(25 nodes) RNA polymerase, and Transcription factor TFIIIB complex network (Xenopus tropicalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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Predicted Interactions

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Your Input:
	polr3g	Uncharacterized protein. (192 aa)
	Maf1	Uncharacterized protein. (114 aa)
	polr3f	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (317 aa)
	polr3gl	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (215 aa)
	brf1	Neuronal PAS domain protein 3. (711 aa)
	polr3e	Uncharacterized protein. (701 aa)
	polr1e	Uncharacterized protein. (420 aa)
	crcp	RPOL4c domain-containing protein. (146 aa)
	polr3d	Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa. (394 aa)
	polr3h	Myeloid-associated differentiation marker-like 2. (227 aa)
	POLR1C	RNA polymerase I and III subunit C. (365 aa)
	polr3c	Nucleoside diphosphate-linked moiety X motif 17; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. (568 aa)
	polr3k	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
	polr3b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1142 aa)
	POLR1B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1141 aa)
	POLR1A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1698 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	cd3eap	Uncharacterized protein. (197 aa)
	polr1d.2	TIA1 cytotoxic granule-associated RNA binding protein-like 1. (128 aa)
	brf2	Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. (519 aa)
	bdp1	SANT domain-containing protein. (2372 aa)
	twistnb	Family with sequence similarity 222 member B. (471 aa)
	polr3a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1390 aa)
	RRN3	RRN3 homolog, RNA polymerase I transcription factor. (613 aa)
	ZNRD1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (122 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Maf1	POLR1A	ENSXETP00000011996	ENSXETP00000038347	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.805
Maf1	POLR1B	ENSXETP00000011996	ENSXETP00000035595	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.637
Maf1	POLR1C	ENSXETP00000011996	ENSXETP00000023206	Uncharacterized protein.	RNA polymerase I and III subunit C.	0.769
Maf1	RRN3	ENSXETP00000011996	ENSXETP00000053261	Uncharacterized protein.	RRN3 homolog, RNA polymerase I transcription factor.	0.453
Maf1	ZNRD1	ENSXETP00000011996	ENSXETP00000054853	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.435
Maf1	bdp1	ENSXETP00000011996	ENSXETP00000043147	Uncharacterized protein.	SANT domain-containing protein.	0.600
Maf1	brf1	ENSXETP00000011996	ENSXETP00000015307	Uncharacterized protein.	Neuronal PAS domain protein 3.	0.576
Maf1	brf2	ENSXETP00000011996	ENSXETP00000042918	Uncharacterized protein.	Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family.	0.576
Maf1	polr1d.2	ENSXETP00000011996	ENSXETP00000042125	Uncharacterized protein.	TIA1 cytotoxic granule-associated RNA binding protein-like 1.	0.662
Maf1	polr2h	ENSXETP00000011996	ENSXETP00000038644	Uncharacterized protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.459
Maf1	polr3a	ENSXETP00000011996	ENSXETP00000049485	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.941
Maf1	polr3b	ENSXETP00000011996	ENSXETP00000026459	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.923
Maf1	polr3c	ENSXETP00000011996	ENSXETP00000023293	Uncharacterized protein.	Nucleoside diphosphate-linked moiety X motif 17; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family.	0.883
Maf1	polr3d	ENSXETP00000011996	ENSXETP00000021999	Uncharacterized protein.	Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa.	0.809
Maf1	polr3e	ENSXETP00000011996	ENSXETP00000015914	Uncharacterized protein.	Uncharacterized protein.	0.869
Maf1	polr3f	ENSXETP00000011996	ENSXETP00000012978	Uncharacterized protein.	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.	0.872
Maf1	polr3g	ENSXETP00000011996	ENSXETP00000009269	Uncharacterized protein.	Uncharacterized protein.	0.608
Maf1	polr3gl	ENSXETP00000011996	ENSXETP00000014730	Uncharacterized protein.	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.	0.608
Maf1	polr3k	ENSXETP00000011996	ENSXETP00000024404	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.567
POLR1A	Maf1	ENSXETP00000038347	ENSXETP00000011996	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.805

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