STRINGSTRING
adk adk hprt1 hprt1 prtfdc1 prtfdc1 dpyd dpyd LOC734042 LOC734042 ENSXETP00000047005 ENSXETP00000047005 NT5C1A NT5C1A dtymk dtymk tymp tymp cdadc1 cdadc1 LOC100145149 LOC100145149 fgl1l fgl1l zp3.2-2 zp3.2-2 upp2 upp2 Gnmt Gnmt gda gda LOC548390 LOC548390 upb1 upb1 aprt aprt rbl1-3 rbl1-3 tk1 tk1 apobec2 apobec2 pnp pnp NT5E NT5E prxl2a-2 prxl2a-2 ENSXETP00000025727 ENSXETP00000025727 ICMT ICMT DGUOK DGUOK ADA2 ADA2 upp1 upp1 ENSXETP00000004830 ENSXETP00000004830 nudt1 nudt1 acpp acpp nt5c1a nt5c1a ada ada ada.2 ada.2 LOC100145000 LOC100145000 mtap mtap Cda Cda irf3-2 irf3-2 stac stac nt5c2 nt5c2 adal adal nt5dc4 nt5dc4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adkTransmembrane phosphoinositide 3-phosphatase and tensin homolog 2. (370 aa)
hprt1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (224 aa)
prtfdc1Phosphoribosyltransferase domain-containing protein 1; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (224 aa)
dpydDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1028 aa)
LOC734042IU_nuc_hydro domain-containing protein. (319 aa)
ENSXETP00000047005Uncharacterized protein. (222 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (364 aa)
dtymkDeoxythymidylate kinase (Thymidylate kinase). (216 aa)
tympThymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (513 aa)
cdadc1Solute carrier family 35 member F1. (471 aa)
LOC100145149Fatty acid binding protein 3. (245 aa)
fgl1lFibrinogen C-terminal domain-containing protein. (279 aa)
zp3.2-2Serine/arginine-rich splicing factor 4. (153 aa)
upp2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (316 aa)
GnmtUncharacterized protein. (69 aa)
gdaGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (478 aa)
LOC548390LOC548390 protein. (322 aa)
upb1LOC100145317 protein. (383 aa)
aprtAdenine phosphoribosyltransferase. (180 aa)
rbl1-3Retinoblastoma-like 1. (235 aa)
tk1Thymidine kinase. (262 aa)
apobec2Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2. (234 aa)
pnpPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (297 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (582 aa)
prxl2a-2Peroxiredoxin-like 2A. (266 aa)
ENSXETP00000025727Macro domain-containing protein. (112 aa)
ICMTProtein-S-isoprenylcysteine O-methyltransferase. (290 aa)
DGUOKDeoxyguanosine kinase. (265 aa)
ADA2Adenosine deaminase 2. (424 aa)
upp1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (311 aa)
ENSXETP00000004830Uncharacterized protein. (118 aa)
nudt1Leucine rich repeat and fibronectin type III domain containing 3; Belongs to the Nudix hydrolase family. (156 aa)
acppTransmembrane protein 205; Belongs to the histidine acid phosphatase family. (419 aa)
nt5c1aUncharacterized protein. (430 aa)
adaAdenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (359 aa)
ada.2A_deaminase domain-containing protein. (415 aa)
LOC100145000ELF1 homolog, elongation factor 1. (322 aa)
mtapS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (282 aa)
CdaCytidine deaminase. (118 aa)
irf3-2Interferon regulatory factor 3. (223 aa)
stacSH3 and cysteine rich domain. (220 aa)
nt5c2Cytosolic purine 5'-nucleotidase; May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides (By similarity). (638 aa)
adalA_deaminase domain-containing protein. (360 aa)
nt5dc4TELO2 interacting protein 1. (535 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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