88	A0A1L8ETL4	Uncharacterized protein.	APG6 domain-containing protein.	0.900
A0A1L8EM88	A0A1L8GF62	A0A1L8EM88	A0A1L8GF62	Uncharacterized protein.	Uncharacterized protein.	0.969
A0A1L8EM88	Atg9a.L	A0A1L8EM88	A0A1L8EVK9	Uncharacterized protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.742
A0A1L8EM88	Atg9a.S	A0A1L8EM88	A0A1L8ENR0	Uncharacterized protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.742
A0A1L8EM88	Foxo3.L	A0A1L8EM88	A0A1L8G9I8	Uncharacterized protein.	Fork-head domain-containing protein.	0.402
A0A1L8EM88	Nbr1.L	A0A1L8EM88	A0A1L8ETV5	Uncharacterized protein.	Uncharacterized protein.	0.604
A0A1L8EM88	Nbr1.S	A0A1L8EM88	A0A1L8EMC4	Uncharacterized protein.	Uncharacterized protein.	0.604
A0A1L8EM88	Tp53.L	A0A1L8EM88	A0A1L8H4M6	Uncharacterized protein.	P53 domain-containing protein.	0.591
A0A1L8EM88	Ulk1.S	A0A1L8EM88	A0A1L8HQH7	Uncharacterized protein.	Protein kinase domain-containing protein.	0.989
A0A1L8EM88	ambra1	A0A1L8EM88	A0A1L8GDL3	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.997
A0A1L8EM88	bnip3	A0A1L8EM88	A0A1L8FJ19	Uncharacterized protein.	Uncharacterized protein.	0.708
A0A1L8EM88	bnip3-2	A0A1L8EM88	Q6PAX4	Uncharacterized protein.	MGC68574 protein.	0.708
A0A1L8EM88	foxo3	A0A1L8EM88	A0A1L8G307	Uncharacterized protein.	Fork-head domain-containing protein.	0.452
A0A1L8EM88	gabarapl1	A0A1L8EM88	A0A1L8FEA0	Uncharacterized protein.	Uncharacterized protein.	0.989
A0A1L8EM88	sqstm1	A0A1L8EM88	Q6PGS1	Uncharacterized protein.	MGC64432 protein.	0.789
A0A1L8EM88	tfeb	A0A1L8EM88	A0A1L8H6Y2	Uncharacterized protein.	BHLH domain-containing protein.	0.695
A0A1L8EM88	ulk1	A0A1L8EM88	A0A1L8I0T1	Uncharacterized protein.	Protein kinase domain-containing protein.	0.989
A0A1L8ES53	A0A1L8GF62	A0A1L8ES53	A0A1L8GF62	C2H2-type domain-containing protein.	Uncharacterized protein.	0.970
A0A1L8ES53	Atg9a.L	A0A1L8ES53	A0A1L8EVK9	C2H2-type domain-containing protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.422