(69 nodes) Sperm flagellum network (Xenopus tropicalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wdr66	Tripeptidyl peptidase 2. (972 aa)
	rnf38	RING-type domain-containing protein. (724 aa)
	slc26a6	STAS domain-containing protein. (737 aa)
	ttll3	Uncharacterized protein. (749 aa)
	CFAP69	Cilia and flagella associated protein 69. (883 aa)
	sqstm1	Uncharacterized protein. (452 aa)
	pacrg	IKAROS family zinc finger 3. (240 aa)
	nme5	NDK domain-containing protein; Belongs to the NDK family. (222 aa)
	LOC100490189	Adaptor related protein complex 1 subunit beta 1. (700 aa)
	ENSXETP00000010459	annotation not available (189 aa)
	ENSXETP00000007749	Uncharacterized protein. (315 aa)
	qrich2	Uncharacterized protein. (941 aa)
	ccdc172	Uncharacterized protein. (249 aa)
	tacr3	Ectodermal-neural cortex 1 (with BTB domain); Belongs to the G-protein coupled receptor 1 family. (431 aa)
	tcte1	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (460 aa)
	EFCAB2	EF-hand calcium binding domain 2. (162 aa)
	rho	Rhodopsin. (354 aa)
	CCR6	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	enkur	Solute carrier family 15 member 2. (265 aa)
	ift27	Uncharacterized protein. (210 aa)
	ccdc189	Uncharacterized protein. (219 aa)
	pmfbp1	DCN1-like protein 3. (1838 aa)
	CABCOCO1	Ciliary associated calcium binding coiled-coil 1. (197 aa)
	SPEF2	Sperm flagellar 2. (1648 aa)
	tlr5-2	Toll like receptor 5. (740 aa)
	ENSXETP00000034652	Uncharacterized protein. (189 aa)
	saxo2	Vascular cell adhesion molecule 1. (471 aa)
	LOC100488346	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1239 aa)
	ttyh2-2	Protein tweety homolog 2. (374 aa)
	tbc1d16-2	TBC1 domain family member 16. (166 aa)
	ift81	Transportin 1. (674 aa)
	pacrgl	Uncharacterized protein. (230 aa)
	nme9	Uncharacterized protein. (620 aa)
	odf2	Uncharacterized protein. (828 aa)
	tekt4	Phospholipase C delta 1. (460 aa)
	Slc26a3.2	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (733 aa)
	ttc29	Transcription factor coe2. (488 aa)
	pde4b-2	TBC1 domain family member 24. (281 aa)
	LOC101732374	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (739 aa)
	slc26a3.3	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (720 aa)
	AKAP14	A-kinase anchoring protein 14. (176 aa)
	PTCHD3	Patched domain containing 3. (902 aa)
	SPAG16	Sperm associated antigen 16. (423 aa)
	RNF44	Ring finger protein 44. (505 aa)
	tekt3	Tektin 3. (490 aa)
	abhd2	Mitochondrial ribosomal protein L37. (443 aa)
	vdac2	Uncharacterized protein. (317 aa)
	LOC100158544	Uncharacterized protein. (901 aa)
	trpc4ap-2	Uncharacterized protein. (1221 aa)
	dnali1	Uncharacterized protein. (259 aa)
	spag6	Ubiquitin recognition factor in ER associated degradation 1. (520 aa)
	cfap65	Excision repair cross-complementation group 2. (1794 aa)
	gas8	GAS domain-containing protein. (484 aa)
	rsph1	Uncharacterized protein. (189 aa)
	IQCG	IQ motif containing G. (359 aa)
	spaca9	RUN domain-containing protein 3A. (224 aa)
	spata6	Coiled-coil domain-containing protein 167. (164 aa)
	cfap221	ASH domain-containing protein. (174 aa)
	kif9	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (820 aa)
	tacr1	Chromosome 16 open reading frame 87; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	ccdc181	Potassium voltage-gated channel interacting protein 3. (471 aa)
	rab23-2	RAB23, member RAS oncogene family. (220 aa)
	fnta-3	Farnesyltransferase, CAAX box, alpha. (376 aa)
	ENSXETP00000024023	Uncharacterized protein. (372 aa)
	DNAH2	Dynein axonemal heavy chain 2. (4336 aa)
	IFT88	Intraflagellar transport 88. (826 aa)
	dnai2	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3. (611 aa)
	drc3	Uncharacterized protein. (525 aa)
	allc	Allantoicase; Utilization of purines as secondary nitrogen sources, when primary sources are limiting. (389 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFAP69	ccdc189	ENSXETP00000012896	ENSXETP00000032572	Cilia and flagella associated protein 69.	Uncharacterized protein.	0.553
CFAP69	cfap221	ENSXETP00000012896	ENSXETP00000028555	Cilia and flagella associated protein 69.	ASH domain-containing protein.	0.553
DNAH2	gas8	ENSXETP00000023121	ENSXETP00000002854	Dynein axonemal heavy chain 2.	GAS domain-containing protein.	0.413
DNAH2	nme9	ENSXETP00000023121	ENSXETP00000039957	Dynein axonemal heavy chain 2.	Uncharacterized protein.	0.409
EFCAB2	nme9	ENSXETP00000002962	ENSXETP00000039957	EF-hand calcium binding domain 2.	Uncharacterized protein.	0.415
ENSXETP00000007749	rab23-2	ENSXETP00000007749	ENSXETP00000024418	Uncharacterized protein.	RAB23, member RAS oncogene family.	0.401
ENSXETP00000007749	tbc1d16-2	ENSXETP00000007749	ENSXETP00000037745	Uncharacterized protein.	TBC1 domain family member 16.	0.477
ENSXETP00000024023	rab23-2	ENSXETP00000024023	ENSXETP00000024418	Uncharacterized protein.	RAB23, member RAS oncogene family.	0.463
ENSXETP00000024023	tbc1d16-2	ENSXETP00000024023	ENSXETP00000037745	Uncharacterized protein.	TBC1 domain family member 16.	0.538
IFT88	ift27	ENSXETP00000021354	ENSXETP00000031744	Intraflagellar transport 88.	Uncharacterized protein.	0.901
IFT88	ift81	ENSXETP00000021354	ENSXETP00000038479	Intraflagellar transport 88.	Transportin 1.	0.965
IFT88	ttll3	ENSXETP00000021354	ENSXETP00000014405	Intraflagellar transport 88.	Uncharacterized protein.	0.421
IQCG	drc3	ENSXETP00000030410	ENSXETP00000018760	IQ motif containing G.	Uncharacterized protein.	0.568
IQCG	gas8	ENSXETP00000030410	ENSXETP00000002854	IQ motif containing G.	GAS domain-containing protein.	0.452
IQCG	tcte1	ENSXETP00000030410	ENSXETP00000003038	IQ motif containing G.	Hyperpolarization activated cyclic nucleotide gated potassium channel 4.	0.597
SPEF2	dnai2	ENSXETP00000033608	ENSXETP00000020362	Sperm flagellar 2.	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3.	0.552
SPEF2	ift27	ENSXETP00000033608	ENSXETP00000031744	Sperm flagellar 2.	Uncharacterized protein.	0.431
SPEF2	spag6	ENSXETP00000033608	ENSXETP00000050432	Sperm flagellar 2.	Ubiquitin recognition factor in ER associated degradation 1.	0.648
SPEF2	ttc29	ENSXETP00000033608	ENSXETP00000043853	Sperm flagellar 2.	Transcription factor coe2.	0.423
SPEF2	wdr66	ENSXETP00000033608	ENSXETP00000017134	Sperm flagellar 2.	Tripeptidyl peptidase 2.	0.448

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