node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AK4 | adk | ENSXETP00000046646 | ENSXETP00000051699 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | 0.934 |
AK4 | ak1 | ENSXETP00000046646 | ENSXETP00000028504 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | 0.919 |
AK4 | ak2 | ENSXETP00000046646 | ENSXETP00000026948 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. | 0.918 |
AK4 | ak5 | ENSXETP00000046646 | ENSXETP00000013162 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Uncharacterized protein; Belongs to the adenylate kinase family. | 0.929 |
AK4 | ak6 | ENSXETP00000046646 | ENSXETP00000043798 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. | 0.924 |
AK4 | ak7 | ENSXETP00000046646 | ENSXETP00000048249 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase 7. | 0.934 |
AK4 | ampd2 | ENSXETP00000046646 | ENSXETP00000035255 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.911 |
AK4 | pde11a | ENSXETP00000046646 | ENSXETP00000051634 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Uncharacterized protein. | 0.664 |
AK4 | pde7b | ENSXETP00000046646 | ENSXETP00000023903 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Phosphodiesterase. | 0.664 |
adk | AK4 | ENSXETP00000051699 | ENSXETP00000046646 | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | 0.934 |
adk | ak1 | ENSXETP00000051699 | ENSXETP00000028504 | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | 0.929 |
adk | ak2 | ENSXETP00000051699 | ENSXETP00000026948 | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. | 0.976 |
adk | ak5 | ENSXETP00000051699 | ENSXETP00000013162 | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | Uncharacterized protein; Belongs to the adenylate kinase family. | 0.918 |
adk | ak6 | ENSXETP00000051699 | ENSXETP00000043798 | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. | 0.915 |
adk | ak7 | ENSXETP00000051699 | ENSXETP00000048249 | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | Adenylate kinase 7. | 0.934 |
adk | ampd2 | ENSXETP00000051699 | ENSXETP00000035255 | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.954 |
adk | pde11a | ENSXETP00000051699 | ENSXETP00000051634 | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | Uncharacterized protein. | 0.918 |
adk | pde7b | ENSXETP00000051699 | ENSXETP00000023903 | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | Phosphodiesterase. | 0.944 |
ak1 | AK4 | ENSXETP00000028504 | ENSXETP00000046646 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | 0.919 |
ak1 | adk | ENSXETP00000028504 | ENSXETP00000051699 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. | 0.929 |