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mtap mtap ada.2 ada.2 ada ada hprt1 hprt1 nt5dc4 nt5dc4 nt5c1a nt5c1a acpp acpp nudt1 nudt1 ENSXETP00000004830 ENSXETP00000004830 nt5c2 nt5c2 adal adal NT5C1A NT5C1A LOC100145149 LOC100145149 zp3.2-2 zp3.2-2 Gnmt Gnmt gda gda aprt aprt pnp pnp NT5E NT5E prxl2a-2 prxl2a-2 ENSXETP00000025727 ENSXETP00000025727 prtfdc1 prtfdc1 ICMT ICMT DGUOK DGUOK adk adk ADA2 ADA2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
mtapS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (282 aa)
ada.2A_deaminase domain-containing protein. (415 aa)
adaAdenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (359 aa)
hprt1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (224 aa)
nt5dc4TELO2 interacting protein 1. (535 aa)
nt5c1aUncharacterized protein. (430 aa)
acppTransmembrane protein 205; Belongs to the histidine acid phosphatase family. (419 aa)
nudt1Leucine rich repeat and fibronectin type III domain containing 3; Belongs to the Nudix hydrolase family. (156 aa)
ENSXETP00000004830Uncharacterized protein. (118 aa)
nt5c2Cytosolic purine 5'-nucleotidase; May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides (By similarity). (638 aa)
adalA_deaminase domain-containing protein. (360 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (364 aa)
LOC100145149Fatty acid binding protein 3. (245 aa)
zp3.2-2Serine/arginine-rich splicing factor 4. (153 aa)
GnmtUncharacterized protein. (69 aa)
gdaGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (478 aa)
aprtAdenine phosphoribosyltransferase. (180 aa)
pnpPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (297 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (582 aa)
prxl2a-2Peroxiredoxin-like 2A. (266 aa)
ENSXETP00000025727Macro domain-containing protein. (112 aa)
prtfdc1Phosphoribosyltransferase domain-containing protein 1; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (224 aa)
ICMTProtein-S-isoprenylcysteine O-methyltransferase. (290 aa)
DGUOKDeoxyguanosine kinase. (265 aa)
adkTransmembrane phosphoinositide 3-phosphatase and tensin homolog 2. (370 aa)
ADA2Adenosine deaminase 2. (424 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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