STRINGSTRING
podxl podxl itgb1bp1 itgb1bp1 ENSXETP00000018188 ENSXETP00000018188 ptpn6 ptpn6 cyp1b1 cyp1b1 RET RET abca4-3 abca4-3 lrrc45 lrrc45 tesc tesc SERPINE1 SERPINE1 fermt3 fermt3 syk syk ift74 ift74 lyn lyn cib1 cib1 NEXMIF NEXMIF def6 def6 itgb3 itgb3 dpp4 dpp4 cyp1c1 cyp1c1 EPHA8 EPHA8 LOC101733520 LOC101733520 JAM3 JAM3 kctd1 kctd1 TGFB2 TGFB2 efna1 efna1 acer2 acer2 crk crk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
podxlGamma-aminobutyric acid (GABA) B receptor, 1. (459 aa)
itgb1bp1Ficolin 1. (209 aa)
ENSXETP00000018188SH2 domain-containing protein. (66 aa)
ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (601 aa)
cyp1b1Uncharacterized protein; Belongs to the cytochrome P450 family. (550 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1101 aa)
abca4-3ATP binding cassette subfamily A member 4. (174 aa)
lrrc45Parathyroid hormone 2 receptor. (707 aa)
tescCalcineurin B homologous protein 3; Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin (By similarity); Belongs to the calcineurin regulatory subunit family. CHP subfamily. (214 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (449 aa)
fermt3Potassium channel, voltage gated eag related subfamily H, member 8. (666 aa)
sykTyrosine-protein kinase. (611 aa)
ift74Intraflagellar transport 74 homolog. (601 aa)
lynTyrosine-protein kinase. (524 aa)
cib1Calcium and integrin binding 1 (Calmyrin). (190 aa)
NEXMIFNeurite extension and migration factor. (1420 aa)
def6DEF6 guanine nucleotide exchange factor. (596 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (800 aa)
dpp4Uncharacterized protein; Belongs to the peptidase S9B family. (837 aa)
cyp1c1Smad nuclear interacting protein 1; Belongs to the cytochrome P450 family. (524 aa)
EPHA8EPH receptor A8; Belongs to the protein kinase superfamily. Tyr protein kinase family. (503 aa)
LOC101733520C-C motif chemokine. (91 aa)
JAM3Junctional adhesion molecule 3. (298 aa)
kctd1Potassium channel tetramerization domain containing 1. (302 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
efna1Ephrin RBD domain-containing protein; Belongs to the ephrin family. (146 aa)
acer2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
crkMultivesicular body subunit 12B. (297 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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