(7 nodes) Mixed, incl. Tissue factor, and Interferon binding network (Xenopus tropicalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ifnar2.1	Fibronectin type-III domain-containing protein. (498 aa)
	ifngr2.2	Lactamase beta. (337 aa)
	TYK2	Tyrosine-protein kinase. (1195 aa)
	LOC105945198	Type I interferon 4. (189 aa)
	ifngr2.1	Uncharacterized protein. (311 aa)
	ifnar1	Uncharacterized protein. (642 aa)
	ifngr1	Uncharacterized protein. (433 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC105945198	ifnar1	ENSXETP00000010077	ENSXETP00000026732	Type I interferon 4.	Uncharacterized protein.	0.924
LOC105945198	ifnar2.1	ENSXETP00000010077	ENSXETP00000005552	Type I interferon 4.	Fibronectin type-III domain-containing protein.	0.935
LOC105945198	ifngr1	ENSXETP00000010077	ENSXETP00000035085	Type I interferon 4.	Uncharacterized protein.	0.910
LOC105945198	ifngr2.1	ENSXETP00000010077	ENSXETP00000026685	Type I interferon 4.	Uncharacterized protein.	0.904
LOC105945198	ifngr2.2	ENSXETP00000010077	ENSXETP00000005628	Type I interferon 4.	Lactamase beta.	0.904
TYK2	ifnar1	ENSXETP00000008181	ENSXETP00000026732	Tyrosine-protein kinase.	Uncharacterized protein.	0.978
TYK2	ifnar2.1	ENSXETP00000008181	ENSXETP00000005552	Tyrosine-protein kinase.	Fibronectin type-III domain-containing protein.	0.947
TYK2	ifngr1	ENSXETP00000008181	ENSXETP00000035085	Tyrosine-protein kinase.	Uncharacterized protein.	0.764
TYK2	ifngr2.1	ENSXETP00000008181	ENSXETP00000026685	Tyrosine-protein kinase.	Uncharacterized protein.	0.762
TYK2	ifngr2.2	ENSXETP00000008181	ENSXETP00000005628	Tyrosine-protein kinase.	Lactamase beta.	0.762
ifnar1	LOC105945198	ENSXETP00000026732	ENSXETP00000010077	Uncharacterized protein.	Type I interferon 4.	0.924
ifnar1	TYK2	ENSXETP00000026732	ENSXETP00000008181	Uncharacterized protein.	Tyrosine-protein kinase.	0.978
ifnar1	ifnar2.1	ENSXETP00000026732	ENSXETP00000005552	Uncharacterized protein.	Fibronectin type-III domain-containing protein.	0.995
ifnar1	ifngr1	ENSXETP00000026732	ENSXETP00000035085	Uncharacterized protein.	Uncharacterized protein.	0.974
ifnar1	ifngr2.1	ENSXETP00000026732	ENSXETP00000026685	Uncharacterized protein.	Uncharacterized protein.	0.936
ifnar1	ifngr2.2	ENSXETP00000026732	ENSXETP00000005628	Uncharacterized protein.	Lactamase beta.	0.949
ifnar2.1	LOC105945198	ENSXETP00000005552	ENSXETP00000010077	Fibronectin type-III domain-containing protein.	Type I interferon 4.	0.935
ifnar2.1	TYK2	ENSXETP00000005552	ENSXETP00000008181	Fibronectin type-III domain-containing protein.	Tyrosine-protein kinase.	0.947
ifnar2.1	ifnar1	ENSXETP00000005552	ENSXETP00000026732	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.995
ifnar2.1	ifngr1	ENSXETP00000005552	ENSXETP00000035085	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.933

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