STRINGSTRING
rnf10 rnf10 eef2k eef2k ganc-2 ganc-2 lrfn4 lrfn4 ADCY1 ADCY1 shank2 shank2 pak3 pak3 GRM5 GRM5 iqsec3 iqsec3 kpna1 kpna1 grin3a grin3a dlg2 dlg2 slc6a14.2-2 slc6a14.2-2 grin2d grin2d drosha drosha ptpro ptpro add2 add2 NETO1 NETO1 LOC100488567 LOC100488567 rnf112.1 rnf112.1 dlg3 dlg3 PPP1R9A PPP1R9A tra2b-2 tra2b-2 shisa8 shisa8 sytl4 sytl4 neto2 neto2 cacng2 cacng2 SHISA7 SHISA7 homer3 homer3 ppp1r9al ppp1r9al GRIN2B GRIN2B IL1RAPL1 IL1RAPL1 LOC108644813 LOC108644813 grip1 grip1 dgkb-2 dgkb-2 cpeb3 cpeb3 homer1 homer1 drp2 drp2 ctnnd2 ctnnd2 cacng3 cacng3 gap43 gap43 abhd17b abhd17b syn2 syn2 PRR12 PRR12 gng3 gng3 LZTS3 LZTS3 tor3a-2 tor3a-2 p2rx4 p2rx4 dlg1 dlg1 pak1 pak1 add3 add3 tsc2 tsc2 Prrt2 Prrt2 sorcs2 sorcs2 fmr1 fmr1 nsun2 nsun2 sos1 sos1 add1 add1 p2rx6 p2rx6 lzts1 lzts1 BAALC BAALC pak2 pak2 efnb2 efnb2 dlgap1 dlgap1 clstn3 clstn3 gria2 gria2 CLSTN2 CLSTN2 dclk1 dclk1 nck2 nck2 lrfn2 lrfn2 lin7b lin7b cpeb1 cpeb1 ENSXETP00000023590 ENSXETP00000023590 cacng8 cacng8 cacng7 cacng7 adgrl1 adgrl1 lin7c lin7c LRFN1 LRFN1 ENSXETP00000025477 ENSXETP00000025477 adam10 adam10 neurl1 neurl1 ppp1r9b ppp1r9b ENSXETP00000027334 ENSXETP00000027334 baiap2 baiap2 CLSTN1 CLSTN1 dmtn dmtn tsc1 tsc1 rarb rarb rpl27-2 rpl27-2 cnppd1-2 cnppd1-2 crtc1 crtc1 slitrk1 slitrk1 GRIP2 GRIP2 npl npl gphn gphn rps3 rps3 igsf11 igsf11 fxr1 fxr1 nsmf nsmf grasp grasp dbn1 dbn1 adam22 adam22 PRR7 PRR7 Syt11 Syt11 fes fes ncs1 ncs1 dagla dagla SHANK1 SHANK1 abhd17a abhd17a lrfn3 lrfn3 gria1 gria1 PALM PALM ENSXETP00000038077 ENSXETP00000038077 dgcr8 dgcr8 GRID2 GRID2 CPEB4 CPEB4 GRIN3B GRIN3B synj2bp synj2bp pick1-2 pick1-2 TNIK TNIK dlgap2 dlgap2 SHANK3 SHANK3 pdlim5 pdlim5 bcl11a bcl11a lyn lyn pja2 pja2 lin7a lin7a cript cript GRIN2C GRIN2C arhgef9 arhgef9 ctnnb1 ctnnb1 il1rapl2 il1rapl2 syn3 syn3 gper1 gper1 RGS7BP RGS7BP mink1 mink1 arhgap32 arhgap32 inpp4a inpp4a ntrk2 ntrk2 prrt1 prrt1 dnajc6 dnajc6 abi1 abi1 GRM1 GRM1 LRRTM3 LRRTM3 dlgap3 dlgap3 abhd17c abhd17c cnksr2 cnksr2 DLG5 DLG5 wnk3 wnk3 dbnl dbnl LRFN5 LRFN5 mib1 mib1 srcin1 srcin1 BMPR2 BMPR2 dtnbp1 dtnbp1 gdf5-2 gdf5-2 ALS2 ALS2 PCLO PCLO shisa9 shisa9 nptn nptn insyn1 insyn1 GRIN2A GRIN2A TANC1 TANC1 pkp4 pkp4 USP8 USP8 homer2 homer2 INSYN2A INSYN2A ARC ARC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rnf10EGF like domain multiple 7. (754 aa)
eef2kNeuraminidase 4 (sialidase). (777 aa)
ganc-2Uncharacterized protein. (78 aa)
lrfn4Uncharacterized protein. (722 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
shank2Uncharacterized protein. (1829 aa)
pak3Non-specific serine/threonine protein kinase. (564 aa)
GRM5Glutamate metabotropic receptor 5. (1172 aa)
iqsec3SEC7 domain-containing protein. (1109 aa)
kpna1Importin subunit alpha; Belongs to the importin alpha family. (563 aa)
grin3aNucleoporin 155kDa; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1124 aa)
dlg2Hemojuvelin BMP co-receptor. (913 aa)
slc6a14.2-2Solute carrier family 6 member 14, gene 2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (622 aa)
grin2dShort chain dehydrogenase/reductase family 42E, member 1. (1274 aa)
droshaKruppel-like factor 8. (1382 aa)
ptproORMDL sphingolipid biosynthesis regulator 1. (1018 aa)
add2Aldolase_II domain-containing protein. (725 aa)
NETO1Neuropilin and tolloid like 1. (529 aa)
LOC100488567ADAM metallopeptidase with thrombospondin type 1 motif 10. (1027 aa)
rnf112.1Vesicle associated membrane protein 2. (628 aa)
dlg3Hyaluronan-mediated motility receptor (RHAMM); Belongs to the MAGUK family. (851 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1156 aa)
tra2b-2Transformer 2 beta homolog. (207 aa)
shisa8Ring finger protein 216. (381 aa)
sytl4Synaptotagmin like 4. (246 aa)
neto2Uncharacterized protein. (525 aa)
cacng2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
SHISA7Shisa family member 7. (504 aa)
homer3Rh-associated glycoprotein. (359 aa)
ppp1r9alUncharacterized protein. (1337 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1449 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (686 aa)
LOC108644813Uncharacterized protein. (300 aa)
grip1Nuclear respiratory factor 1. (1130 aa)
dgkb-2Uncharacterized protein. (90 aa)
cpeb3Cytoplasmic polyadenylation element-binding protein 3; Sequence-specific RNA-binding protein which acts as a translational repressor in the basal unstimulated state but, following neuronal stimulation, acts as a translational activator (By similarity). Does not bind to the cytoplasmic polyadenylation element (CPE), a uridine-rich sequence element within the mRNA 3'-UTR, but binds to a U-rich loop within a stem-loop structure (By similarity). Required for the consolidation and maintenance of hippocampal-based long term memory (By similarity). Inhibits differentiation of intermediate mes [...] (603 aa)
homer1Prolactin-releasing peptide receptor-like. (394 aa)
drp2Chromosome 2 open reading frame 73. (944 aa)
ctnnd2Transcription factor E2F7. (1229 aa)
cacng3EH domain containing 4. (317 aa)
gap43Uncharacterized protein. (210 aa)
abhd17bAlpha/beta hydrolase domain-containing protein 17B; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins; Belongs to the AB hydrolase superfamily. ABHD17 family. (288 aa)
syn2Oxysterol binding protein like 1A. (877 aa)
PRR12Proline rich 12. (2424 aa)
gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LZTS3Leucine zipper tumor suppressor family member 3. (654 aa)
tor3a-2Torsin family 3, member A. (249 aa)
p2rx4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)
dlg1Disks large homolog 1; Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction and cell proliferation (By similarity). (927 aa)
pak1Non-specific serine/threonine protein kinase. (521 aa)
add3ATR serine/threonine kinase. (565 aa)
tsc2Mannosidase, alpha, class 1B, member 1. (1798 aa)
Prrt2Membrane associated ring-CH-type finger 4. (74 aa)
sorcs2Guanylate binding protein 4. (1090 aa)
fmr1Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C). ECO:0000250|UniProtKB:P51113, ECO:0000250|UniProtKB:Q06787. (590 aa)
nsun2RNA cytosine-C(5)-methyltransferase NSUN2; RNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs). Involved in various processes, such as epidermal stem cell differentiation, testis differentiation and maternal to zygotic transition during early development: acts by increasing protein synthesis; cytosine C(5)-methylation promoting tRNA stability and preventing mRNA decay. Methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) p [...] (798 aa)
sos1Organic solute transporter subunit alpha. (1329 aa)
add1Aldolase_II domain-containing protein. (823 aa)
p2rx6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (390 aa)
lzts1Lzts1 protein. (499 aa)
BAALCBAALC binder of MAP3K1 and KLF4. (155 aa)
pak2Non-specific serine/threonine protein kinase. (518 aa)
efnb2Solute carrier family 41 member 2; Belongs to the ephrin family. (329 aa)
dlgap1UTP18 small subunit processome component. (980 aa)
clstn3Glycogen synthase kinase 3 alpha. (965 aa)
gria2DGCR8 microprocessor complex subunit. (900 aa)
CLSTN2Calsyntenin 2. (921 aa)
dclk1Rho GTPase activating protein 24. (753 aa)
nck2Cytoplasmic protein. (381 aa)
lrfn2RRN3 homolog, RNA polymerase I transcription factor. (765 aa)
lin7bProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
cpeb1Uncharacterized protein. (564 aa)
ENSXETP00000023590Uncharacterized protein. (89 aa)
cacng8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (353 aa)
cacng7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
adgrl1DEAH-box helicase 36; Belongs to the G-protein coupled receptor 2 family. (1452 aa)
lin7cProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (742 aa)
ENSXETP00000025477PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (418 aa)
adam10DnaJ heat shock protein family (Hsp40) member C24. (760 aa)
neurl1Neurl protein. (555 aa)
ppp1r9bFrizzled related protein 2. (791 aa)
ENSXETP00000027334Uncharacterized protein. (600 aa)
baiap2Uncharacterized protein. (554 aa)
CLSTN1Calsyntenin 1. (988 aa)
dmtnHP domain-containing protein. (416 aa)
tsc1Distal-less homeobox 1. (1139 aa)
rarbRetinoic acid receptor beta. (52 aa)
rpl27-2Mitofusin 1. (725 aa)
cnppd1-2Caspase 2. (84 aa)
crtc1Josephin domain containing 1. (623 aa)
slitrk1LOC100124997 protein. (696 aa)
GRIP2Glutamate receptor interacting protein 2. (1122 aa)
nplN-acetylneuraminate lyase; Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway (By similarity). (305 aa)
gphnGlucocorticoid modulatory element binding protein 2. (970 aa)
rps3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (246 aa)
igsf11GTP binding protein 2. (360 aa)
fxr1Fragile X mental retardation syndrome-related protein 1 homolog; RNA-binding protein. Binds poly(G) and poly(U) but not poly(A) or poly(C). Regulates somite formation, probably by regulating gene expression (By similarity). (674 aa)
nsmfProtein KIBRA. (503 aa)
graspPDZ domain-containing protein. (352 aa)
dbn1ADF-H domain-containing protein. (665 aa)
adam22Uncharacterized protein. (918 aa)
PRR7Proline rich 7, synaptic. (260 aa)
Syt11Synaptotagmin 11. (295 aa)
fesVoltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (305 aa)
ncs1Frequenin homolog (Drosophila). (190 aa)
daglaCXXC-type zinc finger protein 4. (1032 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (1900 aa)
abhd17aHypothetical LOC496639. (305 aa)
lrfn3Ornithine decarboxylase antizyme 1. (660 aa)
gria1TRAF3 interacting protein 2. (903 aa)
PALMParalemmin. (369 aa)
ENSXETP00000038077Zf-piccolo domain-containing protein. (529 aa)
dgcr8DiGeorge syndrome critical region 8. (772 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1009 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (728 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1035 aa)
synj2bpSynj2bp protein. (145 aa)
pick1-2Uncharacterized protein. (421 aa)
TNIKTRAF2 and NCK interacting kinase. (1281 aa)
dlgap2Vacuolar protein sorting 4 homolog A. (973 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1850 aa)
pdlim5PDZ and LIM domain 5 transcript variant. (583 aa)
bcl11aUncharacterized protein. (794 aa)
lynTyrosine-protein kinase. (524 aa)
pja2F-box protein 30. (779 aa)
lin7aUncharacterized protein. (287 aa)
criptUncharacterized protein. (102 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1189 aa)
arhgef9Peroxiredoxin 4. (824 aa)
ctnnb1Dynactin subunit 5. (788 aa)
il1rapl2Interleukin 1 receptor accessory protein-like 2. (686 aa)
syn3Uncharacterized protein. (570 aa)
gper1Tripartite motif containing 55; Belongs to the G-protein coupled receptor 1 family. (361 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (271 aa)
mink1NME/NM23 family member 9. (1233 aa)
arhgap32Kinase insert domain receptor. (1953 aa)
inpp4aUncharacterized protein. (972 aa)
ntrk2Tyrosine-protein kinase receptor. (821 aa)
prrt1Sushi domain containing 2. (240 aa)
dnajc6Uncharacterized protein. (946 aa)
abi1Uncharacterized protein. (502 aa)
GRM1Glutamate metabotropic receptor 1. (1158 aa)
LRRTM3Leucine rich repeat transmembrane neuronal 3. (514 aa)
dlgap3Uncharacterized protein. (999 aa)
abhd17cAlpha/beta hydrolase domain-containing protein 17C; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins; Belongs to the AB hydrolase superfamily. ABHD17 family. (310 aa)
cnksr2Mitochondrial E3 ubiquitin protein ligase 1a. (1068 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1971 aa)
wnk3Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
dbnlAdaptor related protein complex 2 subunit sigma 1. (455 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (775 aa)
mib1Uncharacterized protein. (1046 aa)
srcin1AIP3 domain-containing protein. (1702 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
dtnbp1Nuclear receptor coactivator 1. (355 aa)
gdf5-2Growth differentiation factor 5. (1420 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1640 aa)
PCLOPiccolo presynaptic cytomatrix protein. (3386 aa)
shisa9Protein shisa-9; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity). (390 aa)
nptnUncharacterized protein. (407 aa)
insyn1Uncharacterized protein. (247 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1318 aa)
TANC1Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1828 aa)
pkp4Proteoglycan 4. (1249 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1058 aa)
homer2Lactate dehydrogenase B. (382 aa)
INSYN2AInhibitory synaptic factor 2A. (478 aa)
ARCActivity regulated cytoskeleton associated protein. (369 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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