STRINGSTRING
edn1 edn1 GRM5 GRM5 tpcn1 tpcn1 ENSXETP00000003747 ENSXETP00000003747 itpr2 itpr2 grin2d grin2d tpcn2 tpcn2 rcan1 rcan1 PPP1R9A PPP1R9A nfatc3 nfatc3 kdr kdr mcoln3 mcoln3 wdr92 wdr92 LOC101734792 LOC101734792 htr2b htr2b ednrb ednrb NFATC4 NFATC4 LOC100144286 LOC100144286 ppp1r9al ppp1r9al GRIN2B GRIN2B ACKR4 ACKR4 p2rx4 p2rx4 nfatc2 nfatc2 TNFSF11 TNFSF11 ncald ncald lrrk2 lrrk2 ppp3cc ppp3cc rcan2 rcan2 ppp3ca ppp3ca trpm4 trpm4 CXCR5 CXCR5 NFAT5 NFAT5 edn2 edn2 LOC100125166 LOC100125166 mcoln1 mcoln1 agtr1 agtr1 CCR7 CCR7 ccr2 ccr2 ENSXETP00000023590 ENSXETP00000023590 adgrl1 adgrl1 CCR9 CCR9 casq1 casq1 ENSXETP00000026598 ENSXETP00000026598 ebna1bp2-4 ebna1bp2-4 ppp1r9b ppp1r9b PLN PLN hpca hpca Ccl20 Ccl20 rcan3 rcan3 LOC100495031 LOC100495031 dmtn dmtn zmpste24 zmpste24 add1-2 add1-2 ptgfr ptgfr slc9a1 slc9a1 top1mt top1mt mcoln2 mcoln2 ENSXETP00000032157 ENSXETP00000032157 mknk2 mknk2 cxcr3 cxcr3 pkd2 pkd2 prkaa1 prkaa1 eif2ak3 eif2ak3 syk syk CCR8 CCR8 ppp3cb ppp3cb bhlha15 bhlha15 ednrb2 ednrb2 GRIN2C GRIN2C PLCG1 PLCG1 hpcal1 hpcal1 PLCG2 PLCG2 nmur1 nmur1 gpr143 gpr143 itpr1 itpr1 nfatc1 nfatc1 cxcr4 cxcr4 GRM1 GRM1 RYR1 RYR1 CCR6 CCR6 trpm8b trpm8b trpm8 trpm8 itpr3 itpr3 ackr3 ackr3 ryr3 ryr3 GRIN2A GRIN2A trpa1 trpa1 homer2 homer2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
edn1Nidogen 2. (222 aa)
GRM5Glutamate metabotropic receptor 5. (1172 aa)
tpcn1DDB1 and CUL4 associated factor 15. (750 aa)
ENSXETP00000003747G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
itpr2SFI1 centrin-binding protein. (2144 aa)
grin2dShort chain dehydrogenase/reductase family 42E, member 1. (1274 aa)
tpcn2Hook microtubule-tethering protein 1. (770 aa)
rcan1Uncharacterized LOC100145533. (235 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1156 aa)
nfatc3Galectin 9. (894 aa)
kdrTransglutaminase 6; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1349 aa)
mcoln3WD repeat, sterile alpha motif and U-box domain containing 1. (554 aa)
wdr92WD repeat-containing protein 92; Seems to act as a modulator of apoptosis. (633 aa)
LOC101734792SAM and SH3 domain containing 3. (502 aa)
htr2bRas homolog family member C. (478 aa)
ednrbAconitase 2; Belongs to the G-protein coupled receptor 1 family. (433 aa)
NFATC4Nuclear factor of activated T cells 4. (1091 aa)
LOC100144286LOC100144286 protein. (362 aa)
ppp1r9alUncharacterized protein. (1337 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1449 aa)
ACKR4Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
p2rx4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)
nfatc2ADP-ribosylation factor-like protein 8A. (900 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (290 aa)
ncaldNeurocalcin-delta; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions (By similarity). (193 aa)
lrrk2Hes family bHLH transcription factor 2. (2514 aa)
ppp3ccSerine/threonine-protein phosphatase. (524 aa)
rcan2Down syndrome critical region gene 1-like 1. (243 aa)
ppp3caSerine/threonine-protein phosphatase. (522 aa)
trpm4SHC (Src homology 2 domain containing) transforming protein 2. (1206 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
NFAT5Nuclear factor of activated T cells 5. (1464 aa)
edn2Mesoderm induction early response 1, family member 2. (168 aa)
LOC100125166Methyl-CpG binding domain protein 6. (211 aa)
mcoln1Mucolipin 1. (565 aa)
agtr1Agtr1.2 protein; Belongs to the G-protein coupled receptor 1 family. (355 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (358 aa)
ccr21-acylglycerol-3-phosphate O-acyltransferase 1; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ENSXETP00000023590Uncharacterized protein. (89 aa)
adgrl1DEAH-box helicase 36; Belongs to the G-protein coupled receptor 2 family. (1452 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (368 aa)
casq1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (434 aa)
ENSXETP00000026598G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (448 aa)
ebna1bp2-4EBNA1 binding protein 2. (876 aa)
ppp1r9bFrizzled related protein 2. (791 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
hpcaHippocalcin-like protein 1. (193 aa)
Ccl20C-C motif chemokine. (85 aa)
rcan3SHC (Src homology 2 domain containing) family member 4. (235 aa)
LOC100495031Uncharacterized protein. (779 aa)
dmtnHP domain-containing protein. (416 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (472 aa)
add1-2Adducin 1; Belongs to the G-protein coupled receptor 1 family. (292 aa)
ptgfrLysosomal-associated protein transmembrane 4 alpha; Belongs to the G-protein coupled receptor 1 family. (376 aa)
slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (792 aa)
top1mtPhosphoinositide phospholipase C. (1368 aa)
mcoln2Janus kinase and microtubule interacting protein 1. (581 aa)
ENSXETP00000032157Ion_trans domain-containing protein. (263 aa)
mknk2MAP kinase-interacting serine/threonine-protein kinase 2; May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine- containing mRNA cap (By similarity). (472 aa)
cxcr3Chemokine (C-X-C motif) receptor 3; Belongs to the G-protein coupled receptor 1 family. (354 aa)
pkd2Ubiquitin carboxyl-terminal hydrolase 33. (951 aa)
prkaa1Non-specific serine/threonine protein kinase. (571 aa)
eif2ak3Carnitine palmitoyltransferase 1A (liver) like. (929 aa)
sykTyrosine-protein kinase. (611 aa)
CCR8G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (354 aa)
ppp3cbSerine/threonine-protein phosphatase. (603 aa)
bhlha15Zinc finger protein 423. (175 aa)
ednrb2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (435 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1189 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1269 aa)
hpcal1Hippocalcin-like protein 1. (187 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1256 aa)
nmur1Cyclin-dependent kinase 16; Belongs to the G-protein coupled receptor 1 family. (430 aa)
gpr143G_PROTEIN_RECEP_F2_4 domain-containing protein. (414 aa)
itpr1Complement component 1, q subcomponent binding protein. (2614 aa)
nfatc1RHD domain-containing protein. (937 aa)
cxcr4C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine cxcl12/sdf-1. Transduces a signal by increasing the intracellular calcium ion level. Signaling with cxcl12/sdf-1 mediates the directional movement of mesodermal cells during gastrulation. May play a role in the migration of embryonic presumptive primordial germ cells (pPGCs). May also be involved in regulating migration of hematopoietic stem cells into the larval liver (By similarity). (358 aa)
GRM1Glutamate metabotropic receptor 1. (1158 aa)
RYR1Ryanodine receptor 1. (4991 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (354 aa)
trpm8bCoiled-coil domain containing 125. (1090 aa)
trpm8Transient receptor potential cation channel subfamily M member 8. (1141 aa)
itpr3Inositol (1,4,5) trisphosphate receptor type 3. (2673 aa)
ackr3Chemokine (C-X-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family. (361 aa)
ryr3Zinc finger MYM-type containing 2. (4848 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1318 aa)
trpa1Transient receptor potential ankyrin 1; Belongs to the transient receptor (TC 1.A.4) family. (1144 aa)
homer2Lactate dehydrogenase B. (382 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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