STRINGSTRING
tubgcp4 tubgcp4 CEP192 CEP192 tubgcp3 tubgcp3 CCDC57 CCDC57 znf207 znf207 mzt1 mzt1 nolc1-2 nolc1-2 LOC105945133 LOC105945133 nckap5l nckap5l ssna1 ssna1 CKAP5 CKAP5 erlec1 erlec1 kif19 kif19 katnb1 katnb1 LOC779521 LOC779521 kif24 kif24 kif18a kif18a TUBGCP2 TUBGCP2 ndel1 ndel1 tubgcp5 tubgcp5 tubz1 tubz1 KIF18B KIF18B slain1 slain1 kif2c kif2c ENSXETP00000034866 ENSXETP00000034866 hdgfl3 hdgfl3 itgb4 itgb4 nedd1 nedd1 SLAIN2 SLAIN2 tppp3 tppp3 stmnd1 stmnd1 nde1 nde1 adhfe1 adhfe1 bmerb1 bmerb1 stmn2 stmn2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tubgcp4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (669 aa)
CEP192Centrosomal protein 192. (2616 aa)
tubgcp3Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (906 aa)
CCDC57Coiled-coil domain containing 57. (908 aa)
znf207Monocyte to macrophage differentiation-associated. (491 aa)
mzt1Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome. (72 aa)
nolc1-2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (377 aa)
LOC105945133Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (426 aa)
nckap5lProbable cysteine--tRNA ligase, mitochondrial. (1263 aa)
ssna1Uncharacterized protein. (116 aa)
CKAP5Cytoskeleton associated protein 5. (2003 aa)
erlec1Endoplasmic reticulum lectin 1; Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non- glycosylated proteins and glycoproteins (By similarity). (481 aa)
kif19N-acylsphingosine amidohydrolase (acid ceramidase) 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1001 aa)
katnb1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (668 aa)
LOC779521BMERB domain-containing protein. (276 aa)
kif24Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (910 aa)
kif18aKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (947 aa)
TUBGCP2Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (902 aa)
ndel1Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. (345 aa)
tubgcp5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1010 aa)
tubz1Catenin alpha 1; Belongs to the tubulin family. (422 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (872 aa)
slain1SLAIN motif-containing protein 1; Microtubule plus-end tracking protein that might be involved in the regulation of cytoplasmic microtubule dynamics, microtubule organization and microtubule elongation. Belongs to the SLAIN motif-containing family. (547 aa)
kif2cKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (715 aa)
ENSXETP00000034866Transmembrane protein 17; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (304 aa)
hdgfl3PWWP domain-containing protein. (220 aa)
itgb4Stathmin; Belongs to the stathmin family. (95 aa)
nedd1WD_REPEATS_REGION domain-containing protein. (672 aa)
SLAIN2SLAIN motif family member 2. (794 aa)
tppp3Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity; Belongs to the TPPP family. (176 aa)
stmnd1Calcitonin-related polypeptide alpha. (277 aa)
nde1Nuclear distribution protein nudE homolog 1; Required for centrosome duplication and formation and function of the mitotic spindle; Belongs to the nudE family. (340 aa)
adhfe1Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity); Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily. (544 aa)
bmerb1Metastasis suppressor 1, gene 1. (206 aa)
stmn2FAT atypical cadherin 1. (221 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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