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CENPF | Centromere protein F. (2609 aa) | ||||
SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa) | ||||
calb1 | Stromal interaction molecule 1. (287 aa) | ||||
podxl | Gamma-aminobutyric acid (GABA) B receptor, 1. (459 aa) | ||||
mecr | Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro (By similarity). Functions in pronephros development, regulating late differentiation of all pronephric tubule segments. (351 aa) | ||||
hey1 | Hairy/enhancer-of-split related with YRPW motif protein 1; Downstream effector of Notch signaling. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Acts as a suppressor of neurogenesis by antagonizing proneural gene function. Functions during floorplate development. Plays a role in pronephros formation in the inhibition of distal tubule and duct cell fates and the promotion of glomus and proximal tubule formation (By similarity). (300 aa) | ||||
nle1 | WD_REPEATS_REGION domain-containing protein. (486 aa) | ||||
NOTCH3 | Notch receptor 3. (2413 aa) | ||||
pax8 | Paired box protein Pax-8; Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 to establish the pronephric primordium in late gastrulae/early neurulae (By similarity). (466 aa) | ||||
traf3ip1 | Uncharacterized protein. (628 aa) | ||||
grem1 | Gremlin. (182 aa) | ||||
gdf5-2 | Growth differentiation factor 5. (1420 aa) | ||||
LAMB2 | Laminin subunit beta 2. (1793 aa) | ||||
cyp7b1 | V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K; Belongs to the cytochrome P450 family. (491 aa) | ||||
hoxd10 | Insulin receptor substrate 1. (274 aa) | ||||
HOXD13 | Homeobox D13. (300 aa) | ||||
WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa) | ||||
PTCH1 | Patched 1. (1430 aa) | ||||
greb1l | Uncharacterized protein. (1970 aa) | ||||
DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1971 aa) | ||||
RARB | Retinoic acid receptor beta. (474 aa) | ||||
greb1 | Pecanex 4. (1898 aa) | ||||
nkx3-1 | Homeobox domain-containing protein. (211 aa) | ||||
plce1 | Phosphoinositide phospholipase C. (2207 aa) | ||||
PLXND1 | Plexin D1. (1867 aa) | ||||
ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1046 aa) | ||||
ube3a | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (908 aa) | ||||
tnc | Adenylate cyclase activating polypeptide 1 (pituitary). (1983 aa) | ||||
myocd | Yip1 domain family member 1. (956 aa) | ||||
esr1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa) | ||||
nup85 | Nuclear pore complex protein Nup85; Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Involved in nephrogenesis ; Belongs to the nucleoporin Nup85 family. (808 aa) | ||||
LOC105947166 | Glucosaminyl (N-acetyl) transferase 3, mucin type. (1428 aa) | ||||
gata3 | Uncharacterized protein. (454 aa) | ||||
wdr77 | Chromosome 11 open reading frame 68. (323 aa) | ||||
LOC105947355 | Uncharacterized protein. (1169 aa) | ||||
wnt9b | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa) | ||||
commd5 | COMM domain-containing protein. (223 aa) | ||||
smad1 | Mothers against decapentaplegic homolog. (464 aa) | ||||
PCSK9 | Proprotein convertase subtilisin/kexin type 9. (684 aa) | ||||
ednra | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (414 aa) | ||||
DYNC2H1 | Dynein cytoplasmic 2 heavy chain 1. (4246 aa) | ||||
CEP290 | Centrosomal protein 290. (2365 aa) | ||||
nphs2 | Musashi RNA-binding protein 2. (376 aa) | ||||
TP63 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (662 aa) | ||||
ctnnb1 | Dynactin subunit 5. (788 aa) | ||||
epcam | Epithelial cell adhesion molecule. (312 aa) | ||||
hspb11 | Novel protein similar to c1orf41. (139 aa) | ||||
six1 | Six1 protein. (284 aa) | ||||
SIX4 | SIX homeobox 4. (817 aa) | ||||
tfap2e | TF_AP-2 domain-containing protein. (434 aa) | ||||
amer1 | Endoplasmic reticulum to nucleus signaling 2. (1081 aa) | ||||
ptcd2 | Uncharacterized protein. (382 aa) | ||||
gcnt3 | Solute carrier family 24 member 4. (443 aa) | ||||
cnksr2-2 | Connector enhancer of kinase suppressor of Ras 2. (431 aa) | ||||
sulf2 | Extracellular sulfatase. (875 aa) | ||||
ndrg1 | Protein NDRG1; May be involved in pronephros development, after specification of the pronephros. (399 aa) | ||||
ednrb2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (435 aa) | ||||
LAMB1 | Laminin subunit beta 1. (1808 aa) | ||||
fras1 | KAT8 regulatory NSL complex subunit 1-like protein. (3983 aa) | ||||
six2 | Homeobox domain-containing protein. (287 aa) | ||||
upk3a | Establishment of sister chromatid cohesion N-acetyltransferase 2. (255 aa) | ||||
GCNT4 | Glucosaminyl (N-acetyl) transferase 4. (431 aa) | ||||
tp73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (632 aa) | ||||
agt | SERPIN domain-containing protein; Belongs to the serpin family. (459 aa) | ||||
tgfbr1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa) | ||||
FREM3 | FRAS1 related extracellular matrix 3. (3133 aa) | ||||
STRA6 | Stimulated by retinoic acid 6. (637 aa) | ||||
pkd2 | Ubiquitin carboxyl-terminal hydrolase 33. (951 aa) | ||||
hs2st1 | LOC100145562 protein. (356 aa) | ||||
rtn4rl1-3 | Reticulon 4 receptor-like 1. (414 aa) | ||||
anks6 | Uncharacterized protein. (903 aa) | ||||
LOC101732240 | Poly [ADP-ribose] polymerase. (492 aa) | ||||
LOC100494987 | Uncharacterized protein. (485 aa) | ||||
serpinf1 | Serine (Or cysteine) proteinase inhibitor, clade F, member 1; Belongs to the serpin family. (409 aa) | ||||
NUP133 | Nucleoporin 133. (1142 aa) | ||||
slit2 | ATPase family, AAA domain containing 3A. (1564 aa) | ||||
LOC100145507 | LOC100145507 protein. (684 aa) | ||||
eaf2 | Helicase with zinc finger. (297 aa) | ||||
foxc1 | Forkhead box protein C1; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Required for cell viability and resistance to oxidative stress in the eye. Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1- mediated signals. Involved in epi [...] (495 aa) | ||||
prkx | Uncharacterized protein; Belongs to the protein kinase superfamily. (369 aa) | ||||
smad4.1 | Mothers against decapentaplegic homolog. (579 aa) | ||||
tshz1 | Tetraspanin 2. (1095 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (293 aa) | ||||
WDPCP | WD repeat containing planar cell polarity effector. (708 aa) | ||||
mpst | Sulfurtransferase. (299 aa) | ||||
mtss1.1 | Gephyrin. (722 aa) | ||||
ift27 | Uncharacterized protein. (210 aa) | ||||
frs2-2 | Frs2 protein. (509 aa) | ||||
SGPL1 | Sphingosine-1-phosphate lyase 1. (573 aa) | ||||
crlf1 | Mitochondrial E3 ubiquitin protein ligase 1. (387 aa) | ||||
fem1b | Discs, large homolog-associated protein 3. (681 aa) | ||||
CNTRL | Centriolin. (2247 aa) | ||||
dll1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (740 aa) | ||||
tsc1 | Distal-less homeobox 1. (1139 aa) | ||||
wt1 | Wilms tumor protein homolog; Transcription factor required for development of the vascular component of the pronephric kidney, the glomus; may repress tubule- specific gene expression in the portion of the pronephros fated to form the glomus (By similarity). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (By similarity). Inhibits Wnt-signaling during embryonic development (By similarity); Belongs to the EGR C2H2-type zinc-finger protein family. (452 aa) | ||||
zmpste24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (472 aa) | ||||
osr2 | Podocan. (312 aa) | ||||
lrp4 | Glycoprotein A33 (transmembrane). (1832 aa) | ||||
HNF1B | HNF1 homeobox B. (566 aa) | ||||
NPHS1 | NPHS1 adhesion molecule, nephrin. (1078 aa) | ||||
ap1b1 | AP complex subunit beta. (946 aa) | ||||
gcnt1 | Coiled-coil domain containing 77. (426 aa) | ||||
gli3 | Centrosomal protein 164kDa. (1566 aa) | ||||
hells | Uncharacterized protein. (840 aa) | ||||
Smad6.2 | MH2 domain-containing protein. (206 aa) | ||||
ar | Transforming acidic coiled-coil containing protein 3. (788 aa) | ||||
TTC8 | Tetratricopeptide repeat domain 8. (516 aa) | ||||
AHI1 | Abelson helper integration site 1. (747 aa) | ||||
kif26b | Glycogenin 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2097 aa) | ||||
dlc | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa) | ||||
hoxa11 | Lamin B1. (299 aa) | ||||
scamp5.2 | Homeobox domain-containing protein. (90 aa) | ||||
agtr1 | Agtr1.2 protein; Belongs to the G-protein coupled receptor 1 family. (355 aa) | ||||
pecam1 | Uncharacterized protein. (726 aa) | ||||
jmjd6 | JmjC domain-containing protein. (403 aa) | ||||
basp1 | Brain abundant, membrane attached signal protein 1. (238 aa) | ||||
c1galt1 | Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (354 aa) | ||||
zbtb16 | Collagen, type IX, alpha 3. (660 aa) | ||||
wfs1 | LOC100127642 protein. (863 aa) | ||||
tfap2a | Beta-1,4-N-acetyl-galactosaminyl transferase 1. (451 aa) | ||||
IFT88 | Intraflagellar transport 88. (826 aa) | ||||
SOX8 | SRY-box transcription factor 8. (466 aa) | ||||
tgfb1 | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) | ||||
sulf1 | Uncharacterized protein. (1145 aa) | ||||
wnt11-2 | Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Shares much functionality with wnt11b. Signals through a non-canonical Wnt pathway to activate Jun-N- terminal kinase (JNK) to regulate gastrulation movements. Acts in a non-cell-autonomous manner to control neural crest migration, probably acting as an extracellular signal from surrounding tissue, but is not required for neural crest induction. Acts redundantly with wnt11b during pronephros induction. Regulates cardiac morphogenesis through the activation of JNK, but is not requ [...] (352 aa) | ||||
zfp36l2 | mRNA decay activator protein ZFP36L2; Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis (By similarity). Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery (By similarity). Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-con [...] (362 aa) | ||||
fgf8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) | ||||
tns2 | Erythrocyte membrane protein band 4.1-like 1. (1239 aa) | ||||
traf3ip3 | TRAF3 interacting protein 2. (333 aa) | ||||
ZBTB14 | Zinc finger and BTB domain containing 14. (452 aa) | ||||
tfap2b | Methionine adenosyltransferase II, alpha. (464 aa) | ||||
pdgfb-2 | Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa) | ||||
RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1101 aa) | ||||
NF1 | Neurofibromin 1. (2812 aa) | ||||
dchs2 | Uncharacterized protein. (3254 aa) | ||||
efnb2 | Solute carrier family 41 member 2; Belongs to the ephrin family. (329 aa) | ||||
jag1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) | ||||
lrrk2 | Hes family bHLH transcription factor 2. (2514 aa) | ||||
bag6 | Large proline-rich protein bag6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the bag6/bat3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endo [...] (1135 aa) | ||||
irx1 | Iroquois-class homeodomain protein irx-1; Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Acts early in neural plate development to induce expression of some but not all proneural genes, and specify a neural precursor state. Also up- regulates repressors that prevent neuronal differentiation. Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes. Acts primarily as a transcriptional repressor during neural development, and binds [...] (467 aa) | ||||
bmp4 | Zinc finger, HIT-type-containing 6. (469 aa) | ||||
ace | Angiotensin-converting enzyme. (1337 aa) | ||||
LOC100496837 | GDNF family receptor alpha 2. (348 aa) | ||||
LOC100486174 | Solute carrier family 13 member 4 like. (334 aa) | ||||
LOC100486323 | Transmembrane protein 143. (321 aa) | ||||
lrp2 | Rab geranylgeranyltransferase subunit beta. (4662 aa) | ||||
dnajc15 | DnaJ homolog subfamily C member 15; Negative regulator of the mitochondrial respiratory chain (By similarity). Plays a role in the translocation of proteins across the mitochondrial inner membrane (By similarity). Involved in pronephric kidney development at the early tadpole stage. (187 aa) | ||||
tcf21 | Transcription factor 21; Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. (179 aa) | ||||
triap1 | TP53-regulated inhibitor of apoptosis 1; Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. The triap1:prelid1 complex probably functions as a phosphatidic acid (PA) transporter across the mitochondrion intermembrane space to provide PA for cardiolipin CL synthesis in the inner membrane. Likewise, the triap1:prelid3a complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo [...] (78 aa) | ||||
bmper | Uncharacterized protein. (741 aa) | ||||
kank2 | CLIP-associating protein 1. (887 aa) | ||||
pkd1 | L-threonine dehydrogenase (pseudogene). (4091 aa) | ||||
PYGO1 | Pygopus family PHD finger 1. (506 aa) | ||||
wnt11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) | ||||
AMH | Anti-Mullerian hormone. (606 aa) | ||||
wnt4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) | ||||
gdnf | Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (227 aa) | ||||
spry1 | Mitochondrial amidoxime reducing component 1. (342 aa) | ||||
fgf2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa) | ||||
enpep | Aminopeptidase. (961 aa) | ||||
ilk | Uncharacterized protein. (286 aa) | ||||
acvr1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (568 aa) | ||||
prdm1 | ChaC, cation transport regulator homolog 2. (784 aa) | ||||
osr1 | Protein odd-skipped-related 1; Transcriptional repressor (By similarity). Required for pronephric kidney development. (215 aa) | ||||
cpeb3 | Cytoplasmic polyadenylation element-binding protein 3; Sequence-specific RNA-binding protein which acts as a translational repressor in the basal unstimulated state but, following neuronal stimulation, acts as a translational activator (By similarity). Does not bind to the cytoplasmic polyadenylation element (CPE), a uridine-rich sequence element within the mRNA 3'-UTR, but binds to a U-rich loop within a stem-loop structure (By similarity). Required for the consolidation and maintenance of hippocampal-based long term memory (By similarity). Inhibits differentiation of intermediate mes [...] (603 aa) | ||||
wnt9b.2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (337 aa) | ||||
nphp3 | Nephrocystin-3; Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling that regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements (By similarity). (1266 aa) | ||||
TBC1D32 | TBC1 domain family member 32. (1300 aa) | ||||
bax | BCL2-associated X protein. (221 aa) | ||||
nup107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (916 aa) | ||||
tmem59l | LOC100158571 protein. (335 aa) | ||||
ednrb | Aconitase 2; Belongs to the G-protein coupled receptor 1 family. (433 aa) | ||||
kctd1 | Potassium channel tetramerization domain containing 1. (302 aa) | ||||
bcl2l11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (194 aa) | ||||
ap2b1 | AP complex subunit beta. (970 aa) | ||||
K9J7P7_XENTR | Uncharacterized protein. (167 aa) | ||||
SMAD7 | Mothers against decapentaplegic homolog. (382 aa) | ||||
smad3 | Mothers against decapentaplegic homolog. (461 aa) | ||||
BICC1 | BicC family RNA binding protein 1. (918 aa) | ||||
SMAD6 | Mothers against decapentaplegic homolog. (352 aa) | ||||
RPGRIP1L | RPGRIP1 like. (1266 aa) | ||||
irx3 | Iroquois-class homeodomain protein irx-3; Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Both up- regulates and down-regulates gene expression during neural development. Acts early in neural plate development to induce proneural gene expression and specify a neural precursor state. Also up-regulates repressors that prevent neuronal differentiation. Required during at least two stages of pronephros kidney development; during neurula stages, maintains tran [...] (448 aa) | ||||
smad2 | Mothers against decapentaplegic homolog. (467 aa) | ||||
FREM2 | FRAS1 related extracellular matrix 2. (3126 aa) | ||||
usp7-2 | Ubiquitin specific peptidase 7 (herpes virus-associated). (316 aa) | ||||
GLIS2 | GLIS family zinc finger 2. (493 aa) | ||||
ptpro | ORMDL sphingolipid biosynthesis regulator 1. (1018 aa) | ||||
dchs1 | Uncharacterized protein. (2586 aa) | ||||
ARL3 | ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (195 aa) | ||||
rara | Uncharacterized protein. (564 aa) | ||||
HOXC11 | Homeobox C11. (309 aa) | ||||
sox7 | Transcription factor Sox-7; Transcription factor. Binds to the DNA sequence 5'-AACAAT-3'. Acts downstream of vegt and upstream of nodal signaling to promote endodermal and mesodermal differentiation by promoting vegt-induced expression of both endodermal genes (including endodermin) and mesodermal genes (including snai1/snail and snai2/slug). Induces expression of multiple nodal genes (including nodal, nodal2, nodal4, nodal5 and nodal6) and binds directly to sites within the promoter of the nodal5 gene. The endodermal and mesodermal specification pathways then interact to initiate card [...] (362 aa) | ||||
gzf1 | GDNF-inducible zinc finger protein 1. (697 aa) | ||||
fgf1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) | ||||
bmp6 | Enhancer of mRNA decapping 4. (441 aa) | ||||
rarg | Nucleoporin like 2. (476 aa) | ||||
bmp2 | Armadillo like helical domain containing 3. (398 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa) | ||||
cirbp | Cold-inducible RNA-binding protein; Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to themm and inhibiting their deadenylation. Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules, and cell movement during embryogenesis. Required for pronephros development (By similarity). (198 aa) | ||||
stk11 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (442 aa) | ||||
PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (3166 aa) | ||||
LOC100485879 | Taste 1 receptor member 1. (357 aa) | ||||
LOC100486030 | Uncharacterized protein. (311 aa) |