STRINGSTRING
aen aen prorp prorp ENSXETP00000051695 ENSXETP00000051695 l2hgdh l2hgdh ENSXETP00000051705 ENSXETP00000051705 LOC100490587 LOC100490587 ENSXETP00000051711 ENSXETP00000051711 LOC100490758 LOC100490758 nlgn2 nlgn2 LOC780277 LOC780277 ENSXETP00000052247 ENSXETP00000052247 ago2 ago2 TATDN1 TATDN1 FAN1 FAN1 pan2 pan2 rcl1 rcl1 marf1 marf1 ENDOU ENDOU ENSXETP00000052624 ENSXETP00000052624 ERI3 ERI3 Zc3h12a Zc3h12a idi1-2 idi1-2 spopl spopl ENSXETP00000019751 ENSXETP00000019751 ENSXETP00000019857 ENSXETP00000019857 nob1 nob1 ZC3H12C ZC3H12C ENSXETP00000020723 ENSXETP00000020723 exd2 exd2 mybl2 mybl2 dclre1a dclre1a exosc10-2 exosc10-2 N4BP2 N4BP2 rexo4 rexo4 c12orf10 c12orf10 eme2 eme2 ttc38 ttc38 POP5 POP5 endoul2 endoul2 lactb2 lactb2 LOC100496720 LOC100496720 meiob meiob rexo5 rexo5 TSEN34 TSEN34 drosha drosha endov endov zranb3 zranb3 kank2-2 kank2-2 LOC100487906 LOC100487906 pld6 pld6 dis3l dis3l psmb1-2 psmb1-2 aste1 aste1 aplf aplf TATDN3 TATDN3 angel2 angel2 apex2 apex2 trir trir piwil4 piwil4 pld3 pld3 slx1a slx1a xrn1 xrn1 ddx1 ddx1 usb1 usb1 parn parn elac1 elac1 nmbr-2 nmbr-2 LOC101732272 LOC101732272 zgrf1 zgrf1 endoul endoul mrps15-3 mrps15-3 exosc10 exosc10 dffb dffb pelo pelo rnaseh2a rnaseh2a rpp40 rpp40 fen1 fen1 letm1 letm1 n4bp2l1 n4bp2l1 xrn2 xrn2 rpp21 rpp21 cpsf3 cpsf3 piwil3 piwil3 isg20l2 isg20l2 LOC100135188 LOC100135188 thbs4-2 thbs4-2 dcp2 dcp2 dxo dxo DNA2 DNA2 pold1 pold1 RPP38 RPP38 ercc5 ercc5 piwil2 piwil2 dbr1 dbr1 rnaseh1 rnaseh1 MGC146443 MGC146443 rexo2 rexo2 ern2 ern2 LOC101731854 LOC101731854 tdp1 tdp1 rad9a rad9a cnot7 cnot7 apex1 apex1 mrpl44 mrpl44 rad51c rad51c mus81 mus81 DCLRE1C DCLRE1C ERI2 ERI2 dnase2b dnase2b dis3 dis3 tdp2 tdp2 F6XXJ1_XENTR F6XXJ1_XENTR toe1 toe1 LOC101734301 LOC101734301 rida rida POP1 POP1 enpp2 enpp2 LOC100496462 LOC100496462 psen2-2 psen2-2 Rnase4 Rnase4 khnyn khnyn FANCM FANCM RPP25 RPP25 n4bp1 n4bp1 g3bp1 g3bp1 dnase1l2 dnase1l2 LOC100494905 LOC100494905 GEN1 GEN1 SAMHD1 SAMHD1 ints11 ints11 trex2 trex2 hepacam2 hepacam2 piwil1 piwil1 pole pole mre11 mre11 ERCC4 ERCC4 rps3 rps3 ENDOD1 ENDOD1 snd1 snd1 harbi1 harbi1 sparc-2 sparc-2 fscn2-2 fscn2-2 rad1 rad1 EXD3 EXD3 LOC100497175 LOC100497175 rad51c-2 rad51c-2 pop4 pop4 LOC100495727 LOC100495727 LOC101731382 LOC101731382 helz2 helz2 mblac1 mblac1 ankle1 ankle1 mep1a-2 mep1a-2 rexo1 rexo1 smg6 smg6 gjb3-2 gjb3-2 eri1 eri1 noct noct rag1 rag1 wrn wrn RAD9B RAD9B ltb4r2-2 ltb4r2-2 aptx aptx dclre1b dclre1b ago1 ago1 las1l las1l zc3h12b zc3h12b pnpt1 pnpt1 nudt16 nudt16 dnase1l3 dnase1l3 ago4 ago4 LRRC27 LRRC27 nudt12 nudt12 ube2d4-2 ube2d4-2 cnot6l cnot6l LOC100036702 LOC100036702 eme1 eme1 LOC100127659 LOC100127659 dnase2 dnase2 RNASEK RNASEK YBEY YBEY ENPP1 ENPP1 dis3l2 dis3l2 endog endog setmar setmar exo1 exo1 ENPP3 ENPP3 rpp30 rpp30 dicer1 dicer1 nono-2 nono-2 mgme1 mgme1 cnot8 cnot8 rnaset2 rnaset2 PDE12 PDE12 rbbp8 rbbp8 polg polg
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aenExonuclease domain-containing protein. (360 aa)
prorpChromosome 1 open reading frame 21. (583 aa)
ENSXETP00000051695Uncharacterized protein. (265 aa)
l2hgdhL-2-hydroxyglutarate dehydrogenase. (214 aa)
ENSXETP00000051705Uncharacterized protein. (299 aa)
LOC100490587Hyaluronan binding protein 2. (314 aa)
ENSXETP00000051711Uncharacterized protein. (252 aa)
LOC100490758Uncharacterized protein. (337 aa)
nlgn2Uncharacterized protein. (299 aa)
LOC780277Lysophosphatidic acid receptor 2. (297 aa)
ENSXETP00000052247Endo/exonuclease/phosphatase domain-containing protein. (242 aa)
ago2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (894 aa)
TATDN1TatD DNase domain containing 1. (329 aa)
FAN1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1012 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1210 aa)
rcl1SPT6 homolog, histone chaperone. (372 aa)
marf1Meiosis regulator and mRNA stability factor 1; Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. (1682 aa)
ENDOUPoly(U)-specific endoribonuclease. (418 aa)
ENSXETP00000052624Endo/exonuclease/phosphatase domain-containing protein. (437 aa)
ERI3ERI1 exoribonuclease family member 3. (321 aa)
Zc3h12aC3H1-type domain-containing protein. (349 aa)
idi1-2Isopentenyl-diphosphate delta isomerase 1. (290 aa)
spoplSpeckle type POZ protein like. (436 aa)
ENSXETP00000019751SCAN box domain-containing protein. (762 aa)
ENSXETP00000019857Uncharacterized protein. (181 aa)
nob1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (436 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (884 aa)
ENSXETP00000020723DDE Tnp4 domain-containing protein. (346 aa)
exd2Phospholipase A2 group IB. (642 aa)
mybl2MYB proto-oncogene like 2. (344 aa)
dclre1aT-box transcription factor TBX1. (960 aa)
exosc10-2Exosome component 10. (127 aa)
N4BP2NEDD4 binding protein 2. (1502 aa)
rexo4RNA exonuclease 4. (414 aa)
c12orf10Melanocyte proliferating gene 1. (369 aa)
eme2Probable crossover junction endonuclease EME2; Interacts with mus81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures. (503 aa)
ttc38Tetratricopeptide repeat protein 38; Belongs to the TTC38 family. (479 aa)
POP5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (165 aa)
endoul2XendoU domain-containing protein. (306 aa)
lactb2Endoribonuclease LACTB2; Endoribonuclease; cleaves preferentially 3' to purine- pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double- stranded RNA or DNA. Required for normal mitochondrial function and cell viability. (317 aa)
LOC100496720Notum, palmitoleoyl-protein carboxylesterase. (505 aa)
meiobSolute carrier family 12 (potassium/chloride transporter), member 4. (480 aa)
rexo5Nkx1-1. (787 aa)
TSEN34tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (308 aa)
droshaKruppel-like factor 8. (1382 aa)
endovCytosolic purine 5'-nucleotidase. (227 aa)
zranb3RE1 silencing transcription factor. (1081 aa)
kank2-2Deoxyribonuclease; Belongs to the DNase I family. (293 aa)
LOC100487906DDE Tnp4 domain-containing protein. (350 aa)
pld6Mitochondrial cardiolipin hydrolase; Regulates mitochondrial shape through facilitating mitochondrial fusion. During spermatogenesis, plays a critical role in PIWI-interacting RNA (piRNA) biogenesis (By similarity). piRNAs provide essential protection against the activity of mobile genetic elements. piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation. Has been shown to be a backbone-non-specific, single strand-specific nuclease, cleavin [...] (210 aa)
dis3lDIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. (1061 aa)
psmb1-2Proteasome subunit beta 1; Belongs to the pancreatic ribonuclease family. (165 aa)
aste1XPG_I_2 domain-containing protein. (663 aa)
aplfUncharacterized protein. (509 aa)
TATDN3TatD DNase domain containing 3. (273 aa)
angel2La ribonucleoprotein domain family member 4. (526 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (563 aa)
trirLOC100145043 protein. (243 aa)
piwil4Branched chain keto acid dehydrogenase E1, beta polypeptide; Belongs to the argonaute family. (822 aa)
pld35'-3' exonuclease PLD3; 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (By similarity). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity). May be important in myotube formation. Plays a role in lysosomal homeostasis. Involved in the regulation of endosomal protein sorting (By similarity). (503 aa)
slx1aStructure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (277 aa)
xrn1Ribosomal protein L29. (1740 aa)
ddx1ATP-dependent RNA helicase DDX1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Acts as a positive regulator of transcription. May be involved in 3'-end cleavage and polyadenylation of pre-mRNAs. Binds DNA and RNA. Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit rtcb. Binds (via helicase ATP-binding domain) on both short and long poly(I:C) dsRNA (By similarity); Belongs to the DEAD box helicase family. DDX1 subfamily. (737 aa)
usb1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (251 aa)
parnQKI, KH domain containing, RNA binding. (632 aa)
elac1Elac1 (Prov). (363 aa)
nmbr-2Neuromedin B receptor. (327 aa)
LOC101732272Ribophorin I. (284 aa)
zgrf1Uncharacterized protein. (1945 aa)
endoulPoly(U)-specific endoribonuclease; Poly(U)-specific endoribonuclease involved in the biosynthesis of intron-encoded box C/D snoRNAs, such as U16 and U86. Releases products that have 2'-3'-cyclic phosphate termini (By similarity); Belongs to the ENDOU family. (317 aa)
mrps15-3Uncharacterized protein. (1169 aa)
exosc10Sigma non-opioid intracellular receptor 1. (891 aa)
dffbGPALPP motifs containing 1. (380 aa)
peloUncharacterized protein. (290 aa)
rnaseh2aRibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (303 aa)
rpp40Shootin 1. (359 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa)
letm1Mitochondrial proton/calcium exchanger protein; Mitochondrial proton/calcium antiporter that mediates proton- dependent calcium efflux from mitochondrion (By similarity). Required for the maintenance of the tubular shape and cristae organization (By similarity). (766 aa)
n4bp2l1Tau tubulin kinase 2. (224 aa)
xrn25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (960 aa)
rpp21Ribonuclease P 21kDa subunit. (154 aa)
cpsf3Uncharacterized protein. (692 aa)
piwil3Uncharacterized protein; Belongs to the argonaute family. (869 aa)
isg20l2Ankyrin repeat domain 45. (432 aa)
LOC100135188Junction-mediating and -regulatory protein. (371 aa)
thbs4-2Thrombospondin 4. (397 aa)
dcp2Nudix hydrolase domain-containing protein. (487 aa)
dxoRAI1 domain-containing protein. (488 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2; Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape fen1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit dna2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by [...] (1100 aa)
pold1DNA polymerase. (1191 aa)
RPP38Ribonuclease P/MRP subunit p38. (261 aa)
ercc5Basic immunoglobulin-like variable motif-containing protein. (1395 aa)
piwil2Piwi-like protein 2; Endoribonuclease that plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. During [...] (949 aa)
dbr1Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. (534 aa)
rnaseh1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (302 aa)
MGC146443Leucine-rich repeat-containing 1. (204 aa)
rexo2LRP2 binding protein. (273 aa)
ern2Endoplasmic reticulum to nucleus signaling 2. (957 aa)
LOC101731854Uncharacterized protein. (294 aa)
tdp1Uncharacterized protein. (606 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (379 aa)
cnot7CCR4-NOT transcription complex subunit 7; Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA- mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence [...] (285 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (363 aa)
mrpl44Hypothetical LOC496841. (322 aa)
rad51cMalignant T-cell-amplified sequence 1. (369 aa)
mus81Crossover junction endonuclease MUS81; Interacts with eme1 and eme2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks (By similarity); Belongs to the XPF family. (612 aa)
DCLRE1CDNA cross-link repair 1C. (721 aa)
ERI2ERI1 exoribonuclease family member 2. (695 aa)
dnase2bDeoxyribonuclease II beta. (340 aa)
dis3Uncharacterized protein; Belongs to the RNR ribonuclease family. (998 aa)
tdp2Tyrosyl-DNA phosphodiesterase 2; DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead- end complexes between DNA and the topoisomerase 2 (top2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. (369 aa)
F6XXJ1_XENTRDDE Tnp4 domain-containing protein. (281 aa)
toe1C3H1-type domain-containing protein. (513 aa)
LOC101734301STAM binding protein like 1. (365 aa)
ridaHeat-responsive protein 12. (139 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (1037 aa)
enpp2Uncharacterized protein. (922 aa)
LOC100496462RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (165 aa)
psen2-2Presenilin 2; Belongs to the pancreatic ribonuclease family. (122 aa)
Rnase4Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1. (178 aa)
khnynRNase_Zc3h12a domain-containing protein. (841 aa)
FANCMFA complementation group M. (2232 aa)
RPP25Ribonuclease P and MRP subunit p25. (168 aa)
n4bp1NEDD4-binding protein 1; Inhibitor of the E3 ubiquitin-protein ligase itch. Belongs to the N4BP1 family. (819 aa)
g3bp1Formin homology 2 domain containing 1. (507 aa)
dnase1l2Deoxyribonuclease; Belongs to the DNase I family. (288 aa)
LOC100494905Heat shock protein family D (Hsp60) member 1. (269 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (927 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (630 aa)
ints11Uncharacterized protein. (633 aa)
trex2Protein CWC15 homolog. (230 aa)
hepacam2Thyroid peroxidase. (572 aa)
piwil1CD74 molecule; Belongs to the argonaute family. (861 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2298 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (709 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (930 aa)
rps3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (246 aa)
ENDOD1Endonuclease domain containing 1. (448 aa)
snd1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (912 aa)
harbi1Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1). (347 aa)
sparc-2Secreted protein, acidic, cysteine-rich (osteonectin). (173 aa)
fscn2-2Myotubularin related protein 10. (792 aa)
rad1RAD1 homolog (S. pombe). (281 aa)
EXD3Exonuclease 3'-5' domain containing 3. (675 aa)
LOC100497175Deoxyribonuclease; Belongs to the DNase I family. (298 aa)
rad51c-2RECA_2 domain-containing protein. (121 aa)
pop4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (223 aa)
LOC100495727Uncharacterized protein. (191 aa)
LOC101731382Uncharacterized protein. (211 aa)
helz2T-box 21. (1275 aa)
mblac1Transglutaminase 1. (226 aa)
ankle1Uncharacterized protein. (1380 aa)
mep1a-2N-terminal Xaa-Pro-Lys N-methyltransferase 1. (136 aa)
rexo1Crystallin beta A2. (1129 aa)
smg6Mitochondrial genome maintenance exonuclease 1. (1392 aa)
gjb3-2Uncharacterized protein. (128 aa)
eri1SAP domain-containing protein. (345 aa)
noctCCR4 carbon catabolite repression 4-like (S. cerevisiae). (458 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (584 aa)
wrnCell death-inducing p53-target protein 1. (1432 aa)
RAD9BRAD9 checkpoint clamp component B. (307 aa)
ltb4r2-2Deoxyribonuclease I. (339 aa)
aptxAprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...] (347 aa)
dclre1bHeat shock protein family A (Hsp70) member 5. (517 aa)
ago1Protein tyrosine phosphatase receptor type S; Belongs to the argonaute family. (880 aa)
las1lUncharacterized protein. (589 aa)
zc3h12bC-terminal binding protein 1. (854 aa)
pnpt1F-box DNA helicase 1. (789 aa)
nudt16Solute carrier family 45 member 2. (213 aa)
dnase1l3Frizzled class receptor 4. (318 aa)
ago4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (884 aa)
LRRC27Leucine rich repeat containing 27. (440 aa)
nudt12Paired like homeobox 2B. (458 aa)
ube2d4-2Carbohydrate (chondroitin 4) sulfotransferase 12. (420 aa)
cnot6lHepatocyte nuclear factor 4 gamma. (587 aa)
LOC100036702Exonuclease domain-containing protein. (1053 aa)
eme1ERCC4 domain-containing protein. (317 aa)
LOC100127659Cytosolic Fe-S cluster assembly factor nubp2. (363 aa)
dnase2Deoxyribonuclease II, lysosomal. (352 aa)
RNASEKRibonuclease K. (101 aa)
YBEYYbeY metalloendoribonuclease. (177 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (845 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (812 aa)
endogEndonuclease. (293 aa)
setmarSolute carrier family 26 (anion exchanger), member 11. (284 aa)
exo1Ubiquitin-fold modifier conjugating enzyme 1. (736 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (828 aa)
rpp30Uncharacterized protein. (303 aa)
dicer1Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...] (1899 aa)
nono-2Non-POU domain containing, octamer binding. (527 aa)
mgme1Mitochondrial genome maintenance exonuclease 1; Single-stranded DNA (ssDNA) metal-dependent exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells (By similarity). (347 aa)
cnot8CCR4-NOT transcription complex, subunit 8. (289 aa)
rnaset2Uncharacterized protein; Belongs to the RNase T2 family. (228 aa)
PDE12Phosphodiesterase 12. (537 aa)
rbbp8DNA endonuclease RBBP8; Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. (856 aa)
polgTyrosylprotein sulfotransferase 1. (1197 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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