STRINGSTRING
ENSXETP00000000456 ENSXETP00000000456 sec31a-2 sec31a-2 stim1 stim1 tnf tnf selenos selenos ENSXETP00000001570 ENSXETP00000001570 sri sri sart3 sart3 ADAMTS4 ADAMTS4 twnk twnk MALT1 MALT1 itih5-2 itih5-2 ntrk2 ntrk2 F3 F3 bdkrb2 bdkrb2 ITGA3 ITGA3 riok3 riok3 polg polg fn1 fn1 amfr amfr bcl2l10 bcl2l10 dpp4 dpp4 rnf139 rnf139 RIPK2 RIPK2 cltc cltc vwf vwf itgb3 itgb3 LOC101734901 LOC101734901 pzp pzp LOC100489060 LOC100489060 cradd.2 cradd.2 cflar cflar a2ml1 a2ml1 lonp2 lonp2 bcl10 bcl10 anxa2 anxa2 LOC100490322 LOC100490322 ENSXETP00000011099 ENSXETP00000011099 bfar bfar SERPINF2 SERPINF2 CASP8AP2 CASP8AP2 brca2 brca2 pdzd3 pdzd3 tpm3 tpm3 chmp3-2 chmp3-2 ecm1 ecm1 fbxo45 fbxo45 thnsl2-2 thnsl2-2 yipf5 yipf5 slc2a13 slc2a13 sspo sspo itgav itgav CCBE1 CCBE1 pycard pycard cltcl1 cltcl1 psap psap cd28 cd28 ENSXETP00000024798 ENSXETP00000024798 flot1 flot1 fadd fadd trip4 trip4 SH3PXD2A SH3PXD2A cradd.1 cradd.1 LOC100488897 LOC100488897 ovos2 ovos2 derl1 derl1 czib-2 czib-2 zyg11b-2 zyg11b-2 rab3b-2 rab3b-2 nubp1-2 nubp1-2 loc100290309 loc100290309 LOC100495470 LOC100495470 kit kit a2m a2m timp2 timp2 tmtc3-2 tmtc3-2 BCL2 BCL2 SERPINE1 SERPINE1 marchf6 marchf6 flot2 flot2 ENSXETP00000038003 ENSXETP00000038003 tysnd1 tysnd1 tgfb1-2 tgfb1-2 tcerg1-2 tcerg1-2 bach2-2 bach2-2 tp53 tp53 gatd1 gatd1 timp3 timp3 nfrkb nfrkb seh1l-2 seh1l-2 pcasp3 pcasp3 serpinc1 serpinc1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSXETP00000000456Uncharacterized protein. (198 aa)
sec31a-2Uncharacterized protein. (1032 aa)
stim1SAM domain-containing protein. (789 aa)
tnfThyrotropin-releasing hormone receptor 3. (227 aa)
selenosSelenoprotein S; Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner (By similarity). (189 aa)
ENSXETP00000001570Mediator of RNA polymerase II transcription subunit 8. (574 aa)
sriSorcin. (195 aa)
sart3HMG-box transcription factor 1. (661 aa)
ADAMTS4ADAM metallopeptidase with thrombospondin type 1 motif 4. (852 aa)
twnkV-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G. (677 aa)
MALT1MALT1 paracaspase. (799 aa)
itih5-2Leucine rich repeat containing 41. (180 aa)
ntrk2Tyrosine-protein kinase receptor. (821 aa)
F3Coagulation factor III, tissue factor. (282 aa)
bdkrb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; Belongs to the G-protein coupled receptor 1 family. (371 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1046 aa)
riok3Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (508 aa)
polgTyrosylprotein sulfotransferase 1. (1197 aa)
fn1Fibronectin 1. (2475 aa)
amfrUncharacterized protein. (644 aa)
bcl2l10Uncharacterized protein. (174 aa)
dpp4Uncharacterized protein; Belongs to the peptidase S9B family. (837 aa)
rnf139Ring finger protein 139. (663 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (408 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1692 aa)
vwfNADH:ubiquinone oxidoreductase core subunit S8. (2627 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (800 aa)
LOC101734901Uncharacterized protein. (1358 aa)
pzpUncharacterized protein. (1443 aa)
LOC100489060Leucine rich repeat containing 2. (1437 aa)
cradd.2Colony stimulating factor 2 receptor beta common subunit. (197 aa)
cflarUncharacterized protein; Belongs to the peptidase C14A family. (523 aa)
a2ml1Uncharacterized protein. (1468 aa)
lonp2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (845 aa)
bcl10Solute carrier family 35 (GDP-fucose transporter), member C2. (236 aa)
anxa2Annexin. (340 aa)
LOC100490322Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (297 aa)
ENSXETP00000011099Uncharacterized protein. (197 aa)
bfarUncharacterized protein. (448 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (594 aa)
CASP8AP2Uncharacterized protein. (1824 aa)
brca2StAR related lipid transfer domain containing 9. (3138 aa)
pdzd3STARD3 N-terminal like. (428 aa)
tpm3Tropomyosin 3. (197 aa)
chmp3-2Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Involved in late stages of cytokinesis. Plays a role in en [...] (220 aa)
ecm1O-phosphoseryl-tRNA(Sec) selenium transferase. (455 aa)
fbxo45F-box/SPRY domain-containing protein 1. (282 aa)
thnsl2-2Protein YIPF. (284 aa)
yipf5Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family. (259 aa)
slc2a13PHD finger protein 21B; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (618 aa)
sspoSCO-spondin. (4995 aa)
itgavRAB5B, member RAS oncogene family; Belongs to the integrin alpha chain family. (1034 aa)
CCBE1Collagen and calcium binding EGF domains 1. (394 aa)
pycardFamily with sequence similarity 84 member B. (199 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
psapProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (538 aa)
cd28Cd28 protein. (210 aa)
ENSXETP00000024798Uncharacterized protein. (1337 aa)
flot1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (444 aa)
faddZinc finger, NFX1-type containing 1, gene 2. (188 aa)
trip4ASCH domain-containing protein. (654 aa)
SH3PXD2ASH3 and PX domains 2A. (1111 aa)
cradd.1CASP2 and RIPK1 domain containing adaptor with death domain. (197 aa)
LOC100488897Phospholipase C like 2. (1199 aa)
ovos2Uncharacterized protein. (1438 aa)
derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (253 aa)
czib-2CXXC motif containing zinc binding protein. (236 aa)
zyg11b-2Zyg-11 family member B, cell cycle regulator. (252 aa)
rab3b-2RAB3B, member RAS oncogene family. (236 aa)
nubp1-2Cytosolic Fe-S cluster assembly factor nubp1. (248 aa)
loc100290309IgGFc-binding protein-like. (419 aa)
LOC100495470Uncharacterized protein. (2996 aa)
kitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (966 aa)
a2mTubulin alpha like 3, gene 1. (1369 aa)
timp2MGC108274 protein. (222 aa)
tmtc3-2Transmembrane and tetratricopeptide repeat containing 3. (152 aa)
BCL2BCL2 apoptosis regulator. (293 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (449 aa)
marchf6WNT inhibitory factor 1. (918 aa)
flot2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (479 aa)
ENSXETP00000038003Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (309 aa)
tysnd1Serine protease; Belongs to the peptidase S1B family. (588 aa)
tgfb1-2ALG8, alpha-1,3-glucosyltransferase. (228 aa)
tcerg1-2Transcription elongation regulator 1. (572 aa)
bach2-2BTB (POZ) domain containing 3. (1384 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa)
gatd1Eukaryotic translation initiation factor 2 alpha kinase 4. (619 aa)
timp3Chaperonin containing TCP1 subunit 8. (214 aa)
nfrkbNuclear factor related to kappa-B-binding protein; Binds to DNA; Belongs to the NFRKB family. (1033 aa)
seh1l-2Nucleoporin SEH1. (112 aa)
pcasp3Uncharacterized protein. (632 aa)
serpinc1Thioredoxin like 4B; Belongs to the serpin family. (456 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
Server load: low (28%) [HD]