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| | wdr60 | WD repeat domain 60. (1116 aa) |
| | borcs5 | BLOC-1-related complex subunit 5; As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. Belongs to the BORCS5 family. (196 aa) |
| | ift140 | Uncharacterized protein. (1461 aa) |
| | IFT88 | Intraflagellar transport 88. (826 aa) |
| | rhot2 | Mitochondrial Rho GTPase 2; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity). (629 aa) |
| | terf2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (471 aa) |
| | TTC21A | Tetratricopeptide repeat domain 21A. (1312 aa) |
| | SUN2 | SUN domain-containing protein. (707 aa) |
| | copg1 | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (874 aa) |
| | cep131 | Prostaglandin E receptor 2. (1095 aa) |
| | kif5a | Zinc finger protein 451; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1033 aa) |
| | gadl1 | Acidic amino acid decarboxylase GADL1; Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L- alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is L- aspartate. Does not exhibit any decarboxylation activity toward glutamate. (522 aa) |
| | ift46 | Taste 2 receptor member 7. (419 aa) |
| | dync2li1 | Uncharacterized protein. (341 aa) |
| | kif1c | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1105 aa) |
| | ift52 | Achaete-scute family bHLH transcription factor 2. (452 aa) |
| | bloc1s1 | Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. May also play a role in intracellular vesicle trafficking. As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BLOC1S1 family. (125 aa) |
| | bicdl1 | BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth; Belongs to the BICDR family. (603 aa) |
| | sybu | FAD-dependent oxidoreductase domain containing 2. (653 aa) |
| | ift43 | Intraflagellar transport protein 43 homolog; As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is involved in ciliogenesis. Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base. (201 aa) |
| | mgarp | AIF-MLS domain-containing protein. (560 aa) |
| | ap3d1 | AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (1125 aa) |
| | BBS12 | Bardet-Biedl syndrome 12. (676 aa) |
| | pex14 | Pseudopodium-enriched atypical kinase 1. (362 aa) |
| | ssna1 | Uncharacterized protein. (116 aa) |
| | bloc1s2 | Biogenesis of lysosome-related organelles complex 1 subunit 2; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. May also play a role in intracellular vesicle trafficking. As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. (147 aa) |
| | atg4d-2 | Autophagy related 4D, cysteine peptidase. (561 aa) |
| | LOC100497171 | Lebercilin domain-containing protein. (590 aa) |
| | ttc30a | Tetratricopeptide repeat protein 30A; Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip; Belongs to the TTC30/dfy-1/fleer family. (651 aa) |
| | ctdspl2-2 | CTD small phosphatase-like protein 2. (251 aa) |
| | plin1-2 | Pepdidase_M14_N domain-containing protein. (162 aa) |
| | stau1 | Uncharacterized protein. (721 aa) |
| | dync1i1 | Dync1i1 protein. (627 aa) |
| | hap1 | Uncharacterized protein. (938 aa) |
| | spag17 | Myostatin, gene 1. (2137 aa) |
| | wdr19-2 | Cyclin-dependent kinase 8. (1298 aa) |
| | spg7 | Tetraspanin 31. (768 aa) |
| | BICD1 | BICD cargo adaptor 1. (702 aa) |
| | borcs7 | BLOC-1-related complex subunit 7; As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. Belongs to the BORCS7 family. (112 aa) |
| | kcnq4-2 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (983 aa) |
| | wdr19 | Uncharacterized protein. (837 aa) |
| | ap3b2 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1106 aa) |
| | mak | DnaJ heat shock protein family (Hsp40) member C3. (658 aa) |
| | LOC100498570 | Uncharacterized protein. (312 aa) |
| | KIF1B | Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1793 aa) |
| | PCM1 | Pericentriolar material 1. (2051 aa) |
| | spg11 | Lymphocyte specific protein 1. (1876 aa) |
| | dpysl3 | Dihydropyrimidinase-related protein 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity). (673 aa) |
| | pafah1b1 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (414 aa) |
| | ift81 | Transportin 1. (674 aa) |
| | bcas4 | Uncharacterized protein. (459 aa) |
| | ift74 | Intraflagellar transport 74 homolog. (601 aa) |
| | cln3 | Uncharacterized protein. (579 aa) |
| | kif5c | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (959 aa) |
| | kif5b | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (962 aa) |
| | TRAK1 | Uncharacterized protein. (1002 aa) |
| | bicd2l | Uncharacterized protein. (764 aa) |
| | hspb11 | Novel protein similar to c1orf41. (139 aa) |
| | SUN1 | Sad1 and UNC84 domain containing 1. (943 aa) |
| | ap3m2 | AP-3 complex subunit mu-2. (418 aa) |
| | ICK | Intestinal cell kinase. (623 aa) |
| | DYNC2H1 | Dynein cytoplasmic 2 heavy chain 1. (4246 aa) |
| | wdr34 | RWD domain containing 2B. (503 aa) |
| | bloc1s3 | Uncharacterized protein. (188 aa) |
| | arl8b | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (186 aa) |
| | actr10 | Uncharacterized protein; Belongs to the actin family. (421 aa) |
| | thumpd2-2 | THUMP domain containing 2. (4637 aa) |
| | kif1a | Nitric oxide synthase 1 adaptor protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1795 aa) |
| | ift122 | Intraflagellar transport protein 122 homolog; Required for cilia formation during embryonal development. Acts as a negative regulator of Shh signaling. (1222 aa) |
| | TTC21B | Tetratricopeptide repeat domain 21B. (1334 aa) |
| | dtnbp1 | Nuclear receptor coactivator 1. (355 aa) |
| | traf3ip1 | Uncharacterized protein. (628 aa) |
| | arl10b | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (205 aa) |
| | nde1 | Nuclear distribution protein nudE homolog 1; Required for centrosome duplication and formation and function of the mitotic spindle; Belongs to the nudE family. (340 aa) |
| | bloc1s6 | Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (173 aa) |
| | stau2 | Double-stranded RNA-binding protein Staufen homolog 2; RNA-binding protein required for the microtubule-dependent transport of RNAs within polarized cell types. (726 aa) |
| | ift20 | Intraflagellar transport protein 20 homolog; Involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella. (132 aa) |
| | copg2 | Coatomer subunit gamma-2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). (883 aa) |
| | htt | Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). (3110 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1097 aa) |
| | bicdl2 | BICD family-like cargo adapter 2; Belongs to the BICDR family. (493 aa) |
| | tctex1d2 | Lysophosphatidic acid receptor 6-like. (124 aa) |
| | ttc26 | Intraflagellar transport protein 56; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Essential for maintaining proper microtubule organization within the ciliary axoneme. (554 aa) |
| | ift27 | Uncharacterized protein. (210 aa) |
| | spast | Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (603 aa) |
| | arl8a | ADP-ribosylation factor-like protein 8A; May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation (By similarity); Belongs to the small GTPase superfamily. Arf family. (186 aa) |
| | cnppd1-2 | Caspase 2. (84 aa) |
| | cfap70 | Protein kinase, AMP-activated, alpha 1 catalytic subunit. (1000 aa) |
| | SSX2IP | SSX family member 2 interacting protein. (552 aa) |
| | WDR35 | WD repeat-containing protein 35. (1181 aa) |
| | borcs8 | Uncharacterized protein. (118 aa) |
| | clip3 | ANTXR cell adhesion molecule 1. (534 aa) |
| | TBRG4 | FAST kinase domain-containing protein 4; Plays a role in processing of mitochondrial RNA precursors and in stabilization of a subset of mature mitochondrial RNA species. May play a role in cell cycle progression. Belongs to the FAST kinase family. (449 aa) |
| | trak2 | Putative oxidoreductase GLYR1. (906 aa) |
| | app | General transcription factor IIE subunit 2. (769 aa) |
| | hspb1 | Zinc finger MYM-type containing 4; Belongs to the small heat shock protein (HSP20) family. (211 aa) |
| | ndel1 | Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. (345 aa) |
| | bloc1s4 | Cappuccino homolog (Mouse). (215 aa) |
| | dync1i2 | Cysteine-serine-rich nuclear protein 2. (644 aa) |
| | ENSXETP00000025007 | Uncharacterized protein. (63 aa) |
| | RHOT1 | Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (659 aa) |
| | LOC100036665 | Uncharacterized protein. (730 aa) |
