STRINGSTRING
CLSTN1 CLSTN1 dlg2 dlg2 dlg3 dlg3 stau1 stau1 sytl4 sytl4 cacng2 cacng2 grip1 grip1 kif5b kif5b zdhhc12 zdhhc12 homer1 homer1 cacng3 cacng3 lgi4 lgi4 dlg1 dlg1 kif5a kif5a snap25 snap25 SCRIB SCRIB cacng7 cacng7 nsg1 nsg1 hspb1 hspb1 NPHS1 NPHS1 baiap2 baiap2 rarb rarb GRIP2 GRIP2 adam22 adam22 fes fes SHANK1 SHANK1 ENSXETP00000038077 ENSXETP00000038077 nptx2 nptx2 lrrtm1 lrrtm1 kif5c kif5c impdh2 impdh2 lrrc1 lrrc1 lgi1 lgi1 reln reln MPP4 MPP4 PCLO PCLO GRIN2A GRIN2A stau2 stau2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLSTN1Calsyntenin 1. (988 aa)
dlg2Hemojuvelin BMP co-receptor. (913 aa)
dlg3Hyaluronan-mediated motility receptor (RHAMM); Belongs to the MAGUK family. (851 aa)
stau1Uncharacterized protein. (721 aa)
sytl4Synaptotagmin like 4. (246 aa)
cacng2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
grip1Nuclear respiratory factor 1. (1130 aa)
kif5bKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (962 aa)
zdhhc12Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (276 aa)
homer1Prolactin-releasing peptide receptor-like. (394 aa)
cacng3EH domain containing 4. (317 aa)
lgi4LRRCT domain-containing protein. (578 aa)
dlg1Disks large homolog 1; Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction and cell proliferation (By similarity). (927 aa)
kif5aZinc finger protein 451; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1033 aa)
snap25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
SCRIBScribble planar cell polarity protein. (945 aa)
cacng7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
nsg1DDB1- and CUL4-associated factor 13. (185 aa)
hspb1Zinc finger MYM-type containing 4; Belongs to the small heat shock protein (HSP20) family. (211 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1078 aa)
baiap2Uncharacterized protein. (554 aa)
rarbRetinoic acid receptor beta. (52 aa)
GRIP2Glutamate receptor interacting protein 2. (1122 aa)
adam22Uncharacterized protein. (918 aa)
fesVoltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (305 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (1900 aa)
ENSXETP00000038077Zf-piccolo domain-containing protein. (529 aa)
nptx2Nptx2 protein. (439 aa)
lrrtm1Cerebellar degeneration-related protein 2-like. (521 aa)
kif5cKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (959 aa)
impdh2Inosine-5'-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (594 aa)
lrrc1Uncharacterized protein. (508 aa)
lgi1Leucine-rich, glioma inactivated 1. (547 aa)
relnG protein-coupled receptor 119. (3463 aa)
MPP4Membrane palmitoylated protein 4; Belongs to the MAGUK family. (553 aa)
PCLOPiccolo presynaptic cytomatrix protein. (3386 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1318 aa)
stau2Double-stranded RNA-binding protein Staufen homolog 2; RNA-binding protein required for the microtubule-dependent transport of RNAs within polarized cell types. (726 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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