STRINGSTRING
chmp6 chmp6 shisa9 shisa9 crh crh LOC100485454 LOC100485454 grem1 grem1 dkk3 dkk3 dlgap3 dlgap3 reln reln prrt1 prrt1 WFIKKN2 WFIKKN2 adra2c adra2c PCSK9 PCSK9 socs5 socs5 nptx2 nptx2 SHANK3 SHANK3 dlgap2 dlgap2 adam17 adam17 lrpap1 lrpap1 fst fst rasgrf1 rasgrf1 cblc cblc NCAPG2 NCAPG2 SHANK1 SHANK1 ADRA2B ADRA2B SERPINE1 SERPINE1 rasgrf2 rasgrf2 errfi1 errfi1 fes fes LOC108644804 LOC108644804 LOC101734025 LOC101734025 ENSXETP00000033698 ENSXETP00000033698 ENSXETP00000033645 ENSXETP00000033645 tm4sf4-2 tm4sf4-2 LYPD1 LYPD1 bud31 bud31 areg areg ereg ereg epgn epgn sult2b1-2 sult2b1-2 fbxw9 fbxw9 dkk1 dkk1 CGA CGA klhl24 klhl24 LOC100495217 LOC100495217 rwdd1 rwdd1 tsg101 tsg101 tgfa tgfa fam72a fam72a app app ifngr2.1 ifngr2.1 neurl1 neurl1 FSHB FSHB dkk2 dkk2 rhebl1-2 rhebl1-2 cacng7 cacng7 il10 il10 cacng8 cacng8 CNIH3 CNIH3 ttpal-2 ttpal-2 tnf tnf KLHL35 KLHL35 edn1 edn1 nap1l4 nap1l4 NETO1 NETO1 ifngr2.2 ifngr2.2 mtbp mtbp TAFA4 TAFA4 cnrip1 cnrip1 shisa8 shisa8 HBEGF HBEGF gprc5a gprc5a crhbp crhbp neto2 neto2 cacng2 cacng2 SHISA7 SHISA7 homer3 homer3 ncf1 ncf1 vps25 vps25 LOC108644813 LOC108644813 umod.3 umod.3 LOC100485319 LOC100485319 cblb cblb nptxr nptxr dlgap1 dlgap1 ppara ppara fbxw7 fbxw7 dlgap4 dlgap4 ramp3 ramp3 cnih2 cnih2 socs4 socs4 OPRM1 OPRM1 nsun2 nsun2 cbl cbl zfyve28 zfyve28 psen1 psen1 lypd6 lypd6 LYPD6B LYPD6B wfikkn1 wfikkn1 cacng3 cacng3 LOC101734139 LOC101734139 bhlhe40-2 bhlhe40-2 LOC100158595 LOC100158595 elovl5-2 elovl5-2 gga1-2 gga1-2 homer1 homer1 LOC100493455 LOC100493455 BTC BTC ARC ARC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chmp6LOC100125185 protein. (200 aa)
shisa9Protein shisa-9; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity). (390 aa)
crhCRF domain-containing protein. (207 aa)
LOC100485454CRF domain-containing protein. (226 aa)
grem1Gremlin. (182 aa)
dkk3Ankyrin repeat and SOCS box containing 4. (336 aa)
dlgap3Uncharacterized protein. (999 aa)
relnG protein-coupled receptor 119. (3463 aa)
prrt1Sushi domain containing 2. (240 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (559 aa)
adra2cLOC100145449 protein. (433 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (684 aa)
socs5Suppressor of cytokine signaling 5. (535 aa)
nptx2Nptx2 protein. (439 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1850 aa)
dlgap2Vacuolar protein sorting 4 homolog A. (973 aa)
adam17Monooxygenase, DBH-like 2, pseudogene. (834 aa)
lrpap1PC-esterase domain containing 1A. (371 aa)
fstChloride channel, voltage-sensitive 6. (343 aa)
rasgrf1DNA topoisomerase I, gene 2. (1240 aa)
cblcUncharacterized protein. (425 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1152 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (1900 aa)
ADRA2BAdrenoceptor alpha 2B. (415 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (449 aa)
rasgrf2CTD small phosphatase 1. (1232 aa)
errfi1CD53 molecule. (404 aa)
fesVoltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (305 aa)
LOC108644804WD_REPEATS_REGION domain-containing protein. (313 aa)
LOC101734025DEAD-box helicase 3 Y-linked. (462 aa)
ENSXETP00000033698Uncharacterized protein. (613 aa)
ENSXETP00000033645WD_REPEATS_REGION domain-containing protein. (374 aa)
tm4sf4-2Transmembrane 4 L six family member 4. (375 aa)
LYPD1LY6/PLAUR domain containing 1. (86 aa)
bud31C77604 protein. (144 aa)
aregEGF-like domain-containing protein. (226 aa)
eregNIMA-related kinase 6. (156 aa)
epgnLeucine-rich repeats and calponin homology (CH) domain containing 1. (138 aa)
sult2b1-2Sec1 family domain containing 2. (113 aa)
fbxw9Exocyst complex component 5. (438 aa)
dkk1Dickkopf 1. (257 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (122 aa)
klhl24DRE1 protein. (600 aa)
LOC100495217UTP14A, small subunit processome component. (263 aa)
rwdd1RWD domain containing 1. (239 aa)
tsg101Thrombospondin 2. (239 aa)
tgfaSolute carrier family 6 (neurotransmitter transporter), member 8 like. (163 aa)
fam72aSpermatogenesis associated 1. (151 aa)
appGeneral transcription factor IIE subunit 2. (769 aa)
ifngr2.1Uncharacterized protein. (311 aa)
neurl1Neurl protein. (555 aa)
FSHBFollicle stimulating hormone subunit beta. (134 aa)
dkk2Dickkopf_N domain-containing protein. (156 aa)
rhebl1-2Uncharacterized protein. (152 aa)
cacng7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
il10Activating transcription factor 6. (172 aa)
cacng8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (353 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (152 aa)
ttpal-2Tocopherol (alpha) transfer protein-like. (48 aa)
tnfThyrotropin-releasing hormone receptor 3. (227 aa)
KLHL35Kelch like family member 35. (574 aa)
edn1Nidogen 2. (222 aa)
nap1l4Nucleosome assembly protein 1like 4. (321 aa)
NETO1Neuropilin and tolloid like 1. (529 aa)
ifngr2.2Lactamase beta. (337 aa)
mtbpMdm2-binding protein; May play a role in mdm2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of mdm2, thereby enhancing mdm2 stability. This promotes mdm2-mediated ubiquitination of p53/TP53 and its subsequent degradation (By similarity). (867 aa)
TAFA4TAFA chemokine like family member 4. (221 aa)
cnrip1LOC100145710 protein. (162 aa)
shisa8Ring finger protein 216. (381 aa)
HBEGFHeparin binding EGF like growth factor. (195 aa)
gprc5aG_PROTEIN_RECEP_F3_4 domain-containing protein. (362 aa)
crhbpCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (321 aa)
neto2Uncharacterized protein. (525 aa)
cacng2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
SHISA7Shisa family member 7. (504 aa)
homer3Rh-associated glycoprotein. (359 aa)
ncf1Ncf1 protein. (391 aa)
vps25Sialic acid binding Ig-like lectin 10. (174 aa)
LOC108644813Uncharacterized protein. (300 aa)
umod.3Uromodulin (uromucoid, Tamm-Horsfall glycoprotein), gene 3. (1099 aa)
LOC100485319Crystallin mu. (843 aa)
cblbE3 ubiquitin-protein ligase CBL-B; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. (982 aa)
nptxrTrafficking protein particle complex 5. (479 aa)
dlgap1UTP18 small subunit processome component. (980 aa)
pparaLysosomal-associated membrane protein 1. (474 aa)
fbxw7Uncharacterized protein. (773 aa)
dlgap4Mitogen-activated protein kinase kinase kinase 8. (1071 aa)
ramp3Uncharacterized protein. (147 aa)
cnih2Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs); Belongs to the cornichon family. (162 aa)
socs4Fibroblast growth factor binding protein 2. (436 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (388 aa)
nsun2RNA cytosine-C(5)-methyltransferase NSUN2; RNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs). Involved in various processes, such as epidermal stem cell differentiation, testis differentiation and maternal to zygotic transition during early development: acts by increasing protein synthesis; cytosine C(5)-methylation promoting tRNA stability and preventing mRNA decay. Methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) p [...] (798 aa)
cblUncharacterized protein. (954 aa)
zfyve28Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. (954 aa)
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
lypd6Sel-1 suppressor of lin-12-like 3. (171 aa)
LYPD6BLY6/PLAUR domain containing 6B. (171 aa)
wfikkn1Carbohydrate (keratan sulfate Gal-6) sulfotransferase 1. (545 aa)
cacng3EH domain containing 4. (317 aa)
LOC101734139HYDIN, axonemal central pair apparatus protein. (467 aa)
bhlhe40-2Protein zwilch homolog. (436 aa)
LOC100158595High choriolytic enzyme 2. (427 aa)
elovl5-2Elongation of very long chain fatty acids protein 5. (431 aa)
gga1-2Golgi-associated, gamma adaptin ear containing, ARF binding protein 1. (202 aa)
homer1Prolactin-releasing peptide receptor-like. (394 aa)
LOC100493455RBPJ interacting and tubulin associated 1. (580 aa)
BTCBetacellulin. (170 aa)
ARCActivity regulated cytoskeleton associated protein. (369 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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