STRINGSTRING
fzd2 fzd2 A0A1L8ELA2 A0A1L8ELA2 Gnas.S Gnas.S A0A1L8ENA1 A0A1L8ENA1 A0A1L8ENI2 A0A1L8ENI2 wnt10a wnt10a fzd5 fzd5 A0A1L8EPZ4 A0A1L8EPZ4 A0A1L8EQN9 A0A1L8EQN9 crebbp crebbp A0A1L8EQT4 A0A1L8EQT4 A0A1L8ES96 A0A1L8ES96 wnt9b.2 wnt9b.2 A0A1L8ESG7 A0A1L8ESG7 A0A1L8EVB6 A0A1L8EVB6 wnt6 wnt6 fzd7 fzd7 A0A1L8EX51 A0A1L8EX51 A0A1L8EX74 A0A1L8EX74 A0A1L8EYD3 A0A1L8EYD3 crebbp-2 crebbp-2 Adcy9.L Adcy9.L A0A1L8F1K1 A0A1L8F1K1 Ednrb2.S Ednrb2.S creb3l4 creb3l4 wnt11b wnt11b ednrb2 ednrb2 plcb2 plcb2 creb3l4-2 creb3l4-2 A0A1L8FDR5 A0A1L8FDR5 Camk2g.S Camk2g.S wnt4 wnt4 kras kras A0A1L8FHC4 A0A1L8FHC4 Tcf7l2.L Tcf7l2.L A0A1L8FJW6 A0A1L8FJW6 A0A1L8FJZ5 A0A1L8FJZ5 dvl1 dvl1 A0A1L8FPX8 A0A1L8FPX8 A0A1L8FPY5 A0A1L8FPY5 A0A1L8FQX7 A0A1L8FQX7 Fzd6.S Fzd6.S adcy8 adcy8 Wnt9a.S Wnt9a.S wnt3a wnt3a Fzd8.L Fzd8.L fzd1 fzd1 adcy1 adcy1 fzd6 fzd6 A0A1L8G048 A0A1L8G048 Plcb1.S Plcb1.S plcb4 plcb4 A0A1L8G423 A0A1L8G423 A0A1L8G5C7 A0A1L8G5C7 fzd3 fzd3 pomc pomc plcb4-2 plcb4-2 calm1 calm1 A0A1L8G603 A0A1L8G603 Dvl3.L Dvl3.L adcy3 adcy3 Pomc.L Pomc.L A0A1L8GF34 A0A1L8GF34 prkacb prkacb ep300 ep300 creb3l1 creb3l1 Plcb3.L Plcb3.L Adcy7.L Adcy7.L A0A1L8GKP7 A0A1L8GKP7 Prkacb.S Prkacb.S ep300-2 ep300-2 A0A1L8GPA9 A0A1L8GPA9 creb3l2 creb3l2 Wnt5b.S Wnt5b.S tcf7l1 tcf7l1 map2k1 map2k1 calml4 calml4 gnai1 gnai1 wnt16 wnt16 A0A1L8GU52 A0A1L8GU52 Kitlg.S Kitlg.S A0A1L8GVI0 A0A1L8GVI0 A0A1L8GYV6 A0A1L8GYV6 wnt16-2 wnt16-2 map2k1-2 map2k1-2 calml4-2 calml4-2 A0A1L8H5Q6 A0A1L8H5Q6 fzd9 fzd9 ednrb ednrb Adcy6.L Adcy6.L A0A1L8H9H5 A0A1L8H9H5 wnt1 wnt1 tyr tyr Fzd4.S Fzd4.S fzd9-2 fzd9-2 nras nras dct dct ednrb-2 ednrb-2 Wnt1.L Wnt1.L wnt10b wnt10b A0A1L8HHS4 A0A1L8HHS4 A0A1L8HJF4 A0A1L8HJF4 wnt11 wnt11 Kit.S Kit.S lef1 lef1 tyrp1 tyrp1 A0A1L8HPT0 A0A1L8HPT0 mapk1 mapk1 fzd10 fzd10 Kit.L Kit.L adcy4 adcy4 Mapk1.L Mapk1.L G67.L G67.L A0A310U820 A0A310U820 Adcy1.S Adcy1.S Creb3.S Creb3.S wnt6-2 wnt6-2 tcf7l1-2 tcf7l1-2 Xwnt-8b Xwnt-8b fzd10a fzd10a fz3 fz3 wnt10a-2 wnt10a-2 xfz8 xfz8 LOC397896 LOC397896 wnt7b wnt7b edn1 edn1 krasl krasl ctnnb1 ctnnb1 gnaq gnaq kras-2 kras-2 prkca prkca Q6DJF2_XENLA Q6DJF2_XENLA ctnnb1-2 ctnnb1-2 gnai3 gnai3 kitlg kitlg tyrp1-2 tyrp1-2 creb1 creb1 hras hras prkaca prkaca lef1-2 lef1-2 kras-3 kras-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fzd2Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
A0A1L8ELA2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
Gnas.SUncharacterized protein. (217 aa)
A0A1L8ENA1Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)
A0A1L8ENI2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1194 aa)
wnt10aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
A0A1L8EPZ4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
A0A1L8EQN9Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1306 aa)
crebbpUncharacterized protein. (2424 aa)
A0A1L8EQT4Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
A0A1L8ES96Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (554 aa)
wnt9b.2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
A0A1L8ESG7Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
A0A1L8EVB6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1194 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
fzd7Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
A0A1L8EX51Uncharacterized protein. (327 aa)
A0A1L8EX74Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
A0A1L8EYD3Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
crebbp-2Uncharacterized protein. (2453 aa)
Adcy9.LUncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1306 aa)
A0A1L8F1K1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
Ednrb2.SG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (435 aa)
creb3l4BZIP domain-containing protein. (434 aa)
wnt11bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ednrb2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (433 aa)
plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1258 aa)
creb3l4-2BZIP domain-containing protein. (458 aa)
A0A1L8FDR5HMG box domain-containing protein. (482 aa)
Camk2g.SProtein kinase domain-containing protein. (662 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
krasUncharacterized protein. (186 aa)
A0A1L8FHC4Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
Tcf7l2.LHMG box domain-containing protein. (482 aa)
A0A1L8FJW6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (431 aa)
A0A1L8FJZ5Protein kinase domain-containing protein. (654 aa)
dvl1Uncharacterized protein. (606 aa)
A0A1L8FPX8Uncharacterized protein. (461 aa)
A0A1L8FPY5Uncharacterized protein. (443 aa)
A0A1L8FQX7Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
Fzd6.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1240 aa)
Wnt9a.SProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (528 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
Fzd8.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
fzd1Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
adcy1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1116 aa)
fzd6Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
A0A1L8G048Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1240 aa)
Plcb1.S1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1213 aa)
plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1205 aa)
A0A1L8G423Uncharacterized protein. (711 aa)
A0A1L8G5C7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
fzd3Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
pomcUncharacterized protein. (260 aa)
plcb4-21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1205 aa)
calm1Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
A0A1L8G603Phosphoinositide phospholipase C. (1152 aa)
Dvl3.LUncharacterized protein. (745 aa)
adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
Pomc.LUncharacterized protein. (282 aa)
A0A1L8GF34Melanocyte-stimulating hormone receptor. (317 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
ep300Uncharacterized protein. (2495 aa)
creb3l1BZIP domain-containing protein. (474 aa)
Plcb3.L1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1210 aa)
Adcy7.LGuanylate cyclase domain-containing protein. (400 aa)
A0A1L8GKP7Uncharacterized protein. (354 aa)
Prkacb.SUncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
ep300-2Uncharacterized protein. (2492 aa)
A0A1L8GPA9Uncharacterized protein. (440 aa)
creb3l2BZIP domain-containing protein. (525 aa)
Wnt5b.SProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
tcf7l1HMG box domain-containing protein. (551 aa)
map2k1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
calml4Uncharacterized protein. (153 aa)
gnai1Uncharacterized protein. (354 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
A0A1L8GU52Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)
Kitlg.SKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (270 aa)
A0A1L8GVI0Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
A0A1L8GYV6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
wnt16-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
map2k1-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
calml4-2Uncharacterized protein. (152 aa)
A0A1L8H5Q6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
fzd9Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
ednrbG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (431 aa)
Adcy6.LUncharacterized protein. (1327 aa)
A0A1L8H9H5Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
tyrUncharacterized protein. (532 aa)
Fzd4.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
fzd9-2Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
nrasUncharacterized protein. (189 aa)
dctUncharacterized protein. (520 aa)
ednrb-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (431 aa)
Wnt1.LProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
A0A1L8HHS4Uncharacterized protein. (1302 aa)
A0A1L8HJF4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (456 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
Kit.SMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
lef1HMG box domain-containing protein. (372 aa)
tyrp1Uncharacterized protein. (534 aa)
A0A1L8HPT0Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1025 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
fzd10Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
Kit.LMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
Mapk1.LMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
G67.LUncharacterized protein. (718 aa)
A0A310U820Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
Adcy1.SAC_N domain-containing protein. (253 aa)
Creb3.SBZIP domain-containing protein. (446 aa)
wnt6-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
tcf7l1-2Transcription factor XTCF-3b. (554 aa)
Xwnt-8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
fzd10aFrizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
fz3Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
wnt10a-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
xfz8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
LOC397896G protein alpha subunit. (354 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
edn1LOC100158354 protein. (221 aa)
kraslUncharacterized protein. (187 aa)
ctnnb1Beta-catenin protein. (781 aa)
gnaqGnaq-A protein. (359 aa)
kras-2Uncharacterized protein. (187 aa)
prkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
Q6DJF2_XENLAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
ctnnb1-2Ctnnb1-prov protein. (781 aa)
gnai3MGC53612 protein. (354 aa)
kitlgKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (270 aa)
tyrp1-2Tyrp1-prov protein. (534 aa)
creb1Creb1-prov protein. (324 aa)
hrasSmall G-protein H-Ras. (189 aa)
prkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
lef1-2Lymphoid enhancer factor XLEF-1. (372 aa)
kras-3LOC397771 protein. (186 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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