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dlc | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa) | ||||
dll1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (740 aa) | ||||
notch1 | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2535 aa) | ||||
NOTCH3 | Notch receptor 3. (2413 aa) | ||||
DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (679 aa) |