STRINGSTRING
afg3l1p afg3l1p spg7 spg7 cldn15.2 cldn15.2 fis1 fis1 marchf5 marchf5 opa1 opa1 stoml2 stoml2 phb2 phb2 dnm2 dnm2 rhbdf2 rhbdf2 dnm1l dnm1l mff mff mief2 mief2 parl parl stom stom oma1 oma1 mfn1 mfn1 rnpepl1-2 rnpepl1-2 DNM3 DNM3 afg3l2 afg3l2 pgam5 pgam5 ei24-2 ei24-2 rhbdl2 rhbdl2 ENSXETP00000045435 ENSXETP00000045435 mfn2 mfn2 yme1l1 yme1l1 hprt1 hprt1 phb phb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
afg3l1pFucosyltransferase 1 (H blood group). (785 aa)
spg7Tetraspanin 31. (768 aa)
cldn15.2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
fis1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (150 aa)
marchf5E3 ubiquitin-protein ligase XIAP. (283 aa)
opa1Cyclin-dependent kinase inhibitor 2B; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1010 aa)
stoml2PHB domain-containing protein. (341 aa)
phb2Prohibitin-2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging (By similarity); Belongs to the prohibitin family. (301 aa)
dnm2Discoidin, CUB and LCCL domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (881 aa)
rhbdf2Inactive rhomboid protein 2; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. Belongs to the peptidase S54 family. (839 aa)
dnm1lUncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (735 aa)
mffGlycosylphosphatidylinositol anchor attachment 1. (304 aa)
mief2Cytochrome P450 family 2 subfamily A member 13 like. (461 aa)
parlRhomboid domain-containing protein. (364 aa)
stomMyosin 10, gene 2. (303 aa)
oma1Transmembrane protein 19. (485 aa)
mfn1Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (756 aa)
rnpepl1-2Arginyl aminopeptidase (aminopeptidase B)-like 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (401 aa)
DNM3Dynamin 3. (310 aa)
afg3l2Uncharacterized protein. (808 aa)
pgam5Serine/threonine-protein phosphatase PGAM5, mitochondrial; Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics (By similarity). May be a central mediator for programmed necrosis (By similarity); Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (278 aa)
ei24-2Etoposide induced 2.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (879 aa)
rhbdl2Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (290 aa)
ENSXETP00000045435PHB domain-containing protein. (209 aa)
mfn2Small G protein signaling modulator 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (753 aa)
yme1l1Glycogen synthase 1. (742 aa)
hprt1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (224 aa)
phbProhibitin. (272 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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