STRINGSTRING
scarb1 scarb1 loxl4 loxl4 prok1 prok1 prok2 prok2 pik3cb pik3cb avpr2.2-2 avpr2.2-2 bmper bmper itgb1bp1 itgb1bp1 xbp1 xbp1 NF1 NF1 NOX5 NOX5 prkx prkx tgfbr1 tgfbr1 cav3.2 cav3.2 TEK TEK vstm4 vstm4 cav3.1 cav3.1 cav2 cav2 cav1 cav1 loxl2 loxl2 BMPR2 BMPR2 fgf7 fgf7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
scarb1Coagulation factor 12 (Hageman factor); Belongs to the CD36 family. (450 aa)
loxl4Cell division cycle 5 like. (731 aa)
prok1Receptor tyrosine kinase-like orphan receptor 1. (106 aa)
prok2Neurofilament heavy. (209 aa)
pik3cbSolute carrier family 27 member 6; Belongs to the PI3/PI4-kinase family. (1085 aa)
avpr2.2-2Arginine vasopressin receptor 2 (nephrogenic diabetes insipidus), gene 2. (508 aa)
bmperUncharacterized protein. (741 aa)
itgb1bp1Ficolin 1. (209 aa)
xbp1Destrin, actin depolymerizing factor. (349 aa)
NF1Neurofibromin 1. (2812 aa)
NOX5NADPH oxidase 5. (737 aa)
prkxUncharacterized protein; Belongs to the protein kinase superfamily. (369 aa)
tgfbr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
cav3.2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
TEKTEK receptor tyrosine kinase. (1114 aa)
vstm4Zinc finger protein 385C. (347 aa)
cav3.1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (160 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
loxl2Lysyl oxidase homolog 2; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Shows no activity against histone H3 when it is trimethylated on 'Lys- 9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2). Also mediates deamination of methylated TAF10, a member o [...] (786 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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