STRINGSTRING
snx12 snx12 tbc1d23 tbc1d23 pheta2 pheta2 rab29 rab29 tbc1d10a tbc1d10a rab7b rab7b cln5 cln5 vps26b vps26b rhobtb3 rhobtb3 SNX8 SNX8 cltcl1 cltcl1 SNX1 SNX1 ube2o ube2o vps51 vps51 washc2a washc2a ing5-2 ing5-2 trappc10 trappc10 DNA2 DNA2 snx5 snx5 vamp3 vamp3 rab6b rab6b rab9b rab9b bet1l bet1l LOC100494483 LOC100494483 vps35 vps35 tbc1d10b tbc1d10b stx10 stx10 stx5 stx5 ankfy1 ankfy1 vps54 vps54 Rab6a Rab6a heatr5b heatr5b stx6 stx6 cltc cltc slc66a2.1 slc66a2.1 VPS52 VPS52 birc2-2 birc2-2 snx6 snx6 tbc1d5 tbc1d5 GCC2 GCC2 dctn1 dctn1 vps53 vps53 tmem87a tmem87a heatr5a heatr5a ric1 ric1 washc1 washc1 vti1b vti1b vps26a vps26a gbf1 gbf1 PREPL PREPL slc66a2.2 slc66a2.2 rab9a rab9a tbc1d24.1 tbc1d24.1 SNX2 SNX2 vps29 vps29 plekhj1 plekhj1 rab41 rab41 tmem87b tmem87b snx3 snx3 ENSXETP00000035306 ENSXETP00000035306 ENSXETP00000034327 ENSXETP00000034327 golt1b golt1b vti1a vti1a RBSN RBSN stx16 stx16 arl1 arl1 pikfyve pikfyve
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
snx12PX domain-containing protein. (237 aa)
tbc1d23Poly(A)-specific ribonuclease. (710 aa)
pheta2PH domain containing endocytic trafficking adaptor 2. (249 aa)
rab29LOC100135159 protein. (204 aa)
tbc1d10aImmunoglobulin superfamily member 9. (506 aa)
rab7bUncharacterized protein. (201 aa)
cln5Fibroblast growth factor 7. (333 aa)
vps26bVacuolar protein sorting-associated protein 26B; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity). (338 aa)
rhobtb3Uncharacterized protein. (575 aa)
SNX8Sorting nexin 8. (432 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
SNX1Sorting nexin 1. (581 aa)
ube2oPhytanoyl-CoA hydroxylase-interacting protein-like. (1406 aa)
vps51Vacuolar protein sorting-associated protein 51 homolog; Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling. (782 aa)
washc2aCAP-ZIP_m domain-containing protein. (1037 aa)
ing5-2Inhibitor of growth family member 5. (115 aa)
trappc10Cyclic AMP-responsive element-binding protein 3-like protein 4. (1256 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2; Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape fen1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit dna2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by [...] (1100 aa)
snx5Sorting nexin; Involved in several stages of intracellular trafficking. (406 aa)
vamp3V-SNARE coiled-coil homology domain-containing protein. (118 aa)
rab6bUncharacterized protein. (216 aa)
rab9bRAB9B, member RAS oncogene family. (201 aa)
bet1lPOU domain, class 3, transcription factor 4. (111 aa)
LOC100494483Endoribonuclease LACTB2. (256 aa)
vps35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
tbc1d10bNeurexin 2. (782 aa)
stx10t-SNARE coiled-coil homology domain-containing protein. (252 aa)
stx5WD repeat domain 53; Belongs to the syntaxin family. (342 aa)
ankfy1Cartilage intermediate layer protein. (1187 aa)
vps54Calcium channel, voltage-dependent, T type, alpha 1G subunit. (981 aa)
Rab6aUncharacterized protein. (80 aa)
heatr5bHEAT repeat-containing protein 5B; Belongs to the HEATR5 family. (2052 aa)
stx6Regulator of G-protein signaling 10; Belongs to the syntaxin family. (264 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1692 aa)
slc66a2.1NGG1 interacting factor 3 like 1. (271 aa)
VPS52VPS52 subunit of GARP complex. (728 aa)
birc2-2PX domain-containing protein. (228 aa)
snx6Sorting nexin; Involved in several stages of intracellular trafficking. (407 aa)
tbc1d5Protein S. (773 aa)
GCC2GRIP and coiled-coil domain containing 2. (1734 aa)
dctn1CAP-Gly domain-containing protein. (1290 aa)
vps53Retinoid X receptor gamma. (830 aa)
tmem87aJNK1/MAPK8 associated membrane protein. (557 aa)
heatr5aHEAT repeat-containing protein 5A; Belongs to the HEATR5 family. (2030 aa)
ric1NOP2/Sun RNA methyltransferase family member 3. (1421 aa)
washc1WASH complex subunit 1; Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Its assembly in the WASH core complex seems to inhibit its NPF activity and is required for its membrane targeting; Belongs to the WASH1 family. (472 aa)
vti1bt-SNARE coiled-coil homology domain-containing protein. (221 aa)
vps26aVacuolar protein sorting-associated protein 26A; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity). (329 aa)
gbf1Olfactory receptor class II (xb178 gene). (1854 aa)
PREPLProlyl endopeptidase like. (703 aa)
slc66a2.2Segment polarity protein dishevelled homolog DVL-3. (238 aa)
rab9aVasodilator stimulated phosphoprotein. (201 aa)
tbc1d24.1TBC1 domain family member 24; May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections development, probably through a negative modulation of ARF6 function. (568 aa)
SNX2Sorting nexin 2. (523 aa)
vps29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity). Acts also as component of the retriever complex. The retriever complex is an heterotrimeric complex related to retromer cargo-selective com [...] (182 aa)
plekhj1Pleckstrin homology domain-containing family J member 1. (188 aa)
rab41LOC100124772 protein. (210 aa)
tmem87bTransmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN); Belongs to the LU7TM family. TMEM87 subfamily. (540 aa)
snx3Sorting nexin 12. (162 aa)
ENSXETP00000035306PH domain-containing protein. (231 aa)
ENSXETP00000034327PH domain-containing protein. (171 aa)
golt1bTelomerase reverse transcriptase. (168 aa)
vti1at-SNARE coiled-coil homology domain-containing protein. (215 aa)
RBSNRabenosyn, RAB effector. (817 aa)
stx16t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (279 aa)
arl1Suppression of tumorigenicity 7 like; Belongs to the small GTPase superfamily. Arf family. (181 aa)
pikfyveUncharacterized protein. (2104 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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