STRINGSTRING
PTAFR PTAFR cyb5b-2 cyb5b-2 pglyrp1-like.1 pglyrp1-like.1 tlr7 tlr7 tlr8 tlr8 LOC100495962 LOC100495962 tent5b-2 tent5b-2 pglyrp2 pglyrp2 scarb1 scarb1 pglyrp1 pglyrp1 tnfaip8l2 tnfaip8l2 NOD1 NOD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTAFRPlatelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
cyb5b-2Cytochrome b5 type B (outer mitochondrial membrane); Belongs to the Toll-like receptor family. (1024 aa)
pglyrp1-like.1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (182 aa)
tlr7WW domain containing E3 ubiquitin protein ligase 2; Belongs to the Toll-like receptor family. (1054 aa)
tlr8Tetratricopeptide repeat domain 21B; Belongs to the Toll-like receptor family. (1036 aa)
LOC100495962TIR domain-containing protein; Belongs to the Toll-like receptor family. (1030 aa)
tent5b-2Terminal nucleotidyltransferase 5B. (185 aa)
pglyrp2PGLYRP2. (497 aa)
scarb1Coagulation factor 12 (Hageman factor); Belongs to the CD36 family. (450 aa)
pglyrp1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (214 aa)
tnfaip8l2Tumor necrosis factor alpha-induced protein 8-like protein 2; Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity); Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily. (244 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (891 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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