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| | acss2.2 | Uncharacterized protein. (697 aa) |
| | slc27a6 | Microtubule associated scaffold protein 1. (690 aa) |
| | gars1 | Transmembrane protein 37. (745 aa) |
| | asnsd1 | Glutamine amidotransferase type-2 domain-containing protein. (610 aa) |
| | acsl1 | Queuine tRNA-ribosyltransferase accessory subunit 2. (731 aa) |
| | glul | Glutamine synthetase. (371 aa) |
| | lig4 | DNA ligase. (911 aa) |
| | c17orf80 | Ephrin-B1. (314 aa) |
| | asns | Asparagine synthetase [glutamine-hydrolyzing]. (561 aa) |
| | yars2 | Tyrosine--tRNA ligase. (464 aa) |
| | acsl6 | Uncharacterized protein. (732 aa) |
| | ENSXETP00000005678 | Membrane associated ring-CH-type finger 9. (250 aa) |
| | atp5po | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (227 aa) |
| | entpd7 | Ectonucleoside triphosphate diphosphohydrolase 7; Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP (By similarity). (617 aa) |
| | tars1 | AA_TRNA_LIGASE_II domain-containing protein. (724 aa) |
| | pld1-2 | Phospholipase D1. (919 aa) |
| | PCCB | Propionyl-CoA carboxylase subunit beta. (561 aa) |
| | acsf3 | Uncharacterized protein. (610 aa) |
| | fpgs | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (589 aa) |
| | ENSXETP00000007749 | Uncharacterized protein. (315 aa) |
| | usp15 | Ubiquitin carboxyl-terminal hydrolase 15; Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling and NF-kappa-B pathways. Acts as a key regulator of TGF-beta receptor signaling pathway, but the precise mechanism is still unclear: according to a report, acts by promoting deubiquitination of monoubiquitinated R-SMADs, thereby alleviating inhibition of R-SMADs and promoting activation of TGF-beta target genes. According to another reports, regulates the TGF-beta receptor signaling pathway by mediating deubiqu [...] (982 aa) |
| | sars1 | SMAD specific E3 ubiquitin protein ligase 1. (559 aa) |
| | nkrf-2 | NFKB repressing factor. (97 aa) |
| | ttll11 | RAB24, member RAS oncogene family. (739 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (709 aa) |
| | lars2 | Bone morphogenetic protein 8 (osteogenic protein 2); Belongs to the class-I aminoacyl-tRNA synthetase family. (914 aa) |
| | rbfox2 | RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons (By similarity). (444 aa) |
| | ttll2 | Actin binding LIM protein family member 2. (478 aa) |
| | rtca | Uncharacterized protein. (369 aa) |
| | glul-2 | Glutamine synthetase. (373 aa) |
| | GMPS | Guanine monophosphate synthase. (763 aa) |
| | acsl5 | AMP-binding domain-containing protein. (329 aa) |
| | uba5 | Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates UFM1 and SUMO2. Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. (399 aa) |
| | TTLL10 | Tubulin tyrosine ligase like 10. (549 aa) |
| | LOC100490189 | Adaptor related protein complex 1 subunit beta 1. (700 aa) |
| | LOC101734368 | RNA pseudouridylate synthase domain containing 2. (107 aa) |
| | ass1 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. (429 aa) |
| | WARS2 | Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (278 aa) |
| | ENSXETP00000011893 | THO complex subunit 4. (136 aa) |
| | ENSXETP00000011995 | TGS domain-containing protein. (152 aa) |
| | ctps2 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (599 aa) |
| | qrsl1 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (557 aa) |
| | FARS2 | Phenylalanyl-tRNA synthetase 2, mitochondrial. (430 aa) |
| | ttl | Ttl protein. (377 aa) |
| | sae1 | SUMO-activating enzyme subunit 1; The heterodimer acts as an E1 ligase for sumo1, sumo2, and sumo3. It mediates ATP-dependent activation of sumo proteins followed by formation of a thioester bond between a sumo protein and a conserved active site cysteine residue on uba2/sae2 (By similarity). Belongs to the ubiquitin-activating E1 family. (347 aa) |
| | lars1 | MGC97760 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1177 aa) |
| | mthfd1 | Uncharacterized protein. (952 aa) |
| | gatc | Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (144 aa) |
| | ttll3 | Uncharacterized protein. (749 aa) |
| | acsl3 | Uncharacterized protein. (727 aa) |
| | ttll5 | Membrane bound O-acyltransferase domain containing 7. (1126 aa) |
| | tars2 | AA_TRNA_LIGASE_II domain-containing protein. (731 aa) |
| | farsb | Phenylalanine tRNA synthetase like beta subunit. (588 aa) |
| | atp5mf | Uncharacterized protein. (147 aa) |
| | atp6v1a | Glypican 5. (596 aa) |
| | hars2 | AA_TRNA_LIGASE_II domain-containing protein. (367 aa) |
| | gatb | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (519 aa) |
| | NARS2 | Asparaginyl-tRNA synthetase 2, mitochondrial. (608 aa) |
| | LOC100498257 | StAR-related lipid transfer (START) domain containing 15; Belongs to the glutamine synthetase family. (397 aa) |
| | pc.2 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1214 aa) |
| | suclg2 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa) |
| | GHDC | GH3 domain containing. (592 aa) |
| | CARS2 | Probable cysteine--tRNA ligase, mitochondrial. (608 aa) |
| | CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (1995 aa) |
| | LOC100494473 | Bromodomain adjacent to zinc finger domain 1A. (735 aa) |
| | mars1 | WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (905 aa) |
| | atp5f1d | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit. (162 aa) |
| | vars | Kinesin family member 18A; Belongs to the class-I aminoacyl-tRNA synthetase family. (1269 aa) |
| | ACSS2 | Acyl-CoA synthetase short chain family member 2. (705 aa) |
| | UBA6 | Ubiquitin like modifier activating enzyme 6. (1037 aa) |
| | ctps1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (602 aa) |
| | iars1 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1268 aa) |
| | adssl1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. Belongs to the adenylosuccinate synthetase family. (468 aa) |
| | penk-2 | Proenkephalin. (49 aa) |
| | ACSL4 | Acyl-CoA synthetase long chain family member 4. (633 aa) |
| | TTLL1 | Tubulin tyrosine ligase like 1. (412 aa) |
| | gss | Glutathione synthetase. (506 aa) |
| | carns1 | Microtubule associated protein 1B. (1011 aa) |
| | ENSXETP00000024023 | Uncharacterized protein. (372 aa) |
| | atp5f1a | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
| | mccc1 | Heterochromatin protein 1, binding protein 3. (716 aa) |
| | fnta-3 | Farnesyltransferase, CAAX box, alpha. (376 aa) |
| | rab23-2 | RAB23, member RAS oncogene family. (220 aa) |
| | mthfd1l | Calmodulin-like protein 4. (958 aa) |
| | ttll7 | Tubulin polyglutamylase TTLL7; Polyglutamylase which preferentially modifies beta-tubulin (By similarity). Mediates both ATP-dependent initiation and elongation of polyglutamylation of microtubules. Required for neurite growth; responsible for the strong increase in tubulin polyglutamylation during postnatal neuronal maturation (By similarity). Belongs to the tubulin--tyrosine ligase family. (908 aa) |
| | pfas | Glutamine amidotransferase type-1 domain-containing protein. (1351 aa) |
| | sars2 | AA_TRNA_LIGASE_II domain-containing protein. (513 aa) |
| | acsm3 | ATPase, class I, type 8B, member 4. (583 aa) |
| | nadsyn1 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (733 aa) |
| | aars1 | Lysine methyltransferase 5B; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. (999 aa) |
| | lig3 | DNA ligase. (982 aa) |
| | uba2 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for sumo1, sumo2, and sumo3. It mediates ATP-dependent activation of sumo proteins followed by formation of a thioester bond between a sumo protein and a conserved active site cysteine residue on uba2/sae2 (By similarity). (760 aa) |
| | paics.1 | AIRC domain-containing protein. (490 aa) |
| | aasdh | Receptor associated protein of the synapse. (1084 aa) |
| | yars1 | Tyrosine--tRNA ligase, cytoplasmic; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). (493 aa) |
| | rimklb | ATP-grasp domain-containing protein. (396 aa) |
| | uba3 | Immunoglobulin superfamily member 9B. (462 aa) |
| | cars1 | Cysteine--tRNA ligase, cytoplasmic. (729 aa) |
| | SMIM36 | Small integral membrane protein 36. (87 aa) |
| | naprt | Zinc finger protein 33A. (216 aa) |
| | rars1 | Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. (688 aa) |
| | RARS2 | Arginyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (578 aa) |
| | aacs | Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA. (727 aa) |
| | nae1 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (533 aa) |
| | supt20hl1 | Uncharacterized protein. (75 aa) |
| | tpgs1 | SLU7 homolog, splicing factor. (284 aa) |
| | ppcs | Thioredoxin-related transmembrane protein 1. (324 aa) |
| | rimkla | ATP-grasp domain-containing protein. (381 aa) |
| | MARS2 | Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (571 aa) |
| | acacb | Leucine zipper transcription factor like 1. (2427 aa) |
| | ttll12 | Homeobox protein OTX2. (544 aa) |
| | lrrc47 | LOC100145802 protein. (570 aa) |
| | tlr5-2 | Toll like receptor 5. (740 aa) |
| | slc38a7-2 | Insulin-induced gene 2 protein. (137 aa) |
| | gart | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1016 aa) |
| | hlcs | Engrailed homeobox 2. (853 aa) |
| | NARS1 | Asparaginyl-tRNA synthetase. (561 aa) |
| | acsbg2 | AMP-binding domain-containing protein. (759 aa) |
| | trim13 | Tripartite motif containing 13; E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins (By similarity). (408 aa) |
| | ttyh2-2 | Protein tweety homolog 2. (374 aa) |
| | tbc1d16-2 | TBC1 domain family member 16. (166 aa) |
| | suclg1 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa) |
| | hars | Malate synthase, glyoxysomal. (513 aa) |
| | acaca | Contactin 5. (2359 aa) |
| | PCCA | Propionyl-CoA carboxylase subunit alpha. (723 aa) |
| | slc27a3 | Shisa family member 3. (621 aa) |
| | ubxn2a-2 | UBX domain protein 2A; Belongs to the class-I aminoacyl-tRNA synthetase family. (161 aa) |
| | ears2 | Probable glutamate--tRNA ligase, mitochondrial; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (516 aa) |
| | dip2a | Family with sequence similarity 83 member B. (1573 aa) |
| | sucla2 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (469 aa) |
| | dalrd3 | LIM homeobox 2. (574 aa) |
| | ACSS3 | Acyl-CoA synthetase short chain family member 3. (719 aa) |
| | farsa | AA_TRNA_LIGASE_II domain-containing protein. (509 aa) |
| | acsf2 | Solute carrier family 19 member 2. (599 aa) |
| | iars2 | NIMA-related kinase 5; Belongs to the class-I aminoacyl-tRNA synthetase family. (1098 aa) |
| | ttll13p | Uncharacterized protein. (579 aa) |
| | mccc2 | Uncharacterized protein. (566 aa) |
| | mthfs | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (204 aa) |
| | QARS1 | Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (772 aa) |
| | kars1 | Lysine--tRNA ligase. (610 aa) |
| | pars2 | LOC100145097 protein. (466 aa) |
| | cps1 | Carbamoyl-phosphate synthase 1. (1462 aa) |
| | pde4b-2 | TBC1 domain family member 24. (281 aa) |
| | gclc | Glutamate-cysteine ligase, catalytic subunit. (637 aa) |
| | DARS2 | Aspartyl-tRNA synthetase 2, mitochondrial. (639 aa) |
| | rtcb | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (528 aa) |
| | lig1 | DNA ligase. (1085 aa) |
| | sdad1 | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (714 aa) |
| | atp5f1c | ATP synthase subunit gamma. (297 aa) |
| | SLC27A4 | Solute carrier family 27 member 4. (643 aa) |
| | mocs3 | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (434 aa) |
| | itch | E3 ubiquitin-protein ligase. (853 aa) |
| | wars1 | WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (517 aa) |
| | mettl2b | tRNA N(3)-methylcytidine methyltransferase METTL2; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). (695 aa) |
| | vars2 | Elastin microfibril interfacer 3; Belongs to the class-I aminoacyl-tRNA synthetase family. (1080 aa) |
| | dars1 | Cell death inducing DFFA like effector b. (531 aa) |
| | eprs1 | Solute carrier family 12, member 9. (1715 aa) |
| | magi3 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes; Belongs to the MAGUK family. (1595 aa) |
| | NEFL | Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. (554 aa) |
| | adss | Adenylosuccinate synthetase isozyme 2 A; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. (477 aa) |
| | LOC100497391 | LanC like 3. (582 aa) |
| | lrrc3 | Leucine rich repeat containing 3. (682 aa) |
| | gclm | Glutamate-cysteine ligase, modifier subunit. (274 aa) |
| | ttll4 | Squamous cell carcinoma antigen recognized by T cells 3. (1114 aa) |
| | LOC100158544 | Uncharacterized protein. (901 aa) |
| | DPH6 | Diphthamine biosynthesis 6. (697 aa) |
| | washc5 | WASH complex subunit 5; Acts at least in part as component of the WASH complex which seems to regulate washc1 nucleation-promoting factor (NPF) activity and is required for its membrane targeting during endosomal sorting. (1159 aa) |
| | atp5f1b | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (541 aa) |
| | SLC27A2 | Solute carrier family 27 member 2. (668 aa) |
| | ENSXETP00000054447 | Uncharacterized protein. (94 aa) |
| | tars3 | Threonine--tRNA ligase 2, cytoplasmic; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post- transfer stage. (814 aa) |
