STRINGSTRING
HAPLN2 HAPLN2 PDGFC PDGFC edn1 edn1 slc39a1 slc39a1 WNT1 WNT1 bmp2 bmp2 rarg rarg LOC105946502 LOC105946502 bmp6 bmp6 arsd arsd alcam alcam mrps15-2 mrps15-2 wdr19 wdr19 vhl-3 vhl-3 ucma ucma tsku tsku rflnb rflnb HOXC11 HOXC11 rara rara hoxc6 hoxc6 hoxc5 hoxc5 evc evc HOXC4 HOXC4 ep300 ep300 sox1 sox1 CYTL1 CYTL1 msx1 msx1 ppib ppib SHOX SHOX sox5 sox5 med1l med1l wdr19-2 wdr19-2 nkx3-2 nkx3-2 GLG1 GLG1 ANKRD11 ANKRD11 LOC101730485 LOC101730485 RUNX3 RUNX3 rai1 rai1 OTOR OTOR smad2 smad2 MATN3 MATN3 irx5 irx5 smad3 smad3 crtac1 crtac1 K9J7P7_XENTR K9J7P7_XENTR snx19 snx19 ccn1 ccn1 DDR2 DDR2 dlx2 dlx2 ANXA6 ANXA6 bmp7.2 bmp7.2 mmp9.1 mmp9.1 SERPINH1 SERPINH1 wnt9b.2 wnt9b.2 trim45 trim45 WNT9A WNT9A arsh arsh dhrs3 dhrs3 shox2 shox2 tcf15 tcf15 zfand5 zfand5 miga2 miga2 MYOC MYOC sh2b3 sh2b3 s1pr2 s1pr2 runx1 runx1 wnt11 wnt11 NIPBL NIPBL ppargc1b ppargc1b p2rx7 p2rx7 LOC100490828 LOC100490828 wfikkn1 wfikkn1 PAX1 PAX1 chrd.1 chrd.1 ryk ryk polr2f-2 polr2f-2 pkd1 pkd1 NSD2 NSD2 snai2 snai2 mef2d mef2d BCAN BCAN LOC101730428 LOC101730428 psen1 psen1 fmr1 fmr1 JAG2 JAG2 TNFSF11 TNFSF11 ddr2l ddr2l bmp4 bmp4 CREB3L2 CREB3L2 tgfbr2 tgfbr2 ecm1 ecm1 phospho2 phospho2 slc38a10 slc38a10 runx2 runx2 srf srf ENSXETP00000018188 ENSXETP00000018188 ptpn6 ptpn6 BMPR1A BMPR1A sfrp2 sfrp2 LRRK1 LRRK1 lrp5 lrp5 mkks mkks chst11 chst11 LOC100494742 LOC100494742 bmp7.1 bmp7.1 sp5 sp5 bnc2 bnc2 ENSXETP00000020321 ENSXETP00000020321 fgf8 fgf8 wnt11-2 wnt11-2 sulf1 sulf1 tgfb1 tgfb1 ift140 ift140 TMEM119 TMEM119 pkdcc.2 pkdcc.2 wnt7b wnt7b zbtb16 zbtb16 bbx bbx csrnp1 csrnp1 dlx5 dlx5 rab23 rab23 cblb cblb rspo2 rspo2 snx10 snx10 hoxa1 hoxa1 hoxa2 hoxa2 hoxa3 hoxa3 hoxa5 hoxa5 hoxa6 hoxa6 scamp5.2 scamp5.2 hoxa11 hoxa11 sox6 sox6 hoxc10 hoxc10 hoxc9 hoxc9 hoxc8 hoxc8 npr3 npr3 bglap bglap atg9a atg9a gli3 gli3 sox9 sox9 bbs1 bbs1 ebna1bp2-4 ebna1bp2-4 atp6ap1.2 atp6ap1.2 bmp5 bmp5 wasf2 wasf2 NCAN NCAN notum notum setd2 setd2 frem1 frem1 osr2 osr2 aldh1l1 aldh1l1 zmpste24 zmpste24 zhx2 zhx2 TAPT1 TAPT1 nog nog rars1 rars1 ccn3 ccn3 atg9b atg9b mks1 mks1 kit kit mmp14 mmp14 SGPL1 SGPL1 adamts12 adamts12 usp1 usp1 pbxip1 pbxip1 pdgfra pdgfra lep lep thbs3 thbs3 INPPL1 INPPL1 foxc1 foxc1 HAPLN1 HAPLN1 VCAN VCAN twsg1 twsg1 hnrnpc-2 hnrnpc-2 sp3 sp3 hoxc9-2 hoxc9-2 fuz fuz fgf4 fgf4 ext1 ext1 LOC100145507 LOC100145507 ENSXETP00000034825 ENSXETP00000034825 wdr60 wdr60 ADAMTS7 ADAMTS7 wwox wwox ift80 ift80 hmga2 hmga2 DDRGK1 DDRGK1 LOC100494987 LOC100494987 LOC101732240 LOC101732240 TRPS1 TRPS1 ext2 ext2 RANBP3L RANBP3L fst fst rab33b rab33b nab2 nab2 rb1 rb1 mapk14 mapk14 eif2ak3 eif2ak3 sema4d sema4d fgf6 fgf6 hand2 hand2 TTC9 TTC9 tgfbr1 tgfbr1 LOC100488097 LOC100488097 snai1 snai1 nog2 nog2 sh3pxd2b sh3pxd2b bmpr1b bmpr1b pkdcc.1 pkdcc.1 hexb hexb six2 six2 GP1BB GP1BB myf5 myf5 zeb1 zeb1 foxd3 foxd3 atp1b1-2 atp1b1-2 mab21l2 mab21l2 tp53 tp53 chad chad sulf2 sulf2 amer1 amer1 LOC100493338 LOC100493338 FAM20C FAM20C vps33b vps33b smc2-2 smc2-2 SIX4 SIX4 six1 six1 mcph1 mcph1 hspb11 hspb11 ctnnb1 ctnnb1 TP63 TP63 LOC100495918 LOC100495918 nppc nppc ednra ednra FREM1 FREM1 ENSXETP00000044071 ENSXETP00000044071 LOC100490019 LOC100490019 smad1 smad1 hhip hhip wnt9b wnt9b TMEM107 TMEM107 ctc1 ctc1 fli1 fli1 uncx uncx BARX2 BARX2 DEAF1 DEAF1 WFIKKN2 WFIKKN2 zfpm1 zfpm1 ITGB8 ITGB8 b3galnt2 b3galnt2 epyc epyc gsc gsc lepr lepr abi1 abi1 hand1 hand1 PHEX PHEX mbtps2 mbtps2 gas1 gas1 stc1 stc1 wnt5a wnt5a PHOSPHO1 PHOSPHO1 RARB RARB KIAA1217 KIAA1217 pex7 pex7 wnt5b wnt5b bmi1 bmi1 pcgf2 pcgf2 hoxb1 hoxb1 hoxb2 hoxb2 hoxb3 hoxb3 hoxb4 hoxb4 hoxb5 hoxb5 HOXB6 HOXB6 HOXB7 HOXB7 hoxb8 hoxb8 hoxb9 hoxb9 HOXD13 HOXD13 hoxd10 hoxd10 HOXD10 HOXD10 HOXD9 HOXD9 hoxd8 hoxd8 HOXD4 HOXD4 hoxd3 hoxd3 kremen1-2 kremen1-2 arhgap35-2 arhgap35-2 AKAP13 AKAP13 lrrc17 lrrc17 bbs2 bbs2 BMPR2 BMPR2 LOC100487454 LOC100487454 col2a1 col2a1 VDR VDR itgb6 itgb6 nle1 nle1 HYAL1 HYAL1 dmrt2 dmrt2 fbn1 fbn1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HAPLN2Hyaluronan and proteoglycan link protein 2. (331 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (347 aa)
edn1Nidogen 2. (222 aa)
slc39a1Solute carrier family 39 (Zinc transporter), member 1. (309 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
bmp2Armadillo like helical domain containing 3. (398 aa)
rargNucleoporin like 2. (476 aa)
LOC105946502Tectonic family member 2. (499 aa)
bmp6Enhancer of mRNA decapping 4. (441 aa)
arsdDEP domain-containing MTOR-interacting protein. (594 aa)
alcamUncharacterized protein. (573 aa)
mrps15-2Mitochondrial ribosomal protein S15. (233 aa)
wdr19Uncharacterized protein. (837 aa)
vhl-3Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (261 aa)
ucmaUnique cartilage matrix-associated protein C-terminal fragment; May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. Belongs to the UCMA family. (138 aa)
tskuTsukushin; Dorsalizing factor. Functions as an inhibitor of bone morphogenetic proteins (BMP) during gastrulation (By similarity). (350 aa)
rflnbBR serine/threonine kinase 2. (207 aa)
HOXC11Homeobox C11. (309 aa)
raraUncharacterized protein. (564 aa)
hoxc6Zinc finger DHHC-type containing 15. (234 aa)
hoxc5Homeobox domain-containing protein. (224 aa)
evcPatched domain containing 3. (931 aa)
HOXC4Homeobox C4. (297 aa)
ep300Suv3 like RNA helicase. (2493 aa)
sox13-phosphoinositide dependent protein kinase 1. (663 aa)
CYTL1Cytokine like 1. (182 aa)
msx1Potassium channel, two pore domain subfamily K, member 18. (275 aa)
ppibAntizyme inhibitor 1. (301 aa)
SHOXShort stature homeobox. (334 aa)
sox5Transcription factor Sox-5; Binds specifically to the DNA sequence 5'-AACAAT-3'. (694 aa)
med1lMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (678 aa)
wdr19-2Cyclin-dependent kinase 8. (1298 aa)
nkx3-2Homeobox domain-containing protein. (329 aa)
GLG1Golgi glycoprotein 1. (1148 aa)
ANKRD11Ankyrin repeat domain 11. (2761 aa)
LOC101730485Optineurin. (156 aa)
RUNX3Runt-related transcription factor. (396 aa)
rai1Latent transforming growth factor beta binding protein 3. (1847 aa)
OTOROtoraplin. (132 aa)
smad2Mothers against decapentaplegic homolog. (467 aa)
MATN3Matrilin 3. (378 aa)
irx5Iroquois-class homeodomain protein irx-5; Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes. Does not appear to play a role in pronephros kidney development. Involved in craniofacial and gonadal development (By similarity). Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12. (486 aa)
smad3Mothers against decapentaplegic homolog. (461 aa)
crtac1Cartilage acidic protein 1. (658 aa)
K9J7P7_XENTRUncharacterized protein. (167 aa)
snx19GTP-binding protein 10. (899 aa)
ccn1Histone deacetylase 2. (376 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (856 aa)
dlx2Distal-less homeobox 2. (285 aa)
ANXA6Annexin. (671 aa)
bmp7.2Nuclear receptor subfamily 5 group A member 1. (436 aa)
mmp9.1Uncharacterized protein. (692 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (450 aa)
wnt9b.2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (337 aa)
trim45Uncharacterized protein. (547 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (290 aa)
arshSulfatase domain-containing protein. (569 aa)
dhrs3Dehydrogenase/reductase (SDR family) member 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
shox2Cartilage acidic protein 1. (311 aa)
tcf15BHLH domain-containing protein. (161 aa)
zfand5High mobility group protein 20A. (211 aa)
miga2Kidney mitochondrial carrier protein 1. (589 aa)
MYOCMyocilin. (499 aa)
sh2b3Uncharacterized protein. (617 aa)
s1pr2tRNA selenocysteine 1 associated protein 1. (349 aa)
runx1Runt-related transcription factor. (522 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
NIPBLNipped-B protein. (2938 aa)
ppargc1bAcylphosphatase-1. (937 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (558 aa)
LOC100490828P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (559 aa)
wfikkn1Carbohydrate (keratan sulfate Gal-6) sulfotransferase 1. (545 aa)
PAX1Paired box 1. (357 aa)
chrd.1Chordin; Belongs to the chordin family. (942 aa)
rykUncharacterized protein. (601 aa)
polr2f-2Matrix Gla protein; Associates with the organic matrix of bone and cartilage. (115 aa)
pkd1L-threonine dehydrogenase (pseudogene). (4091 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1308 aa)
snai2Snail homolog 2 (Drosophila). (266 aa)
mef2dMADS-box domain-containing protein. (496 aa)
BCANBrevican. (1148 aa)
LOC101730428Uncharacterized protein. (970 aa)
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
fmr1Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C). ECO:0000250|UniProtKB:P51113, ECO:0000250|UniProtKB:Q06787. (590 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1133 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (290 aa)
ddr2lDiscoidin domain receptor family, member 2. (879 aa)
bmp4Zinc finger, HIT-type-containing 6. (469 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (525 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (728 aa)
ecm1O-phosphoseryl-tRNA(Sec) selenium transferase. (455 aa)
phospho2Probable phosphatase phospho2; Probable phosphatase; Belongs to the HAD-like hydrolase superfamily. PHOSPHO family. (238 aa)
slc38a10Rho GTPase activating protein 1. (1066 aa)
runx2Runt-related transcription factor. (468 aa)
srfHydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7. (359 aa)
ENSXETP00000018188SH2 domain-containing protein. (66 aa)
ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (601 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
LRRK1Leucine rich repeat kinase 1. (2003 aa)
lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
mkksNeuronal calcium sensor 1. (611 aa)
chst11Carbohydrate sulfotransferase. (352 aa)
LOC100494742DNA polymerase mu. (518 aa)
bmp7.1TGF_BETA_2 domain-containing protein. (425 aa)
sp5Uncharacterized protein. (374 aa)
bnc2Cell division cycle 27. (1052 aa)
ENSXETP00000020321S-adenosylmethionine sensor upstream of mTORC1. (158 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
wnt11-2Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Shares much functionality with wnt11b. Signals through a non-canonical Wnt pathway to activate Jun-N- terminal kinase (JNK) to regulate gastrulation movements. Acts in a non-cell-autonomous manner to control neural crest migration, probably acting as an extracellular signal from surrounding tissue, but is not required for neural crest induction. Acts redundantly with wnt11b during pronephros induction. Regulates cardiac morphogenesis through the activation of JNK, but is not requ [...] (352 aa)
sulf1Uncharacterized protein. (1145 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
ift140Uncharacterized protein. (1461 aa)
TMEM119Transmembrane protein 119. (287 aa)
pkdcc.2PIP49_C domain-containing protein. (241 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (285 aa)
zbtb16Collagen, type IX, alpha 3. (660 aa)
bbxPhosphoribosyltransferase domain-containing protein 1. (899 aa)
csrnp1AXIN1 up-regulated 1. (574 aa)
dlx5Nuclear factor of activated T cells 3. (298 aa)
rab23RAB23, member RAS oncogene family. (238 aa)
cblbE3 ubiquitin-protein ligase CBL-B; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. (982 aa)
rspo2R-spondin-2; Activator of the canonical Wnt signaling pathway by acting as a ligand for lgr4-6 receptors. Upon binding to lgr4-6 (lgr4, lgr5 or lgr6), lgr4-6 associate with phosphorylated lrp6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Acts both in the canonical. Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway (By similarity). Activates neural markers and promotes muscle formation. Overexpression blocks activin, nodal and BMP4 signaling, su [...] (243 aa)
snx10Seryl-tRNA synthetase 2, mitochondrial. (171 aa)
hoxa1Homeobox A1. (323 aa)
hoxa2Homeobox domain-containing protein. (373 aa)
hoxa3Pre-B-cell leukemia transcription factor 2. (406 aa)
hoxa5Proteasome subunit beta 7. (274 aa)
hoxa6Aldehyde dehydrogenase 7 family member A1. (237 aa)
scamp5.2Homeobox domain-containing protein. (90 aa)
hoxa11Lamin B1. (299 aa)
sox6Transcription factor Sox-6; Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation (By similarity). (804 aa)
hoxc10Toll-interacting protein. (351 aa)
hoxc9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (269 aa)
hoxc8Homeo box C8. (242 aa)
npr3Chromosome 20 open reading frame 194. (508 aa)
bglapOsteocalcin; Binds strongly to apatite and calcium. (101 aa)
atg9aAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (1099 aa)
gli3Centrosomal protein 164kDa. (1566 aa)
sox9Transcription factor Sox-9; Transcription activator. Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox8 and sox10 to induce neural crest progenitors. Induces sox10 expression downstream of wnt-signaling. Principally involved in development of the cranial neural crest, which is fated to form skeletal elements. Also required for otic placode specification during inner ear development (By similarity). May be involved in chondrogenesis (cartilage development) during bone formation. Unlikely to play a role in sex determination but may funct [...] (482 aa)
bbs1Coiled-coil domain containing 84. (591 aa)
ebna1bp2-4EBNA1 binding protein 2. (876 aa)
atp6ap1.2Uncharacterized protein. (462 aa)
bmp5Apoptosis antagonizing transcription factor. (449 aa)
wasf2Forkhead box Q1. (484 aa)
NCANNeurocan. (628 aa)
notumUncharacterized protein. (491 aa)
setd2H2A histone family member Y. (2971 aa)
frem1Cyclin G1. (2023 aa)
osr2Podocan. (312 aa)
aldh1l1Cytosolic 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (951 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (472 aa)
zhx2TBC1 domain family member 31. (1872 aa)
TAPT1Transmembrane anterior posterior transformation 1. (549 aa)
nogNoggin; Belongs to the noggin family. (222 aa)
rars1Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. (688 aa)
ccn3Superoxide dismutase [Cu-Zn]. (344 aa)
atg9bAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (768 aa)
mks1Heterogeneous nuclear ribonucleoprotein R. (555 aa)
kitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (966 aa)
mmp14ZnMc domain-containing protein. (622 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (573 aa)
adamts12ADAM metallopeptidase domain 10. (1540 aa)
usp1Ubiquitin carboxyl-terminal hydrolase. (774 aa)
pbxip1Protein interacting with PRKCA 1. (754 aa)
pdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1096 aa)
lepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
thbs3Uncharacterized protein. (850 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (925 aa)
foxc1Forkhead box protein C1; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Required for cell viability and resistance to oxidative stress in the eye. Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1- mediated signals. Involved in epi [...] (495 aa)
HAPLN1Hyaluronan and proteoglycan link protein 1. (350 aa)
VCANVersican. (3727 aa)
twsg1Uncharacterized protein. (339 aa)
hnrnpc-2Heterogeneous nuclear ribonucleoprotein C (C1/C2). (181 aa)
sp3Zona pellucida glycoprotein 3 (sperm receptor), gene 2. (731 aa)
hoxc9-2Synapsin II. (81 aa)
fuzProtein fuzzy homolog; Probable planar cell polarity effector involved in cilium biogenesis. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies. May regulate protein and membrane transport to the cilium. May control the organization of the apical actin cytoskeleton, which is essential for the normal orientation of elongating ciliary microtubules. (418 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
ext1G protein-coupled receptor 75; Belongs to the glycosyltransferase 47 family. (738 aa)
LOC100145507LOC100145507 protein. (684 aa)
ENSXETP00000034825Uncharacterized protein. (666 aa)
wdr60WD repeat domain 60. (1116 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1561 aa)
wwoxRUNX family transcription factor 1. (381 aa)
ift80Intraflagellar transport 80 homolog. (779 aa)
hmga2Rho guanine nucleotide exchange factor 38. (150 aa)
DDRGK1DDRGK domain containing 1. (240 aa)
LOC100494987Uncharacterized protein. (485 aa)
LOC101732240Poly [ADP-ribose] polymerase. (492 aa)
TRPS1Transcriptional repressor GATA binding 1. (1273 aa)
ext2Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (723 aa)
RANBP3LRAN binding protein 3 like. (520 aa)
fstChloride channel, voltage-sensitive 6. (343 aa)
rab33bRAB33B, member RAS oncogene family. (226 aa)
nab2Chromodomain helicase DNA binding protein 3. (505 aa)
rb1Uncharacterized protein. (914 aa)
mapk14Mitogen-activated protein kinase. (361 aa)
eif2ak3Carnitine palmitoyltransferase 1A (liver) like. (929 aa)
sema4dKeratin 70; Belongs to the semaphorin family. (862 aa)
fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
hand2Hand2 protein. (210 aa)
TTC9Tetratricopeptide repeat domain 9. (327 aa)
tgfbr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
LOC100488097Fibronectin type-III domain-containing protein. (660 aa)
snai1Uncharacterized protein. (336 aa)
nog2Noggin; Belongs to the noggin family. (218 aa)
sh3pxd2bADP-ribosyltransferase 1. (952 aa)
bmpr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
pkdcc.1Heterogeneous nuclear ribonucleoprotein L. (457 aa)
hexbBeta-hexosaminidase. (555 aa)
six2Homeobox domain-containing protein. (287 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (206 aa)
myf5Myogenic factor. (255 aa)
zeb1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (1121 aa)
foxd3Forkhead box protein D3; Transcriptional repressor that is an essential upstream regulator of neural crest determination. Also acts in a negative auto- regulator loop by inhibiting the transcription of its own gene (By similarity). (369 aa)
atp1b1-2ATPase Na+/K+ transporting subunit beta 1. (124 aa)
mab21l2Protein mab-21-like 2; Required for several aspects of embryonic development including normal development of the eye. Belongs to the mab-21 family. (359 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa)
chadUncharacterized protein. (360 aa)
sulf2Extracellular sulfatase. (875 aa)
amer1Endoplasmic reticulum to nucleus signaling 2. (1081 aa)
LOC100493338Adrenoceptor alpha 1D. (206 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (575 aa)
vps33bUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (612 aa)
smc2-2Structural maintenance of chromosomes 2. (1957 aa)
SIX4SIX homeobox 4. (817 aa)
six1Six1 protein. (284 aa)
mcph1Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa. (820 aa)
hspb11Novel protein similar to c1orf41. (139 aa)
ctnnb1Dynactin subunit 5. (788 aa)
TP63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (662 aa)
LOC100495918Tolloid like 1. (130 aa)
nppcUncharacterized protein. (128 aa)
ednraEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (414 aa)
FREM1FRAS1 related extracellular matrix 1. (2042 aa)
ENSXETP00000044071Peptidase_M10 domain-containing protein. (159 aa)
LOC100490019Zinc finger MIZ-type containing 2. (472 aa)
smad1Mothers against decapentaplegic homolog. (464 aa)
hhipSecurin-like. (678 aa)
wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
TMEM107Transmembrane protein 107. (140 aa)
ctc1Mitogen-activated protein kinase 1. (1047 aa)
fli1Fli1 protein. (459 aa)
uncxUNC homeobox transcription factor. (483 aa)
BARX2BARX homeobox 2. (288 aa)
DEAF1DEAF1 transcription factor. (478 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (559 aa)
zfpm1C-terminal Src kinase. (1214 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (726 aa)
b3galnt2UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2; Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O- glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (dag1) glycosylation (By similarity); Belongs to the glycosyltransferase 31 family. (534 aa)
epycDermatan sulfate proteoglycan 3. (318 aa)
gscHomeobox domain-containing protein. (275 aa)
leprLeucine-rich repeat-containing protein 42. (1138 aa)
abi1Uncharacterized protein. (502 aa)
hand1Glycogen synthase kinase 3 beta. (213 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (733 aa)
mbtps2Peptidase_M50 domain-containing protein. (494 aa)
gas1Uncharacterized protein. (289 aa)
stc1Serine/threonine kinase 16. (247 aa)
wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (402 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (245 aa)
RARBRetinoic acid receptor beta. (474 aa)
KIAA1217KIAA1217. (1748 aa)
pex7Ring finger protein 157. (354 aa)
wnt5bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
bmi1Quinolinate phosphoribosyltransferase. (325 aa)
pcgf2Vesicle (multivesicular body) trafficking 1. (317 aa)
hoxb1Dehydrogenase/reductase (SDR family) member 7. (304 aa)
hoxb2Mevalonate kinase. (340 aa)
hoxb3Homeo box B3. (386 aa)
hoxb4Protein phosphatase, Mg2+/Mn2+ dependent 1J. (261 aa)
hoxb5Hoxb5 protein. (258 aa)
HOXB6Homeobox B6. (223 aa)
HOXB7Homeobox B7. (216 aa)
hoxb8Regulating synaptic membrane exocytosis 3. (243 aa)
hoxb9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (246 aa)
HOXD13Homeobox D13. (300 aa)
hoxd10Insulin receptor substrate 1. (274 aa)
HOXD10Homeobox D10. (338 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (278 aa)
hoxd8Homeobox domain-containing protein. (231 aa)
HOXD4Homeobox D4. (237 aa)
hoxd3Cytosolic arginine sensor for mTORC1 subunit 2. (415 aa)
kremen1-2Kringle containing transmembrane protein 1. (289 aa)
arhgap35-2Rho GTPase activating protein 35. (688 aa)
AKAP13A-kinase anchoring protein 13. (1794 aa)
lrrc17Mitogen-activated protein kinase kinase kinase kinase 3. (428 aa)
bbs2Bardet-Biedl syndrome 2 protein homolog. (749 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
LOC100487454Uncharacterized protein. (454 aa)
col2a1Collagen alpha-1(II) chain; Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces (By similarity). (1492 aa)
VDRVitamin D receptor. (420 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (782 aa)
nle1WD_REPEATS_REGION domain-containing protein. (486 aa)
HYAL1Hyaluronidase. (753 aa)
dmrt2Lysine (K)-specific demethylase 2B. (528 aa)
fbn1Abl interactor 1. (2882 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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