STRINGSTRING
ADCY1 ADCY1 pik3r6 pik3r6 gngt2.1 gngt2.1 gnat2-2 gnat2-2 gng7 gng7 gna11 gna11 gng5 gng5 pde9a pde9a pde4a pde4a VWA1 VWA1 RAPGEF4 RAPGEF4 gnaz gnaz gng3 gng3 pde2a pde2a LOC101731365 LOC101731365 gna15-2 gna15-2 plcb4 plcb4 gng10 gng10 pik3r5 pik3r5 gng13 gng13 DRD2 DRD2 ADCY6 ADCY6 ADCY9 ADCY9 gnas gnas adcy4 adcy4 ptrhd1 ptrhd1 pde4c pde4c LOC101734573 LOC101734573 gnb4 gnb4 tcf4 tcf4 gnai3 gnai3 gna14 gna14 gng2 gng2 adcy7 adcy7 trim32 trim32 srsf7-2 srsf7-2 prkce prkce ENSXETP00000041957 ENSXETP00000041957 LOC100490464 LOC100490464 PDE10A PDE10A poc1b poc1b pik3cg pik3cg usp47 usp47 pde4b pde4b ENSXETP00000049648 ENSXETP00000049648 gngt2 gngt2 wnk3 wnk3 gnao1 gnao1 PDE4D PDE4D gnai1 gnai1 gnb5 gnb5 birc5 birc5 PLCB2 PLCB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
pik3r6POU class 6 homeobox 2. (739 aa)
gngt2.1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
gnat2-2Serine protease 12. (99 aa)
gng7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
gna11Guanine nucleotide binding protein (G protein), alpha 11 (Gq class). (359 aa)
gng5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
pde9aChromosome 16 open reading frame 72; Belongs to the cyclic nucleotide phosphodiesterase family. (344 aa)
pde4aPhosphodiesterase. (690 aa)
VWA1Von Willebrand factor A domain containing 1. (496 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1024 aa)
gnazCCR4-NOT transcription complex subunit 9. (355 aa)
gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
pde2aUncharacterized protein. (594 aa)
LOC101731365Nucleolus and neural progenitor protein. (303 aa)
gna15-2Cleavage and polyadenylation specific factor 6. (213 aa)
plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1205 aa)
gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
pik3r5Phosphoinositide-3-kinase, regulatory subunit 5, p101. (877 aa)
gng13Guanine nucleotide binding protein (G protein), gamma 13. (67 aa)
DRD2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (440 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1295 aa)
gnasATPase family AAA domain-containing protein 1. (292 aa)
adcy4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
ptrhd1Inactive serine protease PAMR1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (915 aa)
pde4cPhosphodiesterase. (801 aa)
LOC101734573Myocardial zonula adherens protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (132 aa)
gnb4LOC549706 protein. (327 aa)
tcf4BHLH domain-containing protein. (660 aa)
gnai3Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
gna14Guanine nucleotide binding protein (G protein), alpha 14. (354 aa)
gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (145 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1061 aa)
trim32LOC100124994 protein. (649 aa)
srsf7-2Proline-rich coiled-coil 2C. (410 aa)
prkceProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (779 aa)
ENSXETP00000041957Phosphodiesterase 9A; Belongs to the cyclic nucleotide phosphodiesterase family. (247 aa)
LOC100490464WD repeat domain 41; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (843 aa)
PDE10APhosphodiesterase. (818 aa)
poc1bPOC1 centriolar protein homolog B; Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Belongs to the WD repeat POC1 family. (470 aa)
pik3cgUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1123 aa)
usp47Ubiquitin carboxyl-terminal hydrolase 47; Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (polb), stabilizing polb thereby playing a role in base-excision repair (BER). (1354 aa)
pde4bPhosphodiesterase. (733 aa)
ENSXETP00000049648Uncharacterized protein. (260 aa)
gngt2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
wnk3Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
gnao1Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O. (354 aa)
PDE4DPhosphodiesterase. (719 aa)
gnai1Uncharacterized protein. (397 aa)
gnb5TATA-box binding protein associated factor 13. (395 aa)
birc5Baculoviral IAP repeat-containing protein 5.1. (899 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1250 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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