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| | gucy2d | Guanylate cyclase. (1081 aa) |
| | efemp2 | Trichoplein, keratin filament binding. (142 aa) |
| | LOC100490464 | WD repeat domain 41; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (843 aa) |
| | nppc | Uncharacterized protein. (128 aa) |
| | dck.2 | Dpy-19-like 4. (265 aa) |
| | ACOT11 | Acyl-CoA thioesterase 11. (593 aa) |
| | atp5pd | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (170 aa) |
| | ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (845 aa) |
| | elovl5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (295 aa) |
| | pank1 | Cell death inducing DFFA like effector a. (579 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (231 aa) |
| | atic | MGS domain-containing protein. (607 aa) |
| | hk2 | Mannosyl-oligosaccharide glucosidase. (937 aa) |
| | elovl1 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (290 aa) |
| | faf2 | FAS-associated factor 2; Plays an important role in endoplasmic reticulum associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Involved in inhibition of lipid droplet degradation. (460 aa) |
| | eif3k | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (212 aa) |
| | mpc2 | Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (132 aa) |
| | pde4c | Phosphodiesterase. (801 aa) |
| | aprt | Adenine phosphoribosyltransferase. (180 aa) |
| | hepacam2 | Thyroid peroxidase. (572 aa) |
| | pank3 | LOC100135204 protein. (370 aa) |
| | ACOT8 | Acyl-CoA thioesterase 8. (317 aa) |
| | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (630 aa) |
| | ptrhd1 | Inactive serine protease PAMR1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (915 aa) |
| | adcy4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa) |
| | AMPD1 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (771 aa) |
| | ak1 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (502 aa) |
| | dmac2l | Mitochondrial ATP synthase regulatory component factor B. (199 aa) |
| | fhit | Bis(5'-adenosyl)-triphosphatase. (148 aa) |
| | NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (582 aa) |
| | galk1 | Leucine-rich repeat transmembrane protein FLRT3. (391 aa) |
| | paics.1 | AIRC domain-containing protein. (490 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1295 aa) |
| | ppat | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (540 aa) |
| | pde5a | Phosphodiesterase. (943 aa) |
| | hk1 | Uncharacterized protein. (920 aa) |
| | ak2 | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (235 aa) |
| | atp5pf | Uncharacterized protein. (125 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa) |
| | atp5md | Spermatogenesis associated 20. (59 aa) |
| | gpi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (597 aa) |
| | hddc3 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1; ppGpp hydrolyzing enzyme involved in starvation response. (179 aa) |
| | acsm3 | ATPase, class I, type 8B, member 4. (583 aa) |
| | pde4b | Phosphodiesterase. (733 aa) |
| | adss | Adenylosuccinate synthetase isozyme 2 A; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. (477 aa) |
| | NPR2 | Guanylate cyclase. (722 aa) |
| | pfas | Glutamine amidotransferase type-1 domain-containing protein. (1351 aa) |
| | nme7 | Nucleoside diphosphate kinase 7; Belongs to the NDK family. (379 aa) |
| | nt5dc1 | Uncharacterized protein. (451 aa) |
| | papss1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. (624 aa) |
| | atp5f1a | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
| | eno1 | DnaJ heat shock protein family (Hsp40) member B11. (439 aa) |
| | atp5mc1 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (170 aa) |
| | hexb-2 | Hexosaminidase B (beta polypeptide). (176 aa) |
| | ampd3 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (782 aa) |
| | cacnb4 | SH3 domain-containing protein. (550 aa) |
| | GUCY2F | Guanylate cyclase. (1133 aa) |
| | ACSL4 | Acyl-CoA synthetase long chain family member 4. (633 aa) |
| | foxk2 | Fork-head domain-containing protein. (604 aa) |
| | adssl1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. Belongs to the adenylosuccinate synthetase family. (468 aa) |
| | acot2 | Uncharacterized protein. (444 aa) |
| | cblb | E3 ubiquitin-protein ligase CBL-B; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. (982 aa) |
| | rab23 | RAB23, member RAS oncogene family. (238 aa) |
| | gtpbp1 | Choline O-acetyltransferase. (679 aa) |
| | ACSS2 | Acyl-CoA synthetase short chain family member 2. (705 aa) |
| | atp5f1d | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit. (162 aa) |
| | parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | tgfb1 | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | ppcdc | Hydroxysteroid (11-beta) dehydrogenase 1-like, gene 2. (213 aa) |
| | nudt5 | Nudix (Nucleoside diphosphate linked moiety x) type motif 5; Belongs to the Nudix hydrolase family. (221 aa) |
| | nudt8 | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease. (223 aa) |
| | DGUOK | Deoxyguanosine kinase. (265 aa) |
| | tdo2 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa) |
| | gucy1a1 | Alpha-T4 globin, Putative ortholog of hemoglobin alpha chain; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (664 aa) |
| | acot7 | TP53-regulated inhibitor of apoptosis 1. (361 aa) |
| | npr1 | Guanylate cyclase. (727 aa) |
| | aldoa | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (413 aa) |
| | tpi1 | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (268 aa) |
| | suclg2 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa) |
| | lrrk2 | Hes family bHLH transcription factor 2. (2514 aa) |
| | atp6v1b2 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (505 aa) |
| | dlst | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2) (E2K). (453 aa) |
| | fignl1 | Fidgetin-like protein 1; May be involved in DNA double-strand break (DBS) repair via homologous recombination (HR). May regulate osteoblast proliferation and differentiation (By similarity); Belongs to the AAA ATPase family. (656 aa) |
| | dhtkd1 | Thymidine kinase 1. (796 aa) |
| | stoml2 | PHB domain-containing protein. (341 aa) |
| | opa1 | Cyclin-dependent kinase inhibitor 2B; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1010 aa) |
| | ndufb2 | Chromosome 14 open reading frame 28. (102 aa) |
| | atp6v1a | Glypican 5. (596 aa) |
| | atp5mf | Uncharacterized protein. (147 aa) |
| | clk3-2 | CDC like kinase 3. (159 aa) |
| | acsl3 | Uncharacterized protein. (727 aa) |
| | adsl | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (513 aa) |
| | dck.1 | Dck protein. (265 aa) |
| | ak5 | Uncharacterized protein; Belongs to the adenylate kinase family. (557 aa) |
| | pank4 | Pantothenate kinase. (775 aa) |
| | nudt19 | Acyl-CoA synthetase short chain family member 3. (380 aa) |
| | elovl6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | atp6v1b1 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (492 aa) |
| | baat | Potassium voltage-gated channel, modifier subfamily S, member 3. (420 aa) |
| | dok5 | Elongation of very long chain fatty acids protein. (86 aa) |
| | LOC101730705 | PARP-type domain-containing protein. (102 aa) |
| | eno4 | Enolase 4; Belongs to the enolase family. (574 aa) |
| | nme5 | NDK domain-containing protein; Belongs to the NDK family. (222 aa) |
| | pgam1 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa) |
| | acsl5 | AMP-binding domain-containing protein. (329 aa) |
| | gucy1b2 | Ankyrin 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (615 aa) |
| | guk1 | EF-hand calcium-binding domain 7. (233 aa) |
| | GMPS | Guanine monophosphate synthase. (763 aa) |
| | impdh1 | Inosine-5'-monophosphate dehydrogenase 1; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (596 aa) |
| | bpgm | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa) |
| | dcakd | Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. (229 aa) |
| | gucd1 | Uncharacterized protein. (294 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (328 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (709 aa) |
| | ENSXETP00000007745 | Guanylate cyclase. (740 aa) |
| | pde4a | Phosphodiesterase. (690 aa) |
| | nudt18 | Protein phosphatase 1 regulatory subunit 3B. (329 aa) |
| | pde9a | Chromosome 16 open reading frame 72; Belongs to the cyclic nucleotide phosphodiesterase family. (344 aa) |
| | fitm2 | Fat storage-inducing transmembrane protein 2; May play a role in the regulation of cell morphology and cytoskeletal organization. Plays an important role in lipid droplet accumulation (By similarity); Belongs to the FIT family. (263 aa) |
| | pld1-2 | Phospholipase D1. (919 aa) |
| | entpd7 | Ectonucleoside triphosphate diphosphohydrolase 7; Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP (By similarity). (617 aa) |
| | atp5po | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (227 aa) |
| | LOC100216148 | Uncharacterized protein. (478 aa) |
| | atp5mg | ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (107 aa) |
| | ENSXETP00000005678 | Membrane associated ring-CH-type finger 9. (250 aa) |
| | LOC100498625 | WD repeat domain 3. (455 aa) |
| | atp5me | ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e. (71 aa) |
| | acsl6 | Uncharacterized protein. (732 aa) |
| | MGC115163 | Elongation of very long chain fatty acids protein. (277 aa) |
| | nt5c2 | Cytosolic purine 5'-nucleotidase; May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides (By similarity). (638 aa) |
| | HK2 | Hexokinase 2. (937 aa) |
| | mcm2-2 | Uncharacterized protein. (63 aa) |
| | casc3 | Protein CASC3; Required for pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs th [...] (717 aa) |
| | COASY | Coenzyme A synthase. (557 aa) |
| | nme2 | Nucleoside diphosphate kinase. (204 aa) |
| | crot | Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (612 aa) |
| | parg | Uncharacterized protein. (1107 aa) |
| | prpsap1 | LMBR1 domain containing 2. (437 aa) |
| | slc25a13 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (700 aa) |
| | acly | Leucine-rich repeat neuronal 1-like. (1121 aa) |
| | acot9 | Uncharacterized protein. (435 aa) |
| | st18-2 | ST18 C2H2C-type zinc finger transcription factor. (92 aa) |
| | nme3 | SRY-box 8; Belongs to the NDK family. (188 aa) |
| | OGDHL | Oxoglutarate dehydrogenase like. (1028 aa) |
| | LOC100489435 | Guanylate cyclase. (1103 aa) |
| | pdha1 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (402 aa) |
| | c17orf80 | Ephrin-B1. (314 aa) |
| | clpx | Uncharacterized protein. (624 aa) |
| | elovl2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (327 aa) |
| | GUCY1B1 | Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (636 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa) |
| | prpsap2 | Phosphoribosyl pyrophosphate synthase-associated protein 2; Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. (371 aa) |
| | acsl1 | Queuine tRNA-ribosyltransferase accessory subunit 2. (731 aa) |
| | twf2 | WD repeat-containing protein 82; Component of a chromatin regulatory complex involved in regulating chromatin structure in the nucleus; Belongs to the WD repeat SWD2 family. (594 aa) |
| | ATP6 | ATP synthase subunit a. (227 aa) |
| | ATP8 | ATP synthase protein 8. (55 aa) |
| | entpd4 | Novel protein similar to cornifelin; Belongs to the GDA1/CD39 NTPase family. (621 aa) |
| | LOC100497391 | LanC like 3. (582 aa) |
| | lrrc6 | Protein tilB homolog; May play a crucial role in regulating cilia motility in pronephric tubules, cloaca and neural tube. May be required for establishing left-right asymmetry of the body plan; controls cell fate and convergent extension (CE) movements during gastrulation, respectively, via the Wnt and the planar cell polarity (PCP) signaling pathways. Required for the proper development of renal glomeruli and tubules (By similarity); Belongs to the tilB family. (519 aa) |
| | elovl7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (321 aa) |
| | ENSXETP00000049648 | Uncharacterized protein. (260 aa) |
| | ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (828 aa) |
| | mvd | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa) |
| | atp5f1c | ATP synthase subunit gamma. (297 aa) |
| | NT5C1A | 5'-nucleotidase, cytosolic IA. (364 aa) |
| | oxsm | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (459 aa) |
| | pgk1 | Phosphoglycerate kinase. (418 aa) |
| | impdh2 | Inosine-5'-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (594 aa) |
| | cdh9-2 | Keratin 12, gene 6. (142 aa) |
| | LOC100495918 | Tolloid like 1. (130 aa) |
| | nppb | Cyclin-dependent kinase 11B. (137 aa) |
| | nppa | Uncharacterized protein. (143 aa) |
| | hprt1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (224 aa) |
| | gmpr | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (363 aa) |
| | wnk3 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa) |
| | gck | Phosphotransferase. (458 aa) |
| | ogdh | Transket_pyr domain-containing protein. (1033 aa) |
| | pgam2 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa) |
| | atp5mc3 | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (Subunit 9); Belongs to the ATPase C chain family. (142 aa) |
| | PDE4D | Phosphodiesterase. (719 aa) |
| | adk | Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2. (370 aa) |
| | aass | NIN1 (RPN12) binding protein 1 homolog. (964 aa) |
| | nt5dc4 | TELO2 interacting protein 1. (535 aa) |
| | pipox | Ataxin 2. (393 aa) |
| | pfkm | Uncharacterized protein. (815 aa) |
| | ndufs1 | Zinc finger protein 33B; Belongs to the complex I 75 kDa subunit family. (736 aa) |
| | PDE7A | Phosphodiesterase. (467 aa) |
| | ak3 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (221 aa) |
| | mcee | VOC domain-containing protein. (174 aa) |
| | atp5f1b | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (541 aa) |
| | pde8a | Phosphodiesterase. (823 aa) |
| | mpc2-2 | Deoxycytidine kinase, gene 2. (477 aa) |
| | mccc2 | Uncharacterized protein. (566 aa) |
| | gucy1a2 | LOC100145454 protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (712 aa) |
| | gcdh | Dolichyldiphosphatase 1. (484 aa) |
| | gpat4 | LOC100170573 protein. (453 aa) |
| | mlycd | LOC100145491 protein. (509 aa) |
| | ENSXETP00000041957 | Phosphodiesterase 9A; Belongs to the cyclic nucleotide phosphodiesterase family. (247 aa) |
| | cd99l2 | CD99 antigen-like protein 2; May function as a homophilic adhesion molecule. Belongs to the CD99 family. (250 aa) |
| | NUDT15 | Nudix hydrolase 15. (224 aa) |
| | LOC100492955 | Phosphotransferase. (600 aa) |
| | dip2a | Family with sequence similarity 83 member B. (1573 aa) |
| | uqcc3 | Secretion associated, Ras related GTPase 1B. (82 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (171 aa) |
| | pdhb | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa) |
| | nudt16 | Solute carrier family 45 member 2. (213 aa) |
| | htr2a | Solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29. (483 aa) |
| | ADPGK | ADP dependent glucokinase. (492 aa) |
| | aadat | Vitelline membrane outer layer 1 homolog. (433 aa) |
| | aldob | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (366 aa) |
| | prps2 | Ribose-phosphate pyrophosphokinase 2; Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis; Belongs to the ribose-phosphate pyrophosphokinase family. (318 aa) |
| | adcy7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1061 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (883 aa) |
| | elovl3 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (270 aa) |
| | acaca | Contactin 5. (2359 aa) |
| | nme6 | Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (179 aa) |
| | nudt4 | Nudix (Nucleoside diphosphate linked moiety X)-type motif 4. (180 aa) |
| | hsd17b4 | Uncharacterized protein. (740 aa) |
| | hmgcs1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (545 aa) |
| | PANK2 | Pantothenate kinase 2. (280 aa) |
| | LOC100145149 | Fatty acid binding protein 3. (245 aa) |
| | gmpr2 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (381 aa) |
| | aldoc | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (366 aa) |
| | bad | SMC5-SMC6 complex localization factor 1. (151 aa) |
| | EFL1 | Elongation factor like GTPase 1. (1136 aa) |
| | gapdh | Glyceraldehyde-3-phosphate dehydrogenase. (364 aa) |
| | pdhx | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (488 aa) |
| | wnt11b | Protein Wnt-11b-2; Ligand for the frizzled7 transmembrane receptor. Primarily acts via non-canonical Wnt pathways mediated by either Ca(2+) and PKC, or by JNK and dvl2/dsh. Depending on the cellular context, can also signal via the canonical Wnt pathway mediated by beta-catenin and dvl2/dsh. May also inhibit canonical Wnt signaling. Maternally initiates dorsal/ventral axis formation by a canonical route, which signals via lrp6. In a complex with wnt5a, activates the canonical and non-canonical processes involved in axis formation. In the non- canonical pathway, acts through fzd7/fz7 to [...] (353 aa) |
| | AK9 | Adenylate kinase 9. (1609 aa) |
| | ctns | Kelch like family member 24. (467 aa) |
| | dlat | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (628 aa) |
| | nmnat1 | Nicotinamide-nucleotide adenylyltransferase. (320 aa) |
| | prps1 | Pribosyltran_N domain-containing protein. (322 aa) |
| | gart | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1016 aa) |
| | nudt7 | Intersectin 1. (251 aa) |
| | ampd2 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (831 aa) |
| | mfn1 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (756 aa) |
| | gda | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (478 aa) |
| | LOC101732689 | Doublesex and mab-3 related transcription factor 3. (221 aa) |
| | acot12 | Uncharacterized protein. (476 aa) |
| | LOC101733741 | Egg envelope component ZPAX. (156 aa) |
| | LOC100496940 | Uncharacterized protein. (419 aa) |
| | tkt-2 | Transketolase. (489 aa) |
| | cox7a2l-2 | Cytochrome c oxidase subunit VIIa polypeptide 2 like. (199 aa) |
| | acacb | Leucine zipper transcription factor like 1. (2427 aa) |
| | pfkp | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (805 aa) |
| | ppcs | Thioredoxin-related transmembrane protein 1. (324 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (437 aa) |
| | LOC101734573 | Myocardial zonula adherens protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (132 aa) |
| | GUCY2C | Guanylate cyclase 2C. (1078 aa) |
| | ran | GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...] (216 aa) |
| | far1 | Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (518 aa) |
| | acss2.2 | Uncharacterized protein. (697 aa) |
| | PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2. (656 aa) |
| | pde8b | Phosphodiesterase. (816 aa) |
| | atp5pb | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1. (250 aa) |
| | PDE10A | Phosphodiesterase. (818 aa) |
