STRINGSTRING
vps72 vps72 ruvbl1 ruvbl1 mbtd1 mbtd1 yeats2 yeats2 actl6a actl6a actg1 actg1 seh1l seh1l mllt3 mllt3 ENSXETP00000010749 ENSXETP00000010749 yeats4 yeats4 ruvbl2 ruvbl2 brd8 brd8 ing3 ing3 meaf6 meaf6 dmap1 dmap1 morf4l1 morf4l1 mllt1 mllt1 msl3 msl3 epc1 epc1 epc2 epc2 TRRAP TRRAP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
vps72Guanine nucleotide binding protein (G protein), alpha 15 (Gq class). (362 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
mbtd1MBT domain-containing protein 1; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4 (By similarity). (651 aa)
yeats2Dynein axonemal assembly factor 4. (1245 aa)
actl6aUncharacterized protein; Belongs to the actin family. (440 aa)
actg1Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. (375 aa)
seh1lNucleoporin SEH1; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. Belongs to the WD repeat SEC13 family. (383 aa)
mllt3AHD domain-containing protein. (578 aa)
ENSXETP00000010749Uncharacterized protein. (41 aa)
yeats4RecQ mediated genome instability 1. (227 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (470 aa)
brd8Spastic paraplegia 7 (pure and complicated autosomal recessive). (882 aa)
ing3Inhibitor of growth protein 3; Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription (By similarity). NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage (By similarity); Belongs to the ING family. (417 aa)
meaf6Chromatin modification-related protein MEAF6; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vi [...] (250 aa)
dmap1Uncharacterized protein. (476 aa)
morf4l1Component of oligomeric golgi complex 3. (375 aa)
mllt1Pyruvate kinase L/R. (563 aa)
msl3UTP23, small subunit processome component. (393 aa)
epc1Enhancer of polycomb homolog. (767 aa)
epc2Enhancer of polycomb homolog 2; May play a role in transcription or DNA repair. Belongs to the enhancer of polycomb family. (804 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3845 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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