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cenpu cenpu pax8-2 pax8-2 ndc80 ndc80 mis12 mis12 cenpo cenpo nsl1 nsl1 cenpm cenpm dsn1 dsn1 cenpc cenpc pmf1 pmf1 cenpt cenpt spc24 spc24 cenpi cenpi CENPW CENPW nuf2 nuf2 cenpn cenpn cenpl cenpl CENPK CENPK spc25 spc25 knl1 knl1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cenpuCentromere protein N. (531 aa)
pax8-2Uncharacterized protein. (294 aa)
ndc80Kinetochore protein NDC80 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores t [...] (640 aa)
mis12Uncharacterized protein. (221 aa)
cenpoCentromere protein O; Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation; Belongs to the CENP-O/MCM21 family. (330 aa)
nsl1Uncharacterized protein. (880 aa)
cenpmArachidonate 5-lipoxygenase. (199 aa)
dsn1Uncharacterized protein. (340 aa)
cenpcCENP-C_C domain-containing protein. (1378 aa)
pmf1LOC100037873 protein. (202 aa)
cenptProstaglandin D2 synthase. (777 aa)
spc24Kinetochore protein spc24; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. (205 aa)
cenpiUncharacterized protein. (718 aa)
CENPWCentromere protein W. (108 aa)
nuf2Msh homeobox 1. (462 aa)
cenpnCentromere protein N; Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation; Belongs to the CENP-N/CHL4 family. (366 aa)
cenplCentromere protein L; Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation; Belongs to the CENP-L/IML3 family. (348 aa)
CENPKCentromere protein K. (291 aa)
spc25Kinetochore protein Spc25; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. (228 aa)
knl1Uncharacterized loc496670. (2794 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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