STRINGSTRING
CENPF CENPF SMO SMO calb1 calb1 podxl podxl mecr mecr hey1 hey1 nle1 nle1 NOTCH3 NOTCH3 pax8 pax8 traf3ip1 traf3ip1 grem1 grem1 gdf5-2 gdf5-2 LAMB2 LAMB2 cyp7b1 cyp7b1 hoxd10 hoxd10 HOXD13 HOXD13 WNT6 WNT6 PTCH1 PTCH1 greb1l greb1l DLG5 DLG5 RARB RARB greb1 greb1 nkx3-1 nkx3-1 plce1 plce1 PLXND1 PLXND1 ITGA3 ITGA3 ube3a ube3a tnc tnc myocd myocd esr1 esr1 nup85 nup85 LOC105947166 LOC105947166 gata3 gata3 wdr77 wdr77 LOC105947355 LOC105947355 wnt9b wnt9b commd5 commd5 smad1 smad1 PCSK9 PCSK9 ednra ednra DYNC2H1 DYNC2H1 CEP290 CEP290 nphs2 nphs2 TP63 TP63 ctnnb1 ctnnb1 epcam epcam hspb11 hspb11 six1 six1 SIX4 SIX4 tfap2e tfap2e amer1 amer1 ptcd2 ptcd2 gcnt3 gcnt3 cnksr2-2 cnksr2-2 sulf2 sulf2 ndrg1 ndrg1 ednrb2 ednrb2 LAMB1 LAMB1 fras1 fras1 six2 six2 upk3a upk3a GCNT4 GCNT4 tp73 tp73 agt agt tgfbr1 tgfbr1 FREM3 FREM3 STRA6 STRA6 pkd2 pkd2 hs2st1 hs2st1 rtn4rl1-3 rtn4rl1-3 anks6 anks6 LOC101732240 LOC101732240 LOC100494987 LOC100494987 serpinf1 serpinf1 NUP133 NUP133 slit2 slit2 LOC100145507 LOC100145507 eaf2 eaf2 foxc1 foxc1 prkx prkx smad4.1 smad4.1 tshz1 tshz1 BCL2 BCL2 WDPCP WDPCP mpst mpst mtss1.1 mtss1.1 ift27 ift27 frs2-2 frs2-2 SGPL1 SGPL1 crlf1 crlf1 fem1b fem1b CNTRL CNTRL dll1 dll1 tsc1 tsc1 wt1 wt1 zmpste24 zmpste24 osr2 osr2 lrp4 lrp4 HNF1B HNF1B NPHS1 NPHS1 ap1b1 ap1b1 gcnt1 gcnt1 gli3 gli3 hells hells Smad6.2 Smad6.2 ar ar TTC8 TTC8 AHI1 AHI1 kif26b kif26b dlc dlc hoxa11 hoxa11 scamp5.2 scamp5.2 agtr1 agtr1 pecam1 pecam1 jmjd6 jmjd6 basp1 basp1 c1galt1 c1galt1 zbtb16 zbtb16 wfs1 wfs1 tfap2a tfap2a IFT88 IFT88 SOX8 SOX8 tgfb1 tgfb1 sulf1 sulf1 wnt11-2 wnt11-2 zfp36l2 zfp36l2 fgf8 fgf8 tns2 tns2 traf3ip3 traf3ip3 ZBTB14 ZBTB14 tfap2b tfap2b pdgfb-2 pdgfb-2 RET RET NF1 NF1 dchs2 dchs2 efnb2 efnb2 jag1 jag1 lrrk2 lrrk2 bag6 bag6 irx1 irx1 bmp4 bmp4 ace ace LOC100496837 LOC100496837 LOC100486174 LOC100486174 LOC100486323 LOC100486323 lrp2 lrp2 dnajc15 dnajc15 tcf21 tcf21 triap1 triap1 bmper bmper kank2 kank2 pkd1 pkd1 PYGO1 PYGO1 wnt11 wnt11 AMH AMH wnt4 wnt4 gdnf gdnf spry1 spry1 fgf2 fgf2 enpep enpep ilk ilk acvr1 acvr1 prdm1 prdm1 osr1 osr1 cpeb3 cpeb3 wnt9b.2 wnt9b.2 nphp3 nphp3 TBC1D32 TBC1D32 bax bax nup107 nup107 tmem59l tmem59l ednrb ednrb kctd1 kctd1 bcl2l11 bcl2l11 ap2b1 ap2b1 K9J7P7_XENTR K9J7P7_XENTR SMAD7 SMAD7 smad3 smad3 BICC1 BICC1 SMAD6 SMAD6 RPGRIP1L RPGRIP1L irx3 irx3 smad2 smad2 FREM2 FREM2 usp7-2 usp7-2 GLIS2 GLIS2 ptpro ptpro dchs1 dchs1 ARL3 ARL3 rara rara HOXC11 HOXC11 sox7 sox7 gzf1 gzf1 fgf1 fgf1 bmp6 bmp6 rarg rarg bmp2 bmp2 WNT1 WNT1 cirbp cirbp stk11 stk11 PKHD1 PKHD1 LOC100485879 LOC100485879 LOC100486030 LOC100486030
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CENPFCentromere protein F. (2609 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
calb1Stromal interaction molecule 1. (287 aa)
podxlGamma-aminobutyric acid (GABA) B receptor, 1. (459 aa)
mecrEnoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro (By similarity). Functions in pronephros development, regulating late differentiation of all pronephric tubule segments. (351 aa)
hey1Hairy/enhancer-of-split related with YRPW motif protein 1; Downstream effector of Notch signaling. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Acts as a suppressor of neurogenesis by antagonizing proneural gene function. Functions during floorplate development. Plays a role in pronephros formation in the inhibition of distal tubule and duct cell fates and the promotion of glomus and proximal tubule formation (By similarity). (300 aa)
nle1WD_REPEATS_REGION domain-containing protein. (486 aa)
NOTCH3Notch receptor 3. (2413 aa)
pax8Paired box protein Pax-8; Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 to establish the pronephric primordium in late gastrulae/early neurulae (By similarity). (466 aa)
traf3ip1Uncharacterized protein. (628 aa)
grem1Gremlin. (182 aa)
gdf5-2Growth differentiation factor 5. (1420 aa)
LAMB2Laminin subunit beta 2. (1793 aa)
cyp7b1V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K; Belongs to the cytochrome P450 family. (491 aa)
hoxd10Insulin receptor substrate 1. (274 aa)
HOXD13Homeobox D13. (300 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa)
PTCH1Patched 1. (1430 aa)
greb1lUncharacterized protein. (1970 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1971 aa)
RARBRetinoic acid receptor beta. (474 aa)
greb1Pecanex 4. (1898 aa)
nkx3-1Homeobox domain-containing protein. (211 aa)
plce1Phosphoinositide phospholipase C. (2207 aa)
PLXND1Plexin D1. (1867 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1046 aa)
ube3aUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (908 aa)
tncAdenylate cyclase activating polypeptide 1 (pituitary). (1983 aa)
myocdYip1 domain family member 1. (956 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
nup85Nuclear pore complex protein Nup85; Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Involved in nephrogenesis ; Belongs to the nucleoporin Nup85 family. (808 aa)
LOC105947166Glucosaminyl (N-acetyl) transferase 3, mucin type. (1428 aa)
gata3Uncharacterized protein. (454 aa)
wdr77Chromosome 11 open reading frame 68. (323 aa)
LOC105947355Uncharacterized protein. (1169 aa)
wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
commd5COMM domain-containing protein. (223 aa)
smad1Mothers against decapentaplegic homolog. (464 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (684 aa)
ednraEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (414 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4246 aa)
CEP290Centrosomal protein 290. (2365 aa)
nphs2Musashi RNA-binding protein 2. (376 aa)
TP63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (662 aa)
ctnnb1Dynactin subunit 5. (788 aa)
epcamEpithelial cell adhesion molecule. (312 aa)
hspb11Novel protein similar to c1orf41. (139 aa)
six1Six1 protein. (284 aa)
SIX4SIX homeobox 4. (817 aa)
tfap2eTF_AP-2 domain-containing protein. (434 aa)
amer1Endoplasmic reticulum to nucleus signaling 2. (1081 aa)
ptcd2Uncharacterized protein. (382 aa)
gcnt3Solute carrier family 24 member 4. (443 aa)
cnksr2-2Connector enhancer of kinase suppressor of Ras 2. (431 aa)
sulf2Extracellular sulfatase. (875 aa)
ndrg1Protein NDRG1; May be involved in pronephros development, after specification of the pronephros. (399 aa)
ednrb2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (435 aa)
LAMB1Laminin subunit beta 1. (1808 aa)
fras1KAT8 regulatory NSL complex subunit 1-like protein. (3983 aa)
six2Homeobox domain-containing protein. (287 aa)
upk3aEstablishment of sister chromatid cohesion N-acetyltransferase 2. (255 aa)
GCNT4Glucosaminyl (N-acetyl) transferase 4. (431 aa)
tp73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (632 aa)
agtSERPIN domain-containing protein; Belongs to the serpin family. (459 aa)
tgfbr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
FREM3FRAS1 related extracellular matrix 3. (3133 aa)
STRA6Stimulated by retinoic acid 6. (637 aa)
pkd2Ubiquitin carboxyl-terminal hydrolase 33. (951 aa)
hs2st1LOC100145562 protein. (356 aa)
rtn4rl1-3Reticulon 4 receptor-like 1. (414 aa)
anks6Uncharacterized protein. (903 aa)
LOC101732240Poly [ADP-ribose] polymerase. (492 aa)
LOC100494987Uncharacterized protein. (485 aa)
serpinf1Serine (Or cysteine) proteinase inhibitor, clade F, member 1; Belongs to the serpin family. (409 aa)
NUP133Nucleoporin 133. (1142 aa)
slit2ATPase family, AAA domain containing 3A. (1564 aa)
LOC100145507LOC100145507 protein. (684 aa)
eaf2Helicase with zinc finger. (297 aa)
foxc1Forkhead box protein C1; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Required for cell viability and resistance to oxidative stress in the eye. Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1- mediated signals. Involved in epi [...] (495 aa)
prkxUncharacterized protein; Belongs to the protein kinase superfamily. (369 aa)
smad4.1Mothers against decapentaplegic homolog. (579 aa)
tshz1Tetraspanin 2. (1095 aa)
BCL2BCL2 apoptosis regulator. (293 aa)
WDPCPWD repeat containing planar cell polarity effector. (708 aa)
mpstSulfurtransferase. (299 aa)
mtss1.1Gephyrin. (722 aa)
ift27Uncharacterized protein. (210 aa)
frs2-2Frs2 protein. (509 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (573 aa)
crlf1Mitochondrial E3 ubiquitin protein ligase 1. (387 aa)
fem1bDiscs, large homolog-associated protein 3. (681 aa)
CNTRLCentriolin. (2247 aa)
dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (740 aa)
tsc1Distal-less homeobox 1. (1139 aa)
wt1Wilms tumor protein homolog; Transcription factor required for development of the vascular component of the pronephric kidney, the glomus; may repress tubule- specific gene expression in the portion of the pronephros fated to form the glomus (By similarity). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (By similarity). Inhibits Wnt-signaling during embryonic development (By similarity); Belongs to the EGR C2H2-type zinc-finger protein family. (452 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (472 aa)
osr2Podocan. (312 aa)
lrp4Glycoprotein A33 (transmembrane). (1832 aa)
HNF1BHNF1 homeobox B. (566 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1078 aa)
ap1b1AP complex subunit beta. (946 aa)
gcnt1Coiled-coil domain containing 77. (426 aa)
gli3Centrosomal protein 164kDa. (1566 aa)
hellsUncharacterized protein. (840 aa)
Smad6.2MH2 domain-containing protein. (206 aa)
arTransforming acidic coiled-coil containing protein 3. (788 aa)
TTC8Tetratricopeptide repeat domain 8. (516 aa)
AHI1Abelson helper integration site 1. (747 aa)
kif26bGlycogenin 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2097 aa)
dlcDelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa)
hoxa11Lamin B1. (299 aa)
scamp5.2Homeobox domain-containing protein. (90 aa)
agtr1Agtr1.2 protein; Belongs to the G-protein coupled receptor 1 family. (355 aa)
pecam1Uncharacterized protein. (726 aa)
jmjd6JmjC domain-containing protein. (403 aa)
basp1Brain abundant, membrane attached signal protein 1. (238 aa)
c1galt1Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (354 aa)
zbtb16Collagen, type IX, alpha 3. (660 aa)
wfs1LOC100127642 protein. (863 aa)
tfap2aBeta-1,4-N-acetyl-galactosaminyl transferase 1. (451 aa)
IFT88Intraflagellar transport 88. (826 aa)
SOX8SRY-box transcription factor 8. (466 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
sulf1Uncharacterized protein. (1145 aa)
wnt11-2Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Shares much functionality with wnt11b. Signals through a non-canonical Wnt pathway to activate Jun-N- terminal kinase (JNK) to regulate gastrulation movements. Acts in a non-cell-autonomous manner to control neural crest migration, probably acting as an extracellular signal from surrounding tissue, but is not required for neural crest induction. Acts redundantly with wnt11b during pronephros induction. Regulates cardiac morphogenesis through the activation of JNK, but is not requ [...] (352 aa)
zfp36l2mRNA decay activator protein ZFP36L2; Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis (By similarity). Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery (By similarity). Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-con [...] (362 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
tns2Erythrocyte membrane protein band 4.1-like 1. (1239 aa)
traf3ip3TRAF3 interacting protein 2. (333 aa)
ZBTB14Zinc finger and BTB domain containing 14. (452 aa)
tfap2bMethionine adenosyltransferase II, alpha. (464 aa)
pdgfb-2Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1101 aa)
NF1Neurofibromin 1. (2812 aa)
dchs2Uncharacterized protein. (3254 aa)
efnb2Solute carrier family 41 member 2; Belongs to the ephrin family. (329 aa)
jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
lrrk2Hes family bHLH transcription factor 2. (2514 aa)
bag6Large proline-rich protein bag6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the bag6/bat3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endo [...] (1135 aa)
irx1Iroquois-class homeodomain protein irx-1; Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Acts early in neural plate development to induce expression of some but not all proneural genes, and specify a neural precursor state. Also up- regulates repressors that prevent neuronal differentiation. Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes. Acts primarily as a transcriptional repressor during neural development, and binds [...] (467 aa)
bmp4Zinc finger, HIT-type-containing 6. (469 aa)
aceAngiotensin-converting enzyme. (1337 aa)
LOC100496837GDNF family receptor alpha 2. (348 aa)
LOC100486174Solute carrier family 13 member 4 like. (334 aa)
LOC100486323Transmembrane protein 143. (321 aa)
lrp2Rab geranylgeranyltransferase subunit beta. (4662 aa)
dnajc15DnaJ homolog subfamily C member 15; Negative regulator of the mitochondrial respiratory chain (By similarity). Plays a role in the translocation of proteins across the mitochondrial inner membrane (By similarity). Involved in pronephric kidney development at the early tadpole stage. (187 aa)
tcf21Transcription factor 21; Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. (179 aa)
triap1TP53-regulated inhibitor of apoptosis 1; Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. The triap1:prelid1 complex probably functions as a phosphatidic acid (PA) transporter across the mitochondrion intermembrane space to provide PA for cardiolipin CL synthesis in the inner membrane. Likewise, the triap1:prelid3a complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo [...] (78 aa)
bmperUncharacterized protein. (741 aa)
kank2CLIP-associating protein 1. (887 aa)
pkd1L-threonine dehydrogenase (pseudogene). (4091 aa)
PYGO1Pygopus family PHD finger 1. (506 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
AMHAnti-Mullerian hormone. (606 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (227 aa)
spry1Mitochondrial amidoxime reducing component 1. (342 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
enpepAminopeptidase. (961 aa)
ilkUncharacterized protein. (286 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (568 aa)
prdm1ChaC, cation transport regulator homolog 2. (784 aa)
osr1Protein odd-skipped-related 1; Transcriptional repressor (By similarity). Required for pronephric kidney development. (215 aa)
cpeb3Cytoplasmic polyadenylation element-binding protein 3; Sequence-specific RNA-binding protein which acts as a translational repressor in the basal unstimulated state but, following neuronal stimulation, acts as a translational activator (By similarity). Does not bind to the cytoplasmic polyadenylation element (CPE), a uridine-rich sequence element within the mRNA 3'-UTR, but binds to a U-rich loop within a stem-loop structure (By similarity). Required for the consolidation and maintenance of hippocampal-based long term memory (By similarity). Inhibits differentiation of intermediate mes [...] (603 aa)
wnt9b.2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (337 aa)
nphp3Nephrocystin-3; Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling that regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements (By similarity). (1266 aa)
TBC1D32TBC1 domain family member 32. (1300 aa)
baxBCL2-associated X protein. (221 aa)
nup107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (916 aa)
tmem59lLOC100158571 protein. (335 aa)
ednrbAconitase 2; Belongs to the G-protein coupled receptor 1 family. (433 aa)
kctd1Potassium channel tetramerization domain containing 1. (302 aa)
bcl2l11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (194 aa)
ap2b1AP complex subunit beta. (970 aa)
K9J7P7_XENTRUncharacterized protein. (167 aa)
SMAD7Mothers against decapentaplegic homolog. (382 aa)
smad3Mothers against decapentaplegic homolog. (461 aa)
BICC1BicC family RNA binding protein 1. (918 aa)
SMAD6Mothers against decapentaplegic homolog. (352 aa)
RPGRIP1LRPGRIP1 like. (1266 aa)
irx3Iroquois-class homeodomain protein irx-3; Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Both up- regulates and down-regulates gene expression during neural development. Acts early in neural plate development to induce proneural gene expression and specify a neural precursor state. Also up-regulates repressors that prevent neuronal differentiation. Required during at least two stages of pronephros kidney development; during neurula stages, maintains tran [...] (448 aa)
smad2Mothers against decapentaplegic homolog. (467 aa)
FREM2FRAS1 related extracellular matrix 2. (3126 aa)
usp7-2Ubiquitin specific peptidase 7 (herpes virus-associated). (316 aa)
GLIS2GLIS family zinc finger 2. (493 aa)
ptproORMDL sphingolipid biosynthesis regulator 1. (1018 aa)
dchs1Uncharacterized protein. (2586 aa)
ARL3ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (195 aa)
raraUncharacterized protein. (564 aa)
HOXC11Homeobox C11. (309 aa)
sox7Transcription factor Sox-7; Transcription factor. Binds to the DNA sequence 5'-AACAAT-3'. Acts downstream of vegt and upstream of nodal signaling to promote endodermal and mesodermal differentiation by promoting vegt-induced expression of both endodermal genes (including endodermin) and mesodermal genes (including snai1/snail and snai2/slug). Induces expression of multiple nodal genes (including nodal, nodal2, nodal4, nodal5 and nodal6) and binds directly to sites within the promoter of the nodal5 gene. The endodermal and mesodermal specification pathways then interact to initiate card [...] (362 aa)
gzf1GDNF-inducible zinc finger protein 1. (697 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
bmp6Enhancer of mRNA decapping 4. (441 aa)
rargNucleoporin like 2. (476 aa)
bmp2Armadillo like helical domain containing 3. (398 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
cirbpCold-inducible RNA-binding protein; Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to themm and inhibiting their deadenylation. Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules, and cell movement during embryogenesis. Required for pronephros development (By similarity). (198 aa)
stk11Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (442 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (3166 aa)
LOC100485879Taste 1 receptor member 1. (357 aa)
LOC100486030Uncharacterized protein. (311 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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