STRINGSTRING
sema4a sema4a TOPORS TOPORS nrl nrl klhl7 klhl7 LOC100496819 LOC100496819 PCARE PCARE usp16 usp16 ENSXETP00000036728 ENSXETP00000036728 pdxk-2 pdxk-2 CERKL CERKL nr2e3 nr2e3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sema4aSema domain-containing protein; Belongs to the semaphorin family. (681 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1018 aa)
nrlGolgi brefeldin A resistant guanine nucleotide exchange factor 1. (289 aa)
klhl7BTB domain-containing protein. (587 aa)
LOC100496819LUC7-like. (257 aa)
PCAREPhotoreceptor cilium actin regulator. (1164 aa)
usp16Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (864 aa)
ENSXETP00000036728RING-type domain-containing protein. (85 aa)
pdxk-2Adenosylhomocysteinase. (1680 aa)
CERKLCeramide kinase like. (643 aa)
nr2e3Uncharacterized protein. (409 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.