STRINGSTRING
sncb sncb erp29-2 erp29-2 tpr tpr WDFY3 WDFY3 sqstm1 sqstm1 xrn2 xrn2 psen1 psen1 pold1 pold1 TRIM66 TRIM66 nup98 nup98 lrrk2 lrrk2 atf4 atf4 ZBTB14 ZBTB14 ranbp2 ranbp2 hoxc9 hoxc9 trim37 trim37 CARD14 CARD14 slf1 slf1 KLHL14 KLHL14 AGL AGL hoxc9-2 hoxc9-2 htt htt pabpn1 pabpn1 rnf32 rnf32 rangap1 rangap1 PRDM16 PRDM16 URB2 URB2 hspb7 hspb7 fbxo7 fbxo7 edem1 edem1 rad18 rad18 bag5 bag5 atxn1 atxn1 nup153 nup153 herpud1 herpud1 hoxd3 hoxd3 sfmbt2 sfmbt2 arih1 arih1 nbn nbn
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sncbBeta-synuclein; Belongs to the synuclein family. (134 aa)
erp29-2Endoplasmic reticulum protein 29. (164 aa)
tprSOS Ras/Rho guanine nucleotide exchange factor 2. (2324 aa)
WDFY3WD repeat and FYVE domain containing 3. (3522 aa)
sqstm1Uncharacterized protein. (452 aa)
xrn25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (960 aa)
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
pold1DNA polymerase. (1191 aa)
TRIM66Tripartite motif containing 66. (1242 aa)
nup98Peptidase S59 domain-containing protein. (1790 aa)
lrrk2Hes family bHLH transcription factor 2. (2514 aa)
atf4Activating transcription factor 4 (Tax-responsive enhancer element B67). (343 aa)
ZBTB14Zinc finger and BTB domain containing 14. (452 aa)
ranbp2Mucolipin 2. (2842 aa)
hoxc9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (269 aa)
trim37Cysteine-serine-rich nuclear protein 1. (1031 aa)
CARD14Caspase recruitment domain family member 14. (994 aa)
slf1Teratocarcinoma-derived growth factor 1, member 3. (910 aa)
KLHL14Kelch like family member 14. (610 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1532 aa)
hoxc9-2Synapsin II. (81 aa)
httDihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). (3110 aa)
pabpn1Polyadenylate-binding protein 2; Involved in the 3'-end formation of mRNA precursors (pre- mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length. Increases the affinity of poly(A) polymerase for RNA. Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation. (296 aa)
rnf32G protein-coupled receptor 150. (382 aa)
rangap1Transcription factor 7-like 1. (582 aa)
PRDM16PR/SET domain 16. (1168 aa)
URB2URB2 ribosome biogenesis homolog. (1527 aa)
hspb7Signal sequence receptor, alpha (translocon-associated protein alpha). (161 aa)
fbxo7F-box domain-containing protein. (499 aa)
edem1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (619 aa)
rad18Zinc finger, CCHC domain containing 24. (487 aa)
bag5Bag5 protein. (450 aa)
atxn1Polymerase (RNA) II subunit H. (792 aa)
nup153Uncharacterized protein. (1566 aa)
herpud1Ubiquitin-like domain-containing protein. (366 aa)
hoxd3Cytosolic arginine sensor for mTORC1 subunit 2. (415 aa)
sfmbt2Ankyrin repeat domain 13B. (828 aa)
arih1E3 ubiquitin-protein ligase arih1; E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 ube2l3. Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL) complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets. The initial ubiquitin is then elongated. E3 ubiquitin- protein ligase activity is activated upon binding to neddylated cullin- RING ubiquitin ligase com [...] (535 aa)
nbnNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (806 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.