STRINGSTRING
eif4e3 eif4e3 ENSXETP00000011164 ENSXETP00000011164 pex2 pex2 ilvbl ilvbl hao2 hao2 abo.3 abo.3 mboat7 mboat7 eci2 eci2 ACADM ACADM auh auh sgpp1 sgpp1 plpp4 plpp4 ENSXETP00000013981 ENSXETP00000013981 mtmr11 mtmr11 ric1-2 ric1-2 cpt1al cpt1al DGKQ DGKQ sgpp2 sgpp2 ocrl ocrl cnot3-3 cnot3-3 b4galnt1 b4galnt1 st3gal4 st3gal4 synj2 synj2 nbl1 nbl1 hsd17b12 hsd17b12 KBTBD8 KBTBD8 mboat2 mboat2 cyp4v2.1 cyp4v2.1 abcd4 abcd4 abcd2 abcd2 mboat4 mboat4 ENSXETP00000021565 ENSXETP00000021565 hao1 hao1 LPCAT3 LPCAT3 etfdh etfdh pex5 pex5 pik3cg-2 pik3cg-2 cygb cygb bdh2 bdh2 adipor1 adipor1 mtmr12 mtmr12 bmp8-2 bmp8-2 ENSXETP00000023908 ENSXETP00000023908 LOC100491742 LOC100491742 nt5c1b nt5c1b sphk1 sphk1 polr3gl-2 polr3gl-2 ccdc180 ccdc180 sacm1l sacm1l sesn2 sesn2 ehhadh ehhadh synj1 synj1 maco1-2 maco1-2 ENSXETP00000025702 ENSXETP00000025702 echs1 echs1 mtmr6 mtmr6 plpp2 plpp2 fa2h fa2h hsd17b10 hsd17b10 MTMR3 MTMR3 slc25a17 slc25a17 slc35c1 slc35c1 fign-2 fign-2 acaa2 acaa2 dgke dgke ACOXL ACOXL pes1 pes1 tpte2 tpte2 CERK CERK kxd1 kxd1 clpx-2 clpx-2 MTMR2 MTMR2 ENSXETP00000031882 ENSXETP00000031882 mmp25-2 mmp25-2 nlk.2-2 nlk.2-2 LOC100490391 LOC100490391 DGKZ DGKZ lep lep INPPL1 INPPL1 inpp5j inpp5j Agk Agk ltn1 ltn1 abo.1 abo.1 porcn porcn eci3 eci3 mgc89178 mgc89178 crata crata K9J892_XENTR K9J892_XENTR ACAD10 ACAD10 FIG4 FIG4 sphk2 sphk2 LOC100488200 LOC100488200 prkaa1 prkaa1 plpp1 plpp1 hsd17b4 hsd17b4 plppr3 plppr3 acads acads echdc2 echdc2 mtm1 mtm1 scp2 scp2 PODN PODN cpt2 cpt2 acadl acadl LOC100135382 LOC100135382 ACOX3 ACOX3 inpp5a.1 inpp5a.1 acat1 acat1 tmem130 tmem130 mtmr1 mtmr1 inpp5k inpp5k dgki dgki mlycd mlycd inpp5a.2 inpp5a.2 gcdh gcdh MTMR8 MTMR8 PLPPR2 PLPPR2 cpt1b cpt1b pex13 pex13 acaa1 acaa1 etfa etfa LOC779592 LOC779592 ACAD11 ACAD11 CERKL CERKL crat crat dgkb dgkb PLPPR5 PLPPR5 PLPPR4 PLPPR4 plpp3 plpp3 abcd3 abcd3 mboat1 mboat1 pex7 pex7 plpp5 plpp5 LOC101730957 LOC101730957 hacl1 hacl1 hadha hadha hadhb hadhb inpp5e inpp5e acox2 acox2 DGKA DGKA mtmr10 mtmr10 LOC100216114 LOC100216114 INPP5B INPP5B decr1 decr1 pip4p2 pip4p2 plpp6 plpp6 lcat lcat ephx2 ephx2 spdl1 spdl1 acat2 acat2 pten pten hadh hadh MGC147631 MGC147631 LOC100492550 LOC100492550 phyh phyh MTMR7 MTMR7 plppr1 plppr1 slc9a9 slc9a9 crot crot mtmr9 mtmr9 pip4p1 pip4p1 ENSXETP00000004514 ENSXETP00000004514 adamts2 adamts2 slc38a2 slc38a2 c1qtnf9b c1qtnf9b echdc1 echdc1 ABCD1 ABCD1 acox1 acox1 inpp5f inpp5f etfb etfb ech1 ech1 MTMR4 MTMR4 MGC147226 MGC147226 adipoq adipoq eci1 eci1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
eif4e3Eukaryotic translation initiation factor 4E type 3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. Belongs to the eukaryotic initiation factor 4E family. (166 aa)
ENSXETP00000011164Carn_acyltransf domain-containing protein. (368 aa)
pex2Peroxisomal membrane protein 3, 35kDa (Zellweger syndrome). (306 aa)
ilvblUncharacterized protein; Belongs to the TPP enzyme family. (651 aa)
hao2FMN hydroxy acid dehydrogenase domain-containing protein. (446 aa)
abo.3P21 (RAC1) activated kinase 5. (353 aa)
mboat7ATM serine/threonine kinase; Belongs to the membrane-bound acyltransferase family. (474 aa)
eci2Enoyl-[acyl-carrier-protein] reductase, mitochondrial. (411 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (481 aa)
auhUncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (329 aa)
sgpp1Sphingosine-1-phosphate phosphatase 1. (408 aa)
plpp4KIAA1522. (271 aa)
ENSXETP00000013981IPPc domain-containing protein. (387 aa)
mtmr11Homeobox A13. (623 aa)
ric1-2RIC1 homolog, RAB6A GEF complex partner 1. (378 aa)
cpt1alUncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (799 aa)
DGKQDiacylglycerol kinase. (956 aa)
sgpp2N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4. (400 aa)
ocrlHairy and enhancer of split 5, gene 2. (909 aa)
cnot3-3CCR4-NOT transcription complex subunit 3. (378 aa)
b4galnt1Beta-1,4 N-acetylgalactosaminyltransferase. (526 aa)
st3gal4Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (331 aa)
synj2Scavenger receptor class B member 1. (1551 aa)
nbl1Neuroblastoma suppressor of tumorigenicity 1; May act as a tumor suppressor. Cytokine that has an axial patterning activity. Acts like bone morpho-genetic protein (BMP) antagonist in embryonic explants. Blocks the bmp2 activity (By similarity). (211 aa)
hsd17b12Very-long-chain 3-oxoacyl-CoA reductase; Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3- hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membra [...] (320 aa)
KBTBD8Kelch repeat and BTB domain-containing protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8) complex acts by mediating monoubiquitination of target proteins (By similarity). (633 aa)
mboat2Adenosylhomocysteinase like 1; Belongs to the membrane-bound acyltransferase family. (519 aa)
cyp4v2.1Uncharacterized protein; Belongs to the cytochrome P450 family. (523 aa)
abcd4Ankyrin repeat and sterile alpha motif domain containing 6. (639 aa)
abcd2Scribbled planar cell polarity protein. (743 aa)
mboat4Thioredoxin domain containing 16; Belongs to the membrane-bound acyltransferase family. (424 aa)
ENSXETP00000021565IPPc domain-containing protein. (361 aa)
hao1FMN hydroxy acid dehydrogenase domain-containing protein. (369 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (495 aa)
etfdhElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (616 aa)
pex5TPR_REGION domain-containing protein. (611 aa)
pik3cg-2Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma. (305 aa)
cygbCytoglobin; Belongs to the globin family. (179 aa)
bdh2Neogenin 1. (280 aa)
adipor1Adiponectin receptor 1. (379 aa)
mtmr12Nuclear receptor interacting protein 3. (748 aa)
bmp8-2Uncharacterized protein. (313 aa)
ENSXETP00000023908annotation not available (313 aa)
LOC100491742Uncharacterized protein. (295 aa)
nt5c1bUncharacterized protein. (313 aa)
sphk1TBC1 domain family member 4. (526 aa)
polr3gl-2Uncharacterized protein. (309 aa)
ccdc180Uncharacterized protein. (1421 aa)
sacm1lSAC domain-containing protein. (586 aa)
sesn2Uncharacterized protein. (415 aa)
ehhadhTransmembrane protein 255A; Belongs to the enoyl-CoA hydratase/isomerase family. (727 aa)
synj1Stathmin 3. (1548 aa)
maco1-2Macoilin 1. (378 aa)
ENSXETP00000025702IPPc domain-containing protein. (358 aa)
echs1Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (287 aa)
mtmr6Zinc finger protein 362. (727 aa)
plpp2Phosphatidic acid phosphatase type 2C. (283 aa)
fa2hFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (373 aa)
hsd17b10Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (294 aa)
MTMR3Myotubularin related protein 3. (1224 aa)
slc25a17Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (328 aa)
slc35c1Exoribonuclease 1. (364 aa)
fign-2XK related 4. (56 aa)
acaa2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
dgkeDiacylglycerol kinase. (568 aa)
ACOXLAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (649 aa)
pes1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (585 aa)
tpte2Uncharacterized protein. (511 aa)
CERKCeramide kinase. (572 aa)
kxd1KxDL motif-containing protein 1; As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. May also be involved in the biogenesis of lysosome-related organelles such as melanosomes. (195 aa)
clpx-2Caseinolytic mitochondrial matrix peptidase chaperone subunit. (525 aa)
MTMR2Myotubularin related protein 2. (596 aa)
ENSXETP00000031882Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (188 aa)
mmp25-2Matrix metallopeptidase 25. (225 aa)
nlk.2-2Serine/threonine-protein kinase NLK2. (513 aa)
LOC100490391Relaxin family locus C type II; Belongs to the carnitine/choline acetyltransferase family. (789 aa)
DGKZDiacylglycerol kinase. (1105 aa)
lepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (925 aa)
inpp5jCalcium channel, voltage-dependent, T type, alpha 1I subunit. (767 aa)
AgkUncharacterized protein. (109 aa)
ltn1E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to vcp/p97 recruitment for extraction and degradation of the incomplete translation product; Belongs to the LTN1 family. (1779 aa)
abo.1Uncharacterized protein. (381 aa)
porcnAxin interactor, dorsalization associated; Belongs to the membrane-bound acyltransferase family. (259 aa)
eci3Uncharacterized protein. (341 aa)
mgc89178Mgc89178 protein. (440 aa)
crataCarn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (625 aa)
K9J892_XENTRUncharacterized protein. (47 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1133 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (741 aa)
sphk2Ubiquitin carboxyl-terminal hydrolase 47. (592 aa)
LOC100488200Ankyrin repeat domain 27. (317 aa)
prkaa1Non-specific serine/threonine protein kinase. (571 aa)
plpp1Ppap2a protein. (284 aa)
hsd17b4Uncharacterized protein. (740 aa)
plppr3LOC100145312 protein. (704 aa)
acadsUncharacterized protein. (412 aa)
echdc2LOC100135206 protein; Belongs to the enoyl-CoA hydratase/isomerase family. (294 aa)
mtm1Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). (602 aa)
scp2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (573 aa)
PODNPodocan. (598 aa)
cpt2Carnitine O-palmitoyltransferase 2, mitochondrial. (658 aa)
acadlProtein phosphatase 3 regulatory subunit B, alpha. (461 aa)
LOC100135382Inositol-trisphosphate 3-kinase C. (296 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (706 aa)
inpp5a.1Inositol polyphosphate-5-phosphatase, 40kDa. (432 aa)
acat1Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] (470 aa)
tmem130Basic leucine zipper nuclear factor 1. (424 aa)
mtmr1Myotubularin phosphatase domain-containing protein. (690 aa)
inpp5kIPPc domain-containing protein. (547 aa)
dgkiDiacylglycerol kinase. (911 aa)
mlycdLOC100145491 protein. (509 aa)
inpp5a.2Family with sequence similarity 204 member A. (410 aa)
gcdhDolichyldiphosphatase 1. (484 aa)
MTMR8Myotubularin related protein 8. (720 aa)
PLPPR2Phospholipid phosphatase related 2. (357 aa)
cpt1bPaired like homeodomain 1; Belongs to the carnitine/choline acetyltransferase family. (809 aa)
pex13Integrin subunit beta like 1. (401 aa)
acaa1Neuroligin 3; Belongs to the thiolase-like superfamily. Thiolase family. (447 aa)
etfaElectron transferring flavoprotein, alpha polypeptide. (333 aa)
LOC779592Bardet-Biedl syndrome 2. (419 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (780 aa)
CERKLCeramide kinase like. (643 aa)
cratCarn_acyltransf domain-containing protein. (631 aa)
dgkbDiacylglycerol kinase. (784 aa)
PLPPR5Phospholipid phosphatase related 5. (314 aa)
PLPPR4Phospholipid phosphatase related 4. (770 aa)
plpp3Ppap2b protein. (307 aa)
abcd3Chromosome 16 open reading frame 58. (655 aa)
mboat1Potassium voltage-gated channel subfamily A member 4; Belongs to the membrane-bound acyltransferase family. (497 aa)
pex7Ring finger protein 157. (354 aa)
plpp5RNA-binding Raly-like protein. (267 aa)
LOC101730957Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (439 aa)
hacl1Sterol-C5-desaturase; Belongs to the TPP enzyme family. (582 aa)
hadhaUncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (771 aa)
hadhbTrifunctional enzyme subunit beta, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (470 aa)
inpp5eMajor histocompatibility complex class I antigen. (607 aa)
acox2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (739 aa)
DGKADiacylglycerol kinase. (771 aa)
mtmr10Family with sequence similarity 98 member B. (776 aa)
LOC100216114Short chain dehydrogenase/reductase family 39U, member 1. (547 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (891 aa)
decr1Fructose-bisphosphatase 1. (340 aa)
pip4p2Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (276 aa)
plpp6acidPPc domain-containing protein. (276 aa)
lcatFamily with sequence similarity 53 member C. (426 aa)
ephx2Epoxide hydrolase 2, cytoplasmic. (560 aa)
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. May act as an adapter protein linking the dynein motor complex to various cargos (By similarity); Belongs to the Spindly family. (611 aa)
acat2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
hadhVPS41, HOPS complex subunit. (315 aa)
MGC147631Uncharacterized protein. (422 aa)
LOC100492550PH domain containing endocytic trafficking adaptor 2. (119 aa)
phyhTumor protein p73. (334 aa)
MTMR7Myotubularin related protein 7. (657 aa)
plppr1Phospholipid phosphatase-related protein type 1. (342 aa)
slc9a9Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (373 aa)
crotCarn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (612 aa)
mtmr9ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1. (549 aa)
pip4p1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (327 aa)
ENSXETP00000004514IPPc domain-containing protein. (375 aa)
adamts2ADAM metallopeptidase with thrombospondin type 1 motif 2. (449 aa)
slc38a2Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1 (By similarity). (503 aa)
c1qtnf9bHECT domain containing E3 ubiquitin protein ligase 3. (244 aa)
echdc1Ethylmalonyl-CoA decarboxylase; Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level; Belongs to the enoyl-CoA hydratase/isomerase family. (299 aa)
ABCD1ATP binding cassette subfamily D member 1. (761 aa)
acox1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (674 aa)
inpp5fSpermatogenesis associated 13. (1077 aa)
etfbPyruvate dehydrogenase E1 beta subunit. (302 aa)
ech1Inverted formin-2. (310 aa)
MTMR4Myotubularin related protein 4. (1093 aa)
MGC147226Saccharopine dehydrogenase (putative). (521 aa)
adipoqCollagen, type VII, alpha 1 (Epidermolysis bullosa, dystrophic, dominant and recessive). (235 aa)
eci1Dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase); Belongs to the enoyl-CoA hydratase/isomerase family. (299 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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