STRINGSTRING
farp1 farp1 picalm picalm rnf10 rnf10 STAC STAC cyth2 cyth2 CDH7 CDH7 cbwd2-2 cbwd2-2 stac3 stac3 CDH18 CDH18 cdh9 cdh9 blk blk gngt2.1 gngt2.1 frk frk gng7 gng7 CDH1 CDH1 gna11 gna11 gng5 gng5 gna13 gna13 gramd1a gramd1a LOC100488567 LOC100488567 cdh15 cdh15 snap91 snap91 kctd1 kctd1 st14 st14 KCNAB2 KCNAB2 tnk2 tnk2 anxa1.3 anxa1.3 sytl3 sytl3 cdh11 cdh11 gnaz gnaz CDH22 CDH22 plg plg gtpbp10 gtpbp10 ENSXETP00000013152 ENSXETP00000013152 gng3 gng3 snx9 snx9 FES FES mettl1 mettl1 gngt1 gngt1 apc apc fmr1 fmr1 racgap1 racgap1 acyp1 acyp1 stoml2 stoml2 LOC100492690 LOC100492690 gnb3 gnb3 tnk2l tnk2l osbpl2 osbpl2 cdh19 cdh19 cdh26 cdh26 snap25 snap25 hck hck LOC100485633 LOC100485633 srms srms ENSXETP00000019771 ENSXETP00000019771 LOC100491469 LOC100491469 myzap myzap ptk6 ptk6 fyn fyn serpine2 serpine2 GNG8 GNG8 gng10 gng10 epn3 epn3 src src numa1 numa1 apc2 apc2 CDH12 CDH12 CDH10 CDH10 cdh6 cdh6 gng13 gng13 jup jup FGR FGR syap1 syap1 gnb1 gnb1 cyth1 cyth1 plekha4 plekha4 gnas gnas nodal3.1 nodal3.1 gna15 gna15 CDH24 CDH24 LOC100486361 LOC100486361 cdh20 cdh20 serinc2-2 serinc2-2 LOC100489307 LOC100489307 dohh-2 dohh-2 sytl1 sytl1 aak1 aak1 cdh17 cdh17 prrx2-2 prrx2-2 ptk2b ptk2b styk1 styk1 rgs8 rgs8 anxa1.1 anxa1.1 kcnab1 kcnab1 tepsin tepsin cdh5 cdh5 errfi1 errfi1 esyt2 esyt2 nexmif nexmif slbp-2 slbp-2 gnb4 gnb4 cdh8 cdh8 cngb3-2 cngb3-2 zap70 zap70 gnat2 gnat2 gnai3 gnai3 HIP1 HIP1 syk syk usp30 usp30 ctnna2 ctnna2 gna14 gna14 gng2 gng2 sytl2 sytl2 gnaq gnaq cyth3 cyth3 SHANK3 SHANK3 lyn lyn fer fer nptx2 nptx2 cdh13 cdh13 ctnnb1 ctnnb1 yes1 yes1 esyt1 esyt1 poc1b poc1b WNT2B WNT2B STAC2 STAC2 eea1 eea1 cav2 cav2 cyld cyld gng12 gng12 WNT2 WNT2 cnksr2 cnksr2 gngt2 gngt2 gnao1 gnao1 racgap1.2 racgap1.2 gnai1 gnai1 cdh2 cdh2 BLK BLK gnat1 gnat1 gnai2 gnai2 USP8 USP8 PTK2 PTK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
farp1Mucin 6, oligomeric mucus/gel-forming. (1040 aa)
picalmFukutin. (722 aa)
rnf10EGF like domain multiple 7. (754 aa)
STACSH3 and cysteine rich domain. (328 aa)
cyth2Uncharacterized protein. (408 aa)
CDH7Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
cbwd2-2COBW domain containing 1, gene 2. (87 aa)
stac3SH3 and cysteine-rich domain-containing protein 3; Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane. (346 aa)
CDH18Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (787 aa)
cdh9Contactin associated protein-like 5; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
blkTyrosine-protein kinase. (497 aa)
gngt2.1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
frkTyrosine-protein kinase. (517 aa)
gng7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (934 aa)
gna11Guanine nucleotide binding protein (G protein), alpha 11 (Gq class). (359 aa)
gng5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
gna13LOC100145489 protein. (377 aa)
gramd1aNuclear transcription factor, X-box binding like 1. (650 aa)
LOC100488567ADAM metallopeptidase with thrombospondin type 1 motif 10. (1027 aa)
cdh15Lysophosphatidic acid receptor 3; Cadherins are calcium-dependent cell adhesion proteins. (814 aa)
snap91ENTH domain-containing protein. (909 aa)
kctd1Potassium channel tetramerization domain containing 1. (302 aa)
st14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. (845 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (412 aa)
tnk2ARFGEF family member 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1106 aa)
anxa1.3Annexin. (350 aa)
sytl3HERV-H LTR-associating 2. (206 aa)
cdh11Solute carrier family 4 member 11; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
gnazCCR4-NOT transcription complex subunit 9. (355 aa)
CDH22Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (795 aa)
plgPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (782 aa)
gtpbp10GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (397 aa)
ENSXETP00000013152Uncharacterized protein. (710 aa)
gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
snx9Sorting nexin. (585 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
mettl1tRNA (guanine-N(7)-)-methyltransferase A; Methyltransferase that mediates the formation of N(7)- methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs). Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. Also acts as a methyltransferase for a subset of internal N(7)-methylguanine in mRNAs. Internal N(7)- methylguanine methylation of mRNAs regulates translation. Also methylates a specific subset of miRNAs. (287 aa)
gngt1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
apcZinc finger DHHC-type containing 1. (2833 aa)
fmr1Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C). ECO:0000250|UniProtKB:P51113, ECO:0000250|UniProtKB:Q06787. (590 aa)
racgap1Uncharacterized protein. (632 aa)
acyp1Acylphosphatase-1. (98 aa)
stoml2PHB domain-containing protein. (341 aa)
LOC100492690Eukaryotic translation initiation factor 3 subunit F. (856 aa)
gnb3Zinc finger, BED-type-containing 8. (349 aa)
tnk2lChloride channel, voltage-sensitive 5; Belongs to the protein kinase superfamily. Tyr protein kinase family. (629 aa)
osbpl2Oxysterol-binding protein; Belongs to the OSBP family. (409 aa)
cdh19Fibroblast growth factor receptor substrate 2; Cadherins are calcium-dependent cell adhesion proteins. (758 aa)
cdh26Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
snap25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
hckTyrosine-protein kinase. (489 aa)
LOC100485633Fatty acid amide hydrolase, gene 2; Cadherins are calcium-dependent cell adhesion proteins. (889 aa)
srmsTyrosine-protein kinase. (478 aa)
ENSXETP00000019771Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (246 aa)
LOC100491469Tyrosine-protein kinase. (493 aa)
myzapMyocardial zonula adherens protein; Belongs to the MYZAP family. (519 aa)
ptk6Tyrosine-protein kinase. (467 aa)
fynTyrosine-protein kinase. (538 aa)
serpine2SERPIN domain-containing protein; Belongs to the serpin family. (424 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
epn3Acyl-CoA dehydrogenase short chain. (603 aa)
srcTyrosine-protein kinase. (557 aa)
numa1Kynurenine aminotransferase 3. (2351 aa)
apc2Transmembrane protein 11. (2325 aa)
CDH12Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins. (795 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (787 aa)
cdh6Solute carrier family 35 member G1; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
gng13Guanine nucleotide binding protein (G protein), gamma 13. (67 aa)
jupUncharacterized protein. (750 aa)
FGRTyrosine-protein kinase. (522 aa)
syap1Synapse associated protein 1, SAP47 homolog. (364 aa)
gnb1Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
cyth1Uncharacterized protein. (406 aa)
plekha4N-alpha-acetyltransferase 50. (1470 aa)
gnasATPase family AAA domain-containing protein 1. (292 aa)
nodal3.1Nodal homolog 3, gene 1. (75 aa)
gna15BCL2 associated athanogene 4. (256 aa)
CDH24Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins. (623 aa)
LOC100486361Uncharacterized protein. (941 aa)
cdh20E74 like ETS transcription factor 5; Cadherins are calcium-dependent cell adhesion proteins. (804 aa)
serinc2-2Nucleoporin NUP188 homolog. (683 aa)
LOC100489307Dynein, axonemal, heavy chain 2; Belongs to the peptidase C19 family. (757 aa)
dohh-2Deoxyhypusine hydroxylase. (86 aa)
sytl1Synaptotagmin-like 2. (518 aa)
aak1Protein kinase domain-containing protein. (1251 aa)
cdh17Retinol binding protein 3. (830 aa)
prrx2-2Uncharacterized protein. (931 aa)
ptk2bUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1017 aa)
styk1Protein kinase domain-containing protein. (423 aa)
rgs8CLOCK-interacting pacemaker. (216 aa)
anxa1.1Annexin. (675 aa)
kcnab1Aldo_ket_red domain-containing protein. (429 aa)
tepsinFollistatin like 4. (649 aa)
cdh5Zinc finger RNA-binding protein; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
errfi1CD53 molecule. (404 aa)
esyt2Glycerophosphodiester phosphodiesterase domain containing 5. (687 aa)
nexmifNeurite extension and migration facto. (945 aa)
slbp-2Uncharacterized protein. (84 aa)
gnb4LOC549706 protein. (327 aa)
cdh8Feline leukemia virus subgroup C cellular receptor 1; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
cngb3-2Cyclic nucleotide gated channel beta 3. (704 aa)
zap70Tyrosine-protein kinase. (609 aa)
gnat2Uncharacterized protein. (354 aa)
gnai3Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
HIP1Huntingtin interacting protein 1. (737 aa)
sykTyrosine-protein kinase. (611 aa)
usp30Ubiquitin carboxyl-terminal hydrolase 30; Deubiquitinating enzyme that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN). (519 aa)
ctnna2Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. (965 aa)
gna14Guanine nucleotide binding protein (G protein), alpha 14. (354 aa)
gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (145 aa)
sytl2Solute carrier family 41 member 1. (2819 aa)
gnaqGuanine nucleotide binding protein (G protein), q polypeptide. (359 aa)
cyth3Olfactory receptor family 52 subfamily D member 1. (411 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1850 aa)
lynTyrosine-protein kinase. (524 aa)
ferTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
nptx2Nptx2 protein. (439 aa)
cdh13C-type lectin domain family 2 member D. (720 aa)
ctnnb1Dynactin subunit 5. (788 aa)
yes1Tyrosine-protein kinase. (565 aa)
esyt1Uncharacterized protein. (947 aa)
poc1bPOC1 centriolar protein homolog B; Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Belongs to the WD repeat POC1 family. (470 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa)
STAC2SH3 and cysteine rich domain 2. (405 aa)
eea1Ovo like zinc finger 1. (1412 aa)
cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (160 aa)
cyldTLR4 interactor with leucine-rich repeats; Belongs to the peptidase C19 family. (975 aa)
gng12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
cnksr2Mitochondrial E3 ubiquitin protein ligase 1a. (1068 aa)
gngt2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
gnao1Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O. (354 aa)
racgap1.2Bruton tyrosine kinase. (591 aa)
gnai1Uncharacterized protein. (397 aa)
cdh2Jumonji domain containing 6; Cadherins are calcium-dependent cell adhesion proteins. (929 aa)
BLKTyrosine-protein kinase. (503 aa)
gnat1THAP domain containing 7. (350 aa)
gnai2Uncharacterized protein. (358 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1058 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1122 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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