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| | gad1.1 | Matrix-remodelling-associated 5. (600 aa) |
| | ass1 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. (429 aa) |
| | ilvbl | Uncharacterized protein; Belongs to the TPP enzyme family. (651 aa) |
| | gfpt2 | Uncharacterized protein. (685 aa) |
| | SOX18 | Transcription factor Sox-18; Transcription factor. Binds to the consensus DNA sequence 5'- AACAAT-3'. Also binds 5'-CACAAT-3' and 5'-AATAAT-3' but with a lower affinity. Acts partially redundantly with sox7 during cardiogenesis, acting indirectly through nodal-signaling to induce mesodermal, organizer and endodermal tissues, which then interact to initiate cardiogenesis. Also acts as an antagonist of beta-catenin signaling (By similarity). (280 aa) |
| | LOC100496343 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (506 aa) |
| | WARS2 | Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (278 aa) |
| | ENSXETP00000011893 | THO complex subunit 4. (136 aa) |
| | ENSXETP00000011995 | TGS domain-containing protein. (152 aa) |
| | aldh18a1 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (802 aa) |
| | ctps2 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (599 aa) |
| | qrsl1 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (557 aa) |
| | FARS2 | Phenylalanyl-tRNA synthetase 2, mitochondrial. (430 aa) |
| | gcsh | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (170 aa) |
| | slc1a3 | Amino acid transporter. (542 aa) |
| | mecp2 | Kruppel-like factor 17. (466 aa) |
| | tmed8 | Fucosyltransferase 9 (alpha (1,3) fucosyltransferase). (329 aa) |
| | carnmt1-2 | Carnosine N-methyltransferase 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa) |
| | GSTZ1 | Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (216 aa) |
| | oat | Papilin, proteoglycan-like sulfated glycoprotein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa) |
| | MGC145244 | Transmembrane protein 62. (583 aa) |
| | acy1.1 | M20_dimer domain-containing protein. (382 aa) |
| | lars1 | MGC97760 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1177 aa) |
| | gatc | Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (144 aa) |
| | tph1 | Trace amine associated receptor 2 (gene/pseudogene). (494 aa) |
| | clca1.3-2 | Chloride channel accessory 1 gene 3; Belongs to the arginase family. (389 aa) |
| | kyat1 | Aminotran_1_2 domain-containing protein. (518 aa) |
| | tars2 | AA_TRNA_LIGASE_II domain-containing protein. (731 aa) |
| | psph | Uncharacterized protein. (251 aa) |
| | mtap | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (282 aa) |
| | LOC101735201 | M20_dimer domain-containing protein. (405 aa) |
| | dock3 | Dedicator of cytokinesis 3. (203 aa) |
| | acy1 | Uncharacterized protein. (211 aa) |
| | farsb | Phenylalanine tRNA synthetase like beta subunit. (588 aa) |
| | hpd-2 | 4-hydroxyphenylpyruvate dioxygenase. (393 aa) |
| | ALDH8A1 | Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa) |
| | asrgl1 | Uncharacterized protein. (330 aa) |
| | hars2 | AA_TRNA_LIGASE_II domain-containing protein. (367 aa) |
| | gatb | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (519 aa) |
| | mmut | Calmodulin regulated spectrin associated protein family member 3. (813 aa) |
| | dlst | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2) (E2K). (453 aa) |
| | NARS2 | Asparaginyl-tRNA synthetase 2, mitochondrial. (608 aa) |
| | LOC100498257 | StAR-related lipid transfer (START) domain containing 15; Belongs to the glutamine synthetase family. (397 aa) |
| | asl | LOC100127798 protein. (464 aa) |
| | MGC75760 | Hcy-binding domain-containing protein. (311 aa) |
| | azin1 | E1A binding protein p400; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (442 aa) |
| | atf4 | Activating transcription factor 4 (Tax-responsive enhancer element B67). (343 aa) |
| | glud1 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (540 aa) |
| | dglucy | Ectonucleotide pyrophosphatase/phosphodiesterase 6. (618 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (185 aa) |
| | mtr | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1269 aa) |
| | adi1 | EARP-interacting protein homolog; Belongs to the WD repeat EIPR1 family. (513 aa) |
| | CARS2 | Probable cysteine--tRNA ligase, mitochondrial. (608 aa) |
| | plod3 | Uncharacterized protein. (585 aa) |
| | CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (1995 aa) |
| | tdo2 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa) |
| | bckdha | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (433 aa) |
| | th2 | Uncharacterized protein. (434 aa) |
| | mars1 | WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (905 aa) |
| | ddah2 | Coiled-coil domain containing 9. (274 aa) |
| | acmsd | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | ICMT | Protein-S-isoprenylcysteine O-methyltransferase. (290 aa) |
| | haao | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (287 aa) |
| | mafg | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (377 aa) |
| | vars | Kinesin family member 18A; Belongs to the class-I aminoacyl-tRNA synthetase family. (1269 aa) |
| | hao1 | FMN hydroxy acid dehydrogenase domain-containing protein. (369 aa) |
| | NOS1 | Nitric oxide synthase; Produces nitric oxide (NO). (1420 aa) |
| | mri1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (354 aa) |
| | shmt2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (514 aa) |
| | ctps1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (602 aa) |
| | aldh6a1 | Toll like receptor 3. (548 aa) |
| | LOC100486129 | Nicotinamide phosphoribosyltransferase. (314 aa) |
| | iars1 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1268 aa) |
| | gls | SPOUT domain containing methyltransferase 1. (588 aa) |
| | aspg | ANK_REP_REGION domain-containing protein. (648 aa) |
| | hibadh | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (368 aa) |
| | sephs1 | Selenide, water dikinase 1; Synthesizes selenophosphate from selenide and ATP. (392 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (761 aa) |
| | LOC101730350 | Peroxiredoxin 2. (425 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (687 aa) |
| | pfas | Glutamine amidotransferase type-1 domain-containing protein. (1351 aa) |
| | LOC100497030 | NIPA-like domain containing 3. (541 aa) |
| | sars2 | AA_TRNA_LIGASE_II domain-containing protein. (513 aa) |
| | tha1p | Beta_elim_lyase domain-containing protein. (409 aa) |
| | ACAD8 | Acyl-CoA dehydrogenase family member 8. (427 aa) |
| | aars1 | Lysine methyltransferase 5B; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. (999 aa) |
| | abat | LOC100158654 protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa) |
| | veph1 | Cleavage stimulation factor, 3' pre-RNA, subunit 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (467 aa) |
| | azin2 | Sodium-dependent phosphate transporter 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (458 aa) |
| | ppat | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (540 aa) |
| | TPH2 | Tryptophan hydroxylase 2. (485 aa) |
| | gad1.2 | Cadherin 22. (581 aa) |
| | shmt1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (485 aa) |
| | aasdh | Receptor associated protein of the synapse. (1084 aa) |
| | yars1 | Tyrosine--tRNA ligase, cytoplasmic; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). (493 aa) |
| | hsd17b10 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (294 aa) |
| | HMGCLL1 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (336 aa) |
| | got1 | Aspartate aminotransferase. (485 aa) |
| | rimklb | ATP-grasp domain-containing protein. (396 aa) |
| | dtl | Denticleless protein homolog; Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2. CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. [...] (750 aa) |
| | bckdk | Protein-serine/threonine kinase. (415 aa) |
| | enoph1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (259 aa) |
| | dusp4-2 | Dual specificity phosphatase 4. (290 aa) |
| | afmid | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (296 aa) |
| | cars1 | Cysteine--tRNA ligase, cytoplasmic. (729 aa) |
| | SMIM36 | Small integral membrane protein 36. (87 aa) |
| | rars1 | Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. (688 aa) |
| | qdpr | Interferon-related developmental regulator 2. (241 aa) |
| | bckdhb | Chymotrypsin like elastase 2A. (398 aa) |
| | GFPT1 | Glutamine--fructose-6-phosphate transaminase 1. (697 aa) |
| | RARS2 | Arginyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (578 aa) |
| | iyd | Iodotyrosine deiodinase. (293 aa) |
| | tat | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (456 aa) |
| | upb1 | LOC100145317 protein. (383 aa) |
| | GPT2 | Alanine aminotransferase 2. (585 aa) |
| | mpst | Sulfurtransferase. (299 aa) |
| | nit2 | Omega-amidase NIT2; Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha- ketoglutarate and oxaloacetate, respectively. (295 aa) |
| | cth | Small integral membrane protein 12. (400 aa) |
| | phgdh | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (509 aa) |
| | rimkla | ATP-grasp domain-containing protein. (381 aa) |
| | MARS2 | Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (571 aa) |
| | aadacl3 | Component of oligomeric golgi complex 6. (413 aa) |
| | LOC101734436 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (396 aa) |
| | prodh2 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (172 aa) |
| | iffo2 | IF rod domain-containing protein; Belongs to the aldehyde dehydrogenase family. (803 aa) |
| | ENSXETP00000034323 | Uncharacterized protein. (292 aa) |
| | lrrc47 | LOC100145802 protein. (570 aa) |
| | Gnmt | Uncharacterized protein. (69 aa) |
| | slc38a7-2 | Insulin-induced gene 2 protein. (137 aa) |
| | srr | LOC100144980 protein. (323 aa) |
| | apip | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. (239 aa) |
| | LOC100497555 | Uncharacterized protein. (381 aa) |
| | DDO | D-aspartate oxidase. (339 aa) |
| | NARS1 | Asparaginyl-tRNA synthetase. (561 aa) |
| | hal.1 | Histidine ammonia-lyase; Belongs to the PAL/histidase family. (669 aa) |
| | amdhd1 | Probable imidazolonepropionase. (432 aa) |
| | cdo1 | Cysteine dioxygenase. (201 aa) |
| | thnsl2 | Keratinocyte associated protein 3. (476 aa) |
| | dao | Telomeric repeat-binding factor 2-interacting protein 1. (368 aa) |
| | hars | Malate synthase, glyoxysomal. (513 aa) |
| | noxred1 | NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase. (344 aa) |
| | psat1 | Transmembrane and coiled-coil domains 3. (392 aa) |
| | ubxn2a-2 | UBX domain protein 2A; Belongs to the class-I aminoacyl-tRNA synthetase family. (161 aa) |
| | aadat | Vitelline membrane outer layer 1 homolog. (433 aa) |
| | acadsb | Uncharacterized protein. (429 aa) |
| | ears2 | Probable glutamate--tRNA ligase, mitochondrial; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (516 aa) |
| | dalrd3 | LIM homeobox 2. (574 aa) |
| | farsa | AA_TRNA_LIGASE_II domain-containing protein. (509 aa) |
| | il4i1 | Amine oxidase. (530 aa) |
| | gcdh | Dolichyldiphosphatase 1. (484 aa) |
| | aasdhppt | Ras and Rab interactor 3. (308 aa) |
| | mthfr | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (676 aa) |
| | LOC108644833 | Exocyst complex component 3-like 2. (623 aa) |
| | gcat | Plakophilin 4. (428 aa) |
| | odc1 | Dymeclin; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (464 aa) |
| | iars2 | NIMA-related kinase 5; Belongs to the class-I aminoacyl-tRNA synthetase family. (1098 aa) |
| | mccc2 | Uncharacterized protein. (566 aa) |
| | fah | Fumarylacetoacetase. (433 aa) |
| | otc | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (351 aa) |
| | QARS1 | Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (772 aa) |
| | kars1 | Lysine--tRNA ligase. (610 aa) |
| | pars2 | LOC100145097 protein. (466 aa) |
| | cps1 | Carbamoyl-phosphate synthase 1. (1462 aa) |
| | hmgcl | Layilin. (363 aa) |
| | gclc | Glutamate-cysteine ligase, catalytic subunit. (637 aa) |
| | DARS2 | Aspartyl-tRNA synthetase 2, mitochondrial. (639 aa) |
| | enosf1 | MR_MLE domain-containing protein. (445 aa) |
| | thap4 | THAP-type domain-containing protein. (502 aa) |
| | sdad1 | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (714 aa) |
| | ftcd | Clock circadian regulator. (560 aa) |
| | kynu | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (480 aa) |
| | etfa | Electron transferring flavoprotein, alpha polypeptide. (333 aa) |
| | dhfr-2 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (189 aa) |
| | LOC100492368 | THAP-type domain-containing protein. (763 aa) |
| | kmo | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (478 aa) |
| | wars1 | WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (517 aa) |
| | dpyd | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1028 aa) |
| | arg1 | Arginase. (333 aa) |
| | agxt | Serine--pyruvate aminotransferase. (416 aa) |
| | vars2 | Elastin microfibril interfacer 3; Belongs to the class-I aminoacyl-tRNA synthetase family. (1080 aa) |
| | dars1 | Cell death inducing DFFA like effector b. (531 aa) |
| | eprs1 | Solute carrier family 12, member 9. (1715 aa) |
| | magi3 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes; Belongs to the MAGUK family. (1595 aa) |
| | gad2 | Peptidoglycan recognition protein 1. (588 aa) |
| | thnsl1 | Solute carrier family 49 member 4 homolog. (783 aa) |
| | blmh | Bleomycin hydrolase; Belongs to the peptidase C1 family. (466 aa) |
| | LOC100497391 | LanC like 3. (582 aa) |
| | AMT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (409 aa) |
| | gclm | Glutamate-cysteine ligase, modifier subunit. (274 aa) |
| | aass | NIN1 (RPN12) binding protein 1 homolog. (964 aa) |
| | kyat3 | Zinc finger and AT-hook domain containing. (453 aa) |
| | pipox | Ataxin 2. (393 aa) |
| | adhfe1 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity); Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily. (544 aa) |
| | GLDC | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1024 aa) |
| | hibch | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity); Belongs to the enoyl-CoA hydratase/isomerase family. (587 aa) |
| | ivd | Uncharacterized protein. (441 aa) |
| | GLS2 | Glutaminase 2. (652 aa) |
| | hdc | R3H domain-containing 2. (680 aa) |
| | ENSXETP00000054447 | Uncharacterized protein. (94 aa) |
| | tars3 | Threonine--tRNA ligase 2, cytoplasmic; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post- transfer stage. (814 aa) |
| | nos2 | Nitric oxide synthase; Produces nitric oxide (NO). (1172 aa) |
| | asns | Asparagine synthetase [glutamine-hydrolyzing]. (561 aa) |
| | nox4 | Short chain dehydrogenase/reductase family 16C member 5. (583 aa) |
| | TH | Tyrosine hydroxylase. (478 aa) |
| | SARDH | Sarcosine dehydrogenase. (906 aa) |
| | pah | 3-hydroxy-3-methylglutaryl-CoA reductase. (450 aa) |
| | hgd | CCAAT enhancer binding protein beta. (458 aa) |
| | prodh | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (629 aa) |
| | sdsl | PALP domain-containing protein. (332 aa) |
| | sds | DEAH-box helicase 15. (328 aa) |
| | glul | Glutamine synthetase. (371 aa) |
| | LOC100487738 | Protocadherin alpha subfamily C, 2. (765 aa) |
| | LOC101731157 | Aminotran_1_2 domain-containing protein. (621 aa) |
| | ddc | Uncharacterized protein. (488 aa) |
| | asnsd1 | Glutamine amidotransferase type-2 domain-containing protein. (610 aa) |
| | gars1 | Transmembrane protein 37. (745 aa) |
| | yars2 | Tyrosine--tRNA ligase. (464 aa) |
| | got2 | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. May facilitate cellular uptake of long-chain free fatty acids (By similarity). (427 aa) |
| | LOC100493420 | UDP glucuronosyltransferase 1 family, polypeptide A6. (742 aa) |
| | aldh5a1 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (526 aa) |
| | slc25a44 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (332 aa) |
| | arg2 | Arginase. (360 aa) |
| | bcat2 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (418 aa) |
| | hpd | 4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine; Belongs to the 4HPPD family. (396 aa) |
| | LOC100498594 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (454 aa) |
| | hpdl | 4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family. (398 aa) |
| | entpd7 | Ectonucleoside triphosphate diphosphohydrolase 7; Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP (By similarity). (617 aa) |
| | tars1 | AA_TRNA_LIGASE_II domain-containing protein. (724 aa) |
| | NAGS | N-acetylglutamate synthase. (496 aa) |
| | etfb | Pyruvate dehydrogenase E1 beta subunit. (302 aa) |
| | pm20d1 | N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration. (513 aa) |
| | fpgs | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (589 aa) |
| | gpt | Alanine aminotransferase 2; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. (784 aa) |
| | sars1 | SMAD specific E3 ubiquitin protein ligase 1. (559 aa) |
| | ddah1 | LOC100145661 protein. (284 aa) |
| | PYCR3 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (274 aa) |
| | nos3 | Nitric oxide synthase; Produces nitric oxide (NO). (1113 aa) |
| | sirt4 | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (322 aa) |
| | ankrd49 | THAP-type domain-containing protein. (776 aa) |
| | lars2 | Bone morphogenetic protein 8 (osteogenic protein 2); Belongs to the class-I aminoacyl-tRNA synthetase family. (914 aa) |
| | rbfox2 | RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons (By similarity). (444 aa) |
| | dbt | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (540 aa) |
| | tst | Uncharacterized protein. (294 aa) |
| | glul-2 | Glutamine synthetase. (373 aa) |
| | GMPS | Guanine monophosphate synthase. (763 aa) |
| | bhmt | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). (438 aa) |
| | agxt2 | Recoverin, gene 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (508 aa) |
| | ENSXETP00000011115 | THAP-type domain-containing protein. (768 aa) |
| | mtfp1-2 | Mitochondrial fission process 1. (321 aa) |
| | LOC100496394 | Amine oxidase. (510 aa) |
| | ola1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. (401 aa) |
| | LOC101734368 | RNA pseudouridylate synthase domain containing 2. (107 aa) |
