STRINGSTRING
cep76 cep76 rab3gap2-2 rab3gap2-2 FLNA FLNA fkbp1b fkbp1b sri sri ank3 ank3 actn1 actn1 tnni2 tnni2 lman1 lman1 pdlim4 pdlim4 chordc1 chordc1 csrp3 csrp3 rbmx2-2 rbmx2-2 plpp4-2 plpp4-2 trim63-2 trim63-2 cplx3 cplx3 myl4 myl4 tmod4 tmod4 pno1 pno1 LOC100488020 LOC100488020 dctn4 dctn4 ankrd2 ankrd2 klhl40 klhl40 PALLD PALLD tnnt2 tnnt2 Tnni1 Tnni1 csrp1 csrp1 tnni1 tnni1 itgb1bp2 itgb1bp2 stk4 stk4 ANK2 ANK2 ENSXETP00000010352 ENSXETP00000010352 homer1 homer1 fhl5 fhl5 myot myot pdlim7 pdlim7 LOC101732337 LOC101732337 nrap nrap MYOM3 MYOM3 tnni3 tnni3 TNNT1 TNNT1 ilk ilk sqstm1 sqstm1 LOC100486532 LOC100486532 simc1 simc1 lmbr1-2 lmbr1-2 trim63 trim63 hpca-2 hpca-2 CAVIN4 CAVIN4 psen1 psen1 fhl2 fhl2 LOC100144954 LOC100144954 myom1 myom1 arhgef25 arhgef25 c7orf57 c7orf57 neb neb PARVA PARVA pdlim3 pdlim3 ldb3 ldb3 krt8.1 krt8.1 myzap myzap stub1 stub1 ABCC9 ABCC9 csrp2 csrp2 abra abra tnnt3 tnnt3 psen2 psen2 jup jup pdlim1 pdlim1 LMOD1 LMOD1 actn4 actn4 casq1 casq1 TMOD1 TMOD1 hspb1 hspb1 parvb parvb ankrd60 ankrd60 actn2 actn2 myoz2 myoz2 synpo2 synpo2 actn3 actn3 myl3 myl3 NBR1 NBR1 unc45b unc45b tnnc2 tnnc2 synpo synpo myoz3 myoz3 fbxo32 fbxo32 LRRC10 LRRC10 tmtc3-2 tmtc3-2 ENSXETP00000031913 ENSXETP00000031913 nos1ap nos1ap LRRC10B LRRC10B cryab cryab lyl1-2 lyl1-2 smtnl2 smtnl2 LOC100488346 LOC100488346 PGM5 PGM5 synpo2l synpo2l myoz1 myoz1 mtm1 mtm1 tnnc1 tnnc1 trim32 trim32 pdlim5 pdlim5 rtn2 rtn2 pdlim2 pdlim2 csrnp3-2 csrnp3-2 ANK1 ANK1 smn1 smn1 ctnnb1 ctnnb1 c10orf71 c10orf71 asb2 asb2 tcap tcap ggps1 ggps1 megf10 megf10 ankrd40 ankrd40 ccdc38 ccdc38 SYNE1 SYNE1 NEXN NEXN RYR1 RYR1 scn3b scn3b hao2-2 hao2-2 smpx smpx FLNB FLNB MYPN MYPN myl7 myl7 FBXL22 FBXL22 ryr3 ryr3 lmod2 lmod2 actc1 actc1 tmod3 tmod3 tmod2 tmod2 fhl3 fhl3 LOC100492885 LOC100492885 flnc flnc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cep76Centrosomal protein of 76 kDa; Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication (By similarity). (661 aa)
rab3gap2-2F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (219 aa)
FLNAFilamin A. (2578 aa)
fkbp1bPeptidylprolyl isomerase. (108 aa)
sriSorcin. (195 aa)
ank3Tropomyosin 4. (4214 aa)
actn1Uncharacterized protein. (890 aa)
tnni2Cytochrome b561. (188 aa)
lman1L-type lectin-like domain-containing protein. (538 aa)
pdlim4Phosphoserine aminotransferase 1. (332 aa)
chordc1Uncharacterized protein. (335 aa)
csrp3Cysteine and glycine-rich protein 2. (194 aa)
rbmx2-2RNA binding motif protein X-linked 2. (174 aa)
plpp4-2Phospholipid phosphatase 4. (563 aa)
trim63-2Tripartite motif containing 63. (351 aa)
cplx3L-type lectin-like domain-containing protein. (472 aa)
myl44-aminobutyrate aminotransferase. (190 aa)
tmod4Uncharacterized protein. (381 aa)
pno1RNA-binding protein PNO1; Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA. Belongs to the PNO1 family. (238 aa)
LOC100488020PID domain-containing protein. (287 aa)
dctn4Dynactin 4 (P62). (470 aa)
ankrd2Egl-9 family hypoxia-inducible factor 1. (310 aa)
klhl40Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. (614 aa)
PALLDPalladin, cytoskeletal associated protein. (1414 aa)
tnnt2Plexin A4. (259 aa)
Tnni1Uncharacterized protein. (152 aa)
csrp1Uncharacterized protein. (220 aa)
tnni1Thrombospondin 1. (198 aa)
itgb1bp2Lymphoid-restricted membrane protein-like. (375 aa)
stk4Serine/threonine-protein kinase 4 18kDa subunit; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein stk3/mst2 and stk4/mst1, in complex with its regulatory protein sav1, phosphorylates and activates lats1/2 in complex with its regul [...] (485 aa)
ANK2Ankyrin 2. (4497 aa)
ENSXETP00000010352Costars domain-containing protein. (148 aa)
homer1Prolactin-releasing peptide receptor-like. (394 aa)
fhl5Fhl5 protein. (282 aa)
myotH2A histone family member J. (497 aa)
pdlim7Rho guanine nucleotide exchange factor 40. (521 aa)
LOC101732337Uncharacterized protein. (281 aa)
nrapCalcium channel, voltage-dependent, gamma subunit 4. (1692 aa)
MYOM3Myomesin 3. (1232 aa)
tnni3Transmembrane protein 256. (245 aa)
TNNT1Troponin T1, slow skeletal type. (192 aa)
ilkUncharacterized protein. (286 aa)
sqstm1Uncharacterized protein. (452 aa)
LOC100486532TGc domain-containing protein. (608 aa)
simc1Uncharacterized protein. (653 aa)
lmbr1-2Limb region 1 protein homolog. (545 aa)
trim63Uncharacterized protein. (376 aa)
hpca-2Hippocalcin. (2630 aa)
CAVIN4Caveolae associated protein 4. (358 aa)
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
fhl2LOC100145283 protein. (279 aa)
LOC100144954Uncharacterized protein. (357 aa)
myom1NIPA-like domain containing 4. (1431 aa)
arhgef25Solute carrier family 6 member 2. (753 aa)
c7orf57Uncharacterized protein. (257 aa)
nebAnkyrin repeat and sterile alpha motif domain-containing 1B. (6957 aa)
PARVAParvin alpha. (254 aa)
pdlim3Forkhead box I4, gene 2. (361 aa)
ldb3SPRY domain containing 3. (668 aa)
krt8.1Keratin 8; Belongs to the intermediate filament family. (508 aa)
myzapMyocardial zonula adherens protein; Belongs to the MYZAP family. (519 aa)
stub1Novel C3HC4 type (RING finger) and B-box zinc finger protein with SPRY domain. (310 aa)
ABCC9ATP binding cassette subfamily C member 9. (1136 aa)
csrp2Uncharacterized protein. (196 aa)
abraCOP9 signalosome complex subunit 3. (446 aa)
tnnt3Uncharacterized protein. (335 aa)
psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (451 aa)
jupUncharacterized protein. (750 aa)
pdlim1Ectonucleoside triphosphate diphosphohydrolase 8. (325 aa)
LMOD1Leiomodin 1. (550 aa)
actn4Uncharacterized protein. (926 aa)
casq1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (434 aa)
TMOD1Tropomodulin 1. (359 aa)
hspb1Zinc finger MYM-type containing 4; Belongs to the small heat shock protein (HSP20) family. (211 aa)
parvbUncharacterized protein. (435 aa)
ankrd60Uncharacterized protein. (325 aa)
actn2DTW domain-containing protein 1. (920 aa)
myoz2Myozenin 2. (272 aa)
synpo2Fibrillin 1. (1036 aa)
actn3Glutathione synthetase. (910 aa)
myl3Myosin, light chain 3, alkali ventricular, skeletal, slow. (188 aa)
NBR1NBR1 autophagy cargo receptor. (958 aa)
unc45bProtein unc-45 homolog B; Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain (By similarity). Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development. (930 aa)
tnnc2Uncharacterized protein. (163 aa)
synpoTransmembrane protein 147. (949 aa)
myoz3Hypothetical LOC496725. (265 aa)
fbxo32Succinate dehydrogenase complex assembly factor 2. (353 aa)
LRRC10Leucine rich repeat containing 10. (284 aa)
tmtc3-2Transmembrane and tetratricopeptide repeat containing 3. (152 aa)
ENSXETP00000031913Ig-like domain-containing protein. (286 aa)
nos1apSKI proto-oncogene. (673 aa)
LRRC10BLeucine rich repeat containing 10B. (279 aa)
cryabMitochondrial ribosomal protein L23; Belongs to the small heat shock protein (HSP20) family. (173 aa)
lyl1-2Canopy FGF signaling regulator 1. (603 aa)
smtnl2Calponin-homology (CH) domain-containing protein. (444 aa)
LOC100488346Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1239 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (579 aa)
synpo2lGS homeobox 2. (1096 aa)
myoz1Zinc finger protein 292. (311 aa)
mtm1Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). (602 aa)
tnnc1CTD small phosphatase like. (161 aa)
trim32LOC100124994 protein. (649 aa)
pdlim5PDZ and LIM domain 5 transcript variant. (583 aa)
rtn2Reticulon-2. (314 aa)
pdlim2LIM zinc-binding domain-containing protein. (149 aa)
csrnp3-2Cysteine-serine-rich nuclear protein 3. (456 aa)
ANK1Ankyrin 1. (1814 aa)
smn1Transmembrane emp24 domain-containing protein 1. (285 aa)
ctnnb1Dynactin subunit 5. (788 aa)
c10orf71Regulating synaptic membrane exocytosis 1. (1487 aa)
asb2Pantothenate kinase 2. (652 aa)
tcapDNA topoisomerase II alpha. (186 aa)
ggps1Protocadherin 8; Belongs to the FPP/GGPP synthase family. (296 aa)
megf10Multiple epidermal growth factor-like domains protein 10; Membrane receptor involved in phagocytosis. May also regulate homotypic retinal neuron repulsion. May play role in cell adhesion and motility. May also be an essential factor in the regulation of myogenesis, controlling the balance between skeletal muscle satellite cells proliferation and differentiation (By similarity); Belongs to the MEGF family. (1124 aa)
ankrd40Homeobox-containing protein 10. (345 aa)
ccdc38Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
SYNE1Spectrin repeat containing nuclear envelope protein 1. (8694 aa)
NEXNNexilin F-actin binding protein. (742 aa)
RYR1Ryanodine receptor 1. (4991 aa)
scn3bSodium channel, voltage-gated, type III, beta. (215 aa)
hao2-2Hydroxyacid oxidase 2 (long chain). (1011 aa)
smpxSmall muscle protein, X-linked. (91 aa)
FLNBFilamin B. (2667 aa)
MYPNMyopalladin. (1320 aa)
myl7Trinucleotide repeat containing 6C. (173 aa)
FBXL22F-box and leucine rich repeat protein 22. (260 aa)
ryr3Zinc finger MYM-type containing 2. (4848 aa)
lmod2LOC100145340 protein. (549 aa)
actc1Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility; Belongs to the actin family. (377 aa)
tmod3Tropomodulin 3 (Ubiquitous). (344 aa)
tmod2LOC100127704 protein. (352 aa)
fhl3Four and a half LIM domains 3. (279 aa)
LOC100492885Sorting nexin 14. (1511 aa)
flncCoenzyme Q2 4-hydroxybenzoate polyprenyltransferase. (2728 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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