STRINGSTRING
LOC100145442 LOC100145442 nell2 nell2 GLG1 GLG1 nmt2 nmt2 loxl4 loxl4 RNFT2 RNFT2 scnn1a scnn1a lman2l lman2l atp13a1 atp13a1 ralgapa2 ralgapa2 mstn.2 mstn.2 mstn.1 mstn.1 enpp4 enpp4 ENSXETP00000018850 ENSXETP00000018850 znf280d znf280d tpbg-2 tpbg-2 tmem14c tmem14c nmt1 nmt1 acbd7 acbd7 BTBD11 BTBD11 FGR FGR c9orf64-2 c9orf64-2 LOC100489507 LOC100489507 prom1 prom1 MSTO1 MSTO1 tafa2 tafa2 adgrg1 adgrg1 arl8a arl8a COX20 COX20 hif1a-2 hif1a-2 SIK3 SIK3 slc11a1 slc11a1 FAM234B FAM234B tmem97 tmem97 abraxas1-2 abraxas1-2 vdac1-3 vdac1-3 LOC100497652 LOC100497652 efcab14 efcab14 elf2 elf2 hvcn1 hvcn1 samd15 samd15 cox16 cox16 TM9SF2 TM9SF2 robo3 robo3 stk10 stk10 cacna1e cacna1e acbd6 acbd6 pgrmc1 pgrmc1 palmd palmd PHF20L1 PHF20L1 acbd5 acbd5 lman2 lman2 tmem106b tmem106b loxl2 loxl2 dmbx1 dmbx1 adam9 adam9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100145442Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (217 aa)
nell2Protein kinase C-binding protein NELL2. (827 aa)
GLG1Golgi glycoprotein 1. (1148 aa)
nmt2Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (484 aa)
loxl4Cell division cycle 5 like. (731 aa)
RNFT2Ring finger protein, transmembrane 2. (457 aa)
scnn1aClaudin 16; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (632 aa)
lman2lL-type lectin-like domain-containing protein. (353 aa)
atp13a1Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1174 aa)
ralgapa2Rap-GAP domain-containing protein. (1889 aa)
mstn.2Ubiquitin associated protein 2. (374 aa)
mstn.1Lin-37 DREAM MuvB core complex component. (369 aa)
enpp4Bis(5'-adenosyl)-triphosphatase enpp4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. (452 aa)
ENSXETP00000018850SH2 domain-containing protein. (475 aa)
znf280dC2H2-type domain-containing protein. (829 aa)
tpbg-2Trophoblast glycoprotein. (121 aa)
tmem14cPannexin 1. (124 aa)
nmt1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (623 aa)
acbd7MGC146543 protein. (88 aa)
BTBD11BTB domain containing 11. (1019 aa)
FGRTyrosine-protein kinase. (522 aa)
c9orf64-2Queuosine salvage protein; Involved in salvaging queuosine. (341 aa)
LOC100489507Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (679 aa)
prom1Uncharacterized protein. (902 aa)
MSTO1Misato mitochondrial distribution and morphology regulator 1. (357 aa)
tafa2Golgi SNAP receptor complex member 1. (136 aa)
adgrg1Olfactory receptor. (316 aa)
arl8aADP-ribosylation factor-like protein 8A; May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation (By similarity); Belongs to the small GTPase superfamily. Arf family. (186 aa)
COX20Cytochrome c oxidase assembly factor COX20. (117 aa)
hif1a-2Caveolin 1. (183 aa)
SIK3SIK family kinase 3. (1284 aa)
slc11a1T-box 4. (340 aa)
FAM234BFamily with sequence similarity 234 member B. (618 aa)
tmem97Sigma intracellular receptor 2; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. (171 aa)
abraxas1-2BRCA1-A complex subunit Abraxas 1. (658 aa)
vdac1-3Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (614 aa)
LOC100497652Uncharacterized protein. (202 aa)
efcab14Insulin-induced gene 1 protein. (464 aa)
elf2Pleckstrin homology and RUN domain containing M2. (588 aa)
hvcn1Voltage-gated hydrogen channel 1; Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient (By similarity). (230 aa)
samd15Protein smg8. (132 aa)
cox16Uncharacterized protein. (107 aa)
TM9SF2Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (700 aa)
robo3Polymerase (RNA) I polypeptide A. (1424 aa)
stk10Serine/threonine-protein kinase 10; May act as a polo kinase kinase by mediating phosphorylation of plk1/plx1 and subsequent activation of plk1/plx1 during oocyte maturation; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (951 aa)
cacna1eVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2153 aa)
acbd6Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA. Does not bind fatty acids (By similarity). (286 aa)
pgrmc1Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (177 aa)
palmdInsulin like growth factor 2 receptor. (542 aa)
PHF20L1PHD finger protein 20 like 1. (889 aa)
acbd5Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity); Belongs to the ATG37 family. (469 aa)
lman2Centrosomal protein cep57l1. (344 aa)
tmem106bUncharacterized protein. (303 aa)
loxl2Lysyl oxidase homolog 2; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Shows no activity against histone H3 when it is trimethylated on 'Lys- 9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2). Also mediates deamination of methylated TAF10, a member o [...] (786 aa)
dmbx1Syntaxin 19. (367 aa)
adam9Polymerase (DNA) gamma, catalytic subunit. (863 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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