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| | sirt7 | Deacetylase sirtuin-type domain-containing protein. (408 aa) |
| | LOC100485680 | Chromosome 3 open reading frame 49. (260 aa) |
| | LOC100127789 | Prolyl 4-hydroxylase, alpha polypeptide 1. (266 aa) |
| | LOC548368 | Uncharacterized protein. (248 aa) |
| | entpd5 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (428 aa) |
| | top3a-2 | DNA topoisomerase III alpha. (278 aa) |
| | nme3 | SRY-box 8; Belongs to the NDK family. (188 aa) |
| | nme2 | Nucleoside diphosphate kinase. (204 aa) |
| | dpep1 | Solute carrier family 25 member 43. (409 aa) |
| | nt5c2 | Cytosolic purine 5'-nucleotidase; May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides (By similarity). (638 aa) |
| | nadk | Uncharacterized protein. (448 aa) |
| | nudt1 | Leucine rich repeat and fibronectin type III domain containing 3; Belongs to the Nudix hydrolase family. (156 aa) |
| | nudt18 | Protein phosphatase 1 regulatory subunit 3B. (329 aa) |
| | nt5c1a | Uncharacterized protein. (430 aa) |
| | nkrf-2 | NFKB repressing factor. (97 aa) |
| | adarb2 | A to I editase domain-containing protein. (123 aa) |
| | Uckl1 | Uncharacterized protein. (176 aa) |
| | uck2 | Uridine-cytidine kinase 2; Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor (By similarity). (261 aa) |
| | sirt4 | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (322 aa) |
| | ephx2 | Epoxide hydrolase 2, cytoplasmic. (560 aa) |
| | ada | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (359 aa) |
| | ada.2 | A_deaminase domain-containing protein. (415 aa) |
| | impdh1 | Inosine-5'-monophosphate dehydrogenase 1; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (596 aa) |
| | GMPS | Guanine monophosphate synthase. (763 aa) |
| | guk1 | EF-hand calcium-binding domain 7. (233 aa) |
| | LOC100145000 | ELF1 homolog, elongation factor 1. (322 aa) |
| | dctpp1 | dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (158 aa) |
| | LOC101734368 | RNA pseudouridylate synthase domain containing 2. (107 aa) |
| | nmnat2 | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate (By similarity). Belongs to the eukaryotic NMN adenylyltransferase family. (307 aa) |
| | entpd2 | Mitogen-activated protein kinase 8 interacting protein 2; Belongs to the GDA1/CD39 NTPase family. (484 aa) |
| | ctps2 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (599 aa) |
| | SIRT3 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (358 aa) |
| | LOC100127826 | Thromboxane A synthase 1. (261 aa) |
| | cmpk1 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (219 aa) |
| | manea | Syntaxin binding protein 1. (449 aa) |
| | ak5 | Uncharacterized protein; Belongs to the adenylate kinase family. (557 aa) |
| | nadk2 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor (By similarity). (427 aa) |
| | dck.1 | Dck protein. (265 aa) |
| | nnt | LRAT domain containing 1. (1086 aa) |
| | adsl | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (513 aa) |
| | nt5c3a | 5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (334 aa) |
| | dctd | CMP/dCMP-type deaminase domain-containing protein. (190 aa) |
| | isoc1 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. (310 aa) |
| | rrm2b | Uncharacterized protein. (416 aa) |
| | LOC100485794 | PfkB domain-containing protein. (720 aa) |
| | Cda | Cytidine deaminase. (118 aa) |
| | upp1 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (311 aa) |
| | cmpk2 | Tripartite motif containing 2. (459 aa) |
| | sirt6 | Sirtuin (Silent mating type information regulation 2 homolog) 6. (331 aa) |
| | LOC100145174 | LOC100145174 protein. (260 aa) |
| | ADA2 | Adenosine deaminase 2. (424 aa) |
| | DGUOK | Deoxyguanosine kinase. (265 aa) |
| | sirt5 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (309 aa) |
| | nudt5 | Nudix (Nucleoside diphosphate linked moiety x) type motif 5; Belongs to the Nudix hydrolase family. (221 aa) |
| | LOC100496844 | Glyoxylate reductase/hydroxypyruvate reductase, gene 2. (261 aa) |
| | LOC594886 | Uncharacterized protein. (266 aa) |
| | LOC100496871 | Uncharacterized protein. (266 aa) |
| | LOC100491286 | Uncharacterized protein. (259 aa) |
| | ctps1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (602 aa) |
| | adssl1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. Belongs to the adenylosuccinate synthetase family. (468 aa) |
| | ampd3 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (782 aa) |
| | nt5c3b | 5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (290 aa) |
| | hexb-2 | Hexosaminidase B (beta polypeptide). (176 aa) |
| | pde7b | Phosphodiesterase. (506 aa) |
| | entpd3 | Progesterone receptor membrane component 1; Belongs to the GDA1/CD39 NTPase family. (510 aa) |
| | SIRT2 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (414 aa) |
| | hddc3 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1; ppGpp hydrolyzing enzyme involved in starvation response. (179 aa) |
| | sirt3.2 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (401 aa) |
| | nadsyn1 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (733 aa) |
| | ak2 | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (235 aa) |
| | nmrk1 | Uncharacterized protein. (198 aa) |
| | ENSXETP00000027777 | FRAS1 related extracellular matrix 1b. (137 aa) |
| | LOC101733556 | Sorcin. (303 aa) |
| | cd38 | Fc receptor, IgG, high affinity I. (300 aa) |
| | NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (582 aa) |
| | nt5m | Potassium channel, voltage gated shaker related subfamily A, member 1. (227 aa) |
| | ak1 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (502 aa) |
| | pnp | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (297 aa) |
| | AMPD1 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (771 aa) |
| | tk1 | Thymidine kinase. (262 aa) |
| | naprt | Zinc finger protein 33A. (216 aa) |
| | ENTPD6 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (469 aa) |
| | aprt | Adenine phosphoribosyltransferase. (180 aa) |
| | adat2 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. (175 aa) |
| | cant1 | Calcium activated nucleotidase 1. (400 aa) |
| | dck.2 | Dpy-19-like 4. (265 aa) |
| | UCK1 | Uridine-cytidine kinase; Belongs to the uridine kinase family. (292 aa) |
| | LOC548390 | LOC548390 protein. (322 aa) |
| | entpd8 | Forkhead box protein C2; Belongs to the GDA1/CD39 NTPase family. (478 aa) |
| | QPRT | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (302 aa) |
| | tk2 | Kinectin 1. (279 aa) |
| | gda | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (478 aa) |
| | LOC100492724 | Pim-3 proto-oncogene, serine/threonine kinase. (261 aa) |
| | MGC88898 | Uncharacterized protein. (261 aa) |
| | LOC100492223 | Solute carrier family 35 member F2. (261 aa) |
| | c11orf65-2 | Chromosome 11 open reading frame 65. (143 aa) |
| | LOC100497323 | Probable sodium-coupled neutral amino acid transporter 6. (261 aa) |
| | LOC100497161 | Uncharacterized protein. (261 aa) |
| | upp2 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (316 aa) |
| | LOC101733847 | Obscurin-like 1. (261 aa) |
| | LOC100485981 | Uncharacterized loc548369. (261 aa) |
| | ampd2 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (831 aa) |
| | ITPA | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (194 aa) |
| | prps1 | Pribosyltran_N domain-containing protein. (322 aa) |
| | nmnat1 | Nicotinamide-nucleotide adenylyltransferase. (320 aa) |
| | AK9 | Adenylate kinase 9. (1609 aa) |
| | hlcs | Engrailed homeobox 2. (853 aa) |
| | slc22a16 | Coiled-coil domain containing 30. (566 aa) |
| | gmpr2 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (381 aa) |
| | LOC100145149 | Fatty acid binding protein 3. (245 aa) |
| | nudt4 | Nudix (Nucleoside diphosphate linked moiety X)-type motif 4. (180 aa) |
| | tymp | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (513 aa) |
| | nme6 | Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (179 aa) |
| | adarb1 | Solute carrier family 45 member 3. (719 aa) |
| | ENSXETP00000038817 | L27_1 domain-containing protein. (59 aa) |
| | prps2 | Ribose-phosphate pyrophosphokinase 2; Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis; Belongs to the ribose-phosphate pyrophosphokinase family. (318 aa) |
| | entpd1 | NEDD4 binding protein 2-like 1; Belongs to the GDA1/CD39 NTPase family. (536 aa) |
| | nudt16 | Solute carrier family 45 member 2. (213 aa) |
| | PDE1C | Phosphodiesterase. (710 aa) |
| | NUDT15 | Nudix hydrolase 15. (224 aa) |
| | nudt12 | Paired like homeobox 2B. (458 aa) |
| | dalrd3 | LIM homeobox 2. (574 aa) |
| | kiaa1614 | PDZ domain-containing protein. (1068 aa) |
| | rrm2.2 | Collagen, type VI, alpha 6. (447 aa) |
| | rrm2.1 | Uncharacterized protein. (397 aa) |
| | impdh2 | Inosine-5'-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (594 aa) |
| | qrich1 | Glutamine-rich 1. (799 aa) |
| | ak6 | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (171 aa) |
| | uprt | Thiosulfate sulfurtransferase (rhodanese)-like domain containing 2. (291 aa) |
| | dtymk | Deoxythymidylate kinase (Thymidylate kinase). (216 aa) |
| | SLC44A3 | Solute carrier family 44 member 3; Belongs to the CTL (choline transporter-like) family. (661 aa) |
| | NT5C1A | 5'-nucleotidase, cytosolic IA. (364 aa) |
| | slc28a2 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (636 aa) |
| | rrm1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (786 aa) |
| | nampt | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (506 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (231 aa) |
| | pde1a | Phosphodiesterase. (541 aa) |
| | atic | MGS domain-containing protein. (607 aa) |
| | LOC734042 | IU_nuc_hydro domain-containing protein. (319 aa) |
| | SLC28A3 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (634 aa) |
| | adprm.2 | Potassium channel tetramerization domain containing 7. (337 aa) |
| | adprm | Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase; Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP- glucose. (348 aa) |
| | ak7 | Adenylate kinase 7. (710 aa) |
| | prtfdc1 | Phosphoribosyltransferase domain-containing protein 1; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (224 aa) |
| | adss | Adenylosuccinate synthetase isozyme 2 A; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. (477 aa) |
| | entpd4 | Novel protein similar to cornifelin; Belongs to the GDA1/CD39 NTPase family. (621 aa) |
| | sirt1 | Thrombospondin-type laminin G domain and EAR repeats. (707 aa) |
| | gmpr | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (363 aa) |
| | slc25a16 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa) |
| | pde11a | Uncharacterized protein. (892 aa) |
| | adk | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. (370 aa) |
| | btd | FA complementation group C. (507 aa) |
| | PDE7A | Phosphodiesterase. (467 aa) |
| | dpp4 | Uncharacterized protein; Belongs to the peptidase S9B family. (837 aa) |
| | ak3 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (221 aa) |
| | dut-2 | dUTPase domain-containing protein. (212 aa) |
| | LOC100490887 | GPN-loop GTPase 3. (1066 aa) |
| | nmrk2 | Uncharacterized protein. (233 aa) |
| | adal | A_deaminase domain-containing protein. (360 aa) |
| | nrf1 | Ribosomal RNA-processing 8. (556 aa) |
